Serious health-related suffering and palliative care in South Asian countries
Purpose of review South Asia, with a population of 1.79 billion, has close to 9.9 million individuals experiencing serious health-related suffering (SHS). South Asia accounts for 10.23% of the world's cancer incidence. The prevalence of cancer mortality in the region is 68.44%, significantly higher than the world average of 59.74%. This poor outcome highlights the need to focus on SHS in the region. This review was undertaken to assess the current status of palliative care inequities in the region and to guide future action. Recent findings Using morphine-equivalent doses of opioid analgesics (excluding methadon...
Source: Current Opinion in Supportive and Palliative Care - August 6, 2021 Category: Palliative Care Tags: SOCIO-CULTURAL-ECONOMIC DETERMINANTS OF ACCESS TO QUALITY CANCER CARE: Edited by Elie Isenberg-Grzeda and Janet Ellis Source Type: research

Cancer care disparities among Australian and Aotearoa New Zealand Indigenous peoples
Purpose of review Persistent and significant inequalities for Indigenous people with cancer around the globe exist, arising from colonial settlement of Indigenous land with profound social, economic and cultural impacts. We summarize recent publications concerning cancer disparities affecting Australian Aboriginal and Torres Strait Islander Peoples and Aotearoa New Zealand Māori Peoples. Recent findings Cancer-free survival and overall survival statistics testify to the urgent need to ‘close the gap’. For Indigenous peoples in Australia and New Zealand, disparity persists along the cancer care pathway, from...
Source: Current Opinion in Supportive and Palliative Care - August 6, 2021 Category: Palliative Care Tags: SOCIO-CULTURAL-ECONOMIC DETERMINANTS OF ACCESS TO QUALITY CANCER CARE: Edited by Elie Isenberg-Grzeda and Janet Ellis Source Type: research

Unequal distribution of financial toxicity among people with cancer and its impact on access to care: a rapid review
Purpose of review Research demonstrates that patients and their families often carry a good portion of the economic burden during and following cancer treatment, frequently resulting in implications for access to care. This rapid review summarizes how this knowledge has evolved in recent years. Recent findings The number of articles on patient financial burden is increasing, suggesting awareness about the growing impact of economic burden on patients. This is particularly evident when discussing out-of-pocket costs, and lost work for patients/caregivers. However, there is an increasing focus on ‘foregone care...
Source: Current Opinion in Supportive and Palliative Care - August 6, 2021 Category: Palliative Care Tags: SOCIO-CULTURAL-ECONOMIC DETERMINANTS OF ACCESS TO QUALITY CANCER CARE: Edited by Elie Isenberg-Grzeda and Janet Ellis Source Type: research

Editorial: Socio-cultural-economic determinants of access to quality cancer care
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 6, 2021 Category: Palliative Care Tags: SOCIO-CULTURAL-ECONOMIC DETERMINANTS OF ACCESS TO QUALITY CANCER CARE: Edited by Elie Isenberg-Grzeda and Janet Ellis Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 6, 2021 Category: Palliative Care Tags: EDITORIAL INTRODUCTIONS Source Type: research

