Role of Amphotericin B in the Treatment of Mucormycosis
CONCLUSION: The article demonstrates the traits of the drug associated with its chemical, pharmacokinetics, stability, and other features, and illustrates their most useful characteristics for clinical application.PMID:38178658 | DOI:10.2174/0113816128272443231221101415 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 5, 2024 Category: Drugs & Pharmacology Authors: Alisha Sachdeva Monika Targhotra Meenakshi Kanwar Chauhan Monica Chopra Source Type: research
Poly(lactic-co-glycolic) Acid (PLGA) Nanoparticles and Transdermal Drug Delivery: An Overview
CONCLUSION: PLGA nanoparticles can be considered efficient nanocarriers for the transdermal delivery of drugs. Nevertheless, the clinical investigation of PLGA nanoparticles for the transdermal administration of therapeutic agents remains a formidable obstacle.PMID:38173050 | DOI:10.2174/0113816128275385231027054743 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Lalit Kumar Gauree Kukreti Ritesh Rana Himanshu Chaurasia Anchal Sharma Neelam Sharma None Komal Source Type: research
Recent Progress in the Hesperetin Delivery Regimes: Significance of Pleiotropic Actions and Synergistic Anticancer Efficacy
Conclusion: This article sheds light on HST structure-function correlation and pleiotropic anticancer mechanisms, in unaided and NC-administered delivery in singular and with CDs synergy. The discussion could streamline the HST usefulness and long-term anticancer efficacy.PMID:38173051 | DOI:10.2174/0113816128253609231030070414 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Parth Malik Manju Bernela Mahima Seth Priya Kaushal Tapan Kumar Mukherjee Source Type: research
Multiphasic Gels: Achieving New Drug Delivery
Curr Pharm Des. 2023;29(40):3171. doi: 10.2174/138161282940231220112709.NO ABSTRACTPMID:38173055 | DOI:10.2174/138161282940231220112709 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Manisha Pandey Shubhini A Saraf Shailendra K Saraf Source Type: research
Poly(lactic-co-glycolic) Acid (PLGA) Nanoparticles and Transdermal Drug Delivery: An Overview
CONCLUSION: PLGA nanoparticles can be considered efficient nanocarriers for the transdermal delivery of drugs. Nevertheless, the clinical investigation of PLGA nanoparticles for the transdermal administration of therapeutic agents remains a formidable obstacle.PMID:38173050 | DOI:10.2174/0113816128275385231027054743 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Lalit Kumar Gauree Kukreti Ritesh Rana Himanshu Chaurasia Anchal Sharma Neelam Sharma None Komal Source Type: research
Recent Progress in the Hesperetin Delivery Regimes: Significance of Pleiotropic Actions and Synergistic Anticancer Efficacy
Conclusion: This article sheds light on HST structure-function correlation and pleiotropic anticancer mechanisms, in unaided and NC-administered delivery in singular and with CDs synergy. The discussion could streamline the HST usefulness and long-term anticancer efficacy.PMID:38173051 | DOI:10.2174/0113816128253609231030070414 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Parth Malik Manju Bernela Mahima Seth Priya Kaushal Tapan Kumar Mukherjee Source Type: research
Multiphasic Gels: Achieving New Drug Delivery
Curr Pharm Des. 2023;29(40):3171. doi: 10.2174/138161282940231220112709.NO ABSTRACTPMID:38173055 | DOI:10.2174/138161282940231220112709 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 4, 2024 Category: Drugs & Pharmacology Authors: Manisha Pandey Shubhini A Saraf Shailendra K Saraf Source Type: research
GDF-10 Induces an Inhibitory Effect on Epithelial-Mesenchymal Transition of Laryngeal Cancer via LPR4
CONCLUSION: Our findings support that GDF-10 can inhibit the proliferation, migration, and invasion, and promote apoptosis of laryngeal carcinoma AMC-HN-8 cells. GDF-10 inhibits the EMT of laryngeal carcinoma through LRP4 and thus inhibits the progression of laryngeal carcinoma.PMID:38163971 | DOI:10.2174/0113816128261029231206035206 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: Xuan Kan Li Ai Ruidi Guan Jianwei Hao Yanan Sun Wei Xiu Source Type: research
