Does nutrition support have a role in managing cancer cachexia?
Purpose of review: Cachexia