The COVID-19 pandemic: challenges in providing supportive care to those with cardiovascular disease in a time of plague
This article critically reviews how best to integrate supportive care into the management of those affected. Recent findings Numerous studies have described the pathophysiology of COVID-19, including that specifically arising in those with cardiovascular disease. Potential treatment strategies have emerged but there is limited guidance on the provision of palliative care. A framework for implementation of this service needs to be developed, perhaps involving the training of non-specialists to deliver primary palliative care in the community, bolstered by the use of telemedicine. The appropriate use of limited clinic...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Intersectionality and heart failure: what clinicians and researchers should know and do
Purpose of review To review the application of intersectionality to heart failure. Intersectionality refers to the complex ways in which disenfranchisement and privilege intersect to reproduce and influence health and social outcomes. Recent findings Intersectionality challenges approaches that focus on a single or small number of socio-demographic characteristics, such as sex or age. Instead, approaches should take account of the nature and effects of a full range of socio-demographic factors linked to privilege, including: race and ethnicity, social class, income, age, gender identity, disability, geography, a...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Cardio-oncology: rationale, aims and future directions
This article explains to the reader what cardio-oncology services provide and the nature of cardiovascular problems caused by the growing array of modern cancer therapies. Recent findings The list of potentially cardiotoxic cancer therapeutic agents is ever growing and dedicated cardio-oncology experts are required to tackle cardiovascular complications with minimal delay to necessary cancer therapy. Cardio-oncology services originated in academic centres but are now being set up around the world in all hospitals and clinics that provide care to cancer patients. Cardio-oncology plays an increasingly active role at e...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Editorial: Cardiovascular service innovation, intersectionality, and the challenges of COVID-19
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Capsaicin 8% patch Qutenza and other current treatments for neuropathic pain in chemotherapy-induced peripheral neuropathy (CIPN)
Purpose of review Current oral treatments for neuropathic pain associated with chemotherapy-induced peripheral neuropathy (CIPN) have limited clinical efficacy, and undesirable side-effects. Topically delivered treatments have the advantage of avoiding CNS side-effects, while relieving pain. We have reviewed treatments of neuropathic pain associated with CIPN, focusing on the Capsaicin 8% patch, which can provide pain relief for up to 3 months or longer after a single 30–60-min application. Recent findings Capsaicin 8% patch is a licensed treatment in the EU/UK for neuropathic pain and shown to be safe and e...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Bedside testing for precision pain medicine
Purpose of review In recent years, the identification of therapy responders has become an increasing focus of pain research. On the basis of laboratory quantitative sensory testing, subgroups of patients were identified, which have been shown to predict treatment response. However, the high cost and time expenditure limits the use of these lab-QST protocols in clinical practice and large clinical trials. Recent findings Recently, different bedside testing protocols were developed as easy-to-use alternative for lab-QST. In addition, patients can be subgrouped based on their symptoms by use of patient-reported out...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Pain in Parkinson's disease: Mechanism-based treatment strategies
Purpose of review Chronic pain, highly prevalent throughout the course of Parkinson's disease (PD), has been ranked as one of the top ten most bothersome symptoms people with Parkinson's (PwP) are experiencing. Yet, robust evidence-based treatment strategies are lacking. This unmet need is partly attributable to the multifaceted nature of PD-related pain, which results in part from a complex and poorly understood interplay involving a range of neurotransmitter pathways. Degeneration of nigrostriatal dopaminergic pathways and alterations of central nervous system extra-striatal dopaminergic, noradrenergic, serotoninergi...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Update on pain in arthritis
Purpose of review Osteoarthritis is a degenerative joint disease that features pain as a hallmark symptom. This review summarises progress and obstacles in our understanding of pain mechanisms in arthritis. Recent findings Pain phenotypes in osteoarthritis are poorly characterized in clinical studies and animal studies are largely carti-centric. Different animal models incur variable disease progression patterns and activation of distinct pain pathways, but studies reporting both structural and pain outcomes permit better translational insights. In patients, classification of osteoarthritis disease severity is o...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASES: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Evolving role of minimally invasive techniques in the management of symptomatic bone metastases
This article aims to review minimally invasive, image-guided locoregional treatments for symptomatic bone metastases as an adjunct to conventional treatment modalities. Recent findings Conservative therapy and radiation therapy (RT) can be effective at addressing pain, however, they require time to achieve optimal efficacy and do not address the instability and progressive collapse of pathological fractures. Vertebral and pelvic augmentation with cement enhances structural stability and can prevent progressive collapse and deformity. Ablative therapies, including radiofrequency ablation (RFA), cryoablation, and phot...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: CANCER: Edited by Anthony H. Dickenson and Paul Farquhar-Smith Source Type: research

Clinical practice guidelines for cancer pain: problems and solutions
Purpose of review Clinical practice guidelines (CPGs) should allow practitioners to follow the best evidence-based management for patients. The increasing specialisation of medicine and pain medicine has increased the number of CPGs, but practitioners are still facing contradictory advice that can be difficult to implement and follow. Recent findings A recent comprehensive metareview of 25 reviews have highlighted that the same issues of quality, barriers to implementation and difficulties in applicability are as prevalent as they were years ago when assessment tools (e.g. AGREE II) and recommendations for CPG d...
Source: Current Opinion in Supportive and Palliative Care - April 30, 2021 Category: Palliative Care Tags: PAIN: CANCER: Edited by Anthony H. Dickenson and Paul Farquhar-Smith Source Type: research