Contemporary Management of Risk Factors in Coronary Artery Disease (Part 2)
Curr Pharm Des. 2023;29(35):2763. doi: 10.2174/138161282935231207112504.NO ABSTRACTPMID:38164729 | DOI:10.2174/138161282935231207112504 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: Dimitris Tousoulis Panagiotis Theofilis Source Type: research
Commentary on "Hyperbaric Oxygen Therapy Improves Neurocognitive Functions and Symptoms of Post-COVID Condition: Randomized Controlled Trial"
Curr Pharm Des. 2023;29(34):2679-2683. doi: 10.2174/0113816128268472231106093239.NO ABSTRACTPMID:38164733 | DOI:10.2174/0113816128268472231106093239 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: J úlia Leão Batista Simões Ge órgia de Carvalho Braga Margarete Dulce Bagatini Source Type: research
GDF-10 Induces an Inhibitory Effect on Epithelial-Mesenchymal Transition of Laryngeal Cancer via LPR4
CONCLUSION: Our findings support that GDF-10 can inhibit the proliferation, migration, and invasion, and promote apoptosis of laryngeal carcinoma AMC-HN-8 cells. GDF-10 inhibits the EMT of laryngeal carcinoma through LRP4 and thus inhibits the progression of laryngeal carcinoma.PMID:38163971 | DOI:10.2174/0113816128261029231206035206 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: Xuan Kan Li Ai Ruidi Guan Jianwei Hao Yanan Sun Wei Xiu Source Type: research
Contemporary Management of Risk Factors in Coronary Artery Disease (Part 2)
Curr Pharm Des. 2023;29(35):2763. doi: 10.2174/138161282935231207112504.NO ABSTRACTPMID:38164729 | DOI:10.2174/138161282935231207112504 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: Dimitris Tousoulis Panagiotis Theofilis Source Type: research
Commentary on "Hyperbaric Oxygen Therapy Improves Neurocognitive Functions and Symptoms of Post-COVID Condition: Randomized Controlled Trial"
Curr Pharm Des. 2023;29(34):2679-2683. doi: 10.2174/0113816128268472231106093239.NO ABSTRACTPMID:38164733 | DOI:10.2174/0113816128268472231106093239 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: J úlia Leão Batista Simões Ge órgia de Carvalho Braga Margarete Dulce Bagatini Source Type: research
A Mechanistic Review on Therapeutic Potential of Medicinal Plants and their Pharmacologically Active Molecules for Targeting Metabolic Syndrome
Curr Pharm Des. 2023 Dec 28. doi: 10.2174/0113816128274446231220113957. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) therapy with phytochemicals is an emerging field of study with therapeutic potential. Obesity, insulin resistance, high blood pressure, and abnormal lipid profiles are all components of metabolic syndrome, which is a major public health concern across the world. New research highlights the promise of phytochemicals found in foods, including fruits, vegetables, herbs, and spices, as a sustainable and innovative method of treating this illness. Anti-inflammatory, antioxidant, and insulin-sensitizing...
Source: Current Pharmaceutical Design - December 29, 2023 Category: Drugs & Pharmacology Authors: Vinod Kumar Gauttam Kavita Munjal Hitesh Chopra Aftab Ahmad Mahesh Kumar Rana Mohammad Amjad Kamal Source Type: research
Nanocomposite Hydrogels-A Promising Approach towards Enhanced Bioavailability and Controlled Drug Delivery
Curr Pharm Des. 2023 Dec 28. doi: 10.2174/0113816128283466231219071151. Online ahead of print.ABSTRACTNanotechnology has emerged as the eminent focus of today's research to overcome challenges related to conventional drug delivery systems. A wide spectrum of novel delivery systems has been investigated to improve the therapeutic outcomes of drugs. The polymer-based nanocomposite hydrogels (NCHs) that have evolved as efficient carriers for controlled drug delivery are of particular interest in this regard. Nanocomposites amalgamate the properties of both nanoparticles (NPs) as well as hydrogels, exhibiting superior function...
Source: Current Pharmaceutical Design - December 29, 2023 Category: Drugs & Pharmacology Authors: Nariman Shahid Alia Erum Sana Hanif Nadia Shamshad Malik Ume Ruqia Tulain Muhammad Ali Syed Source Type: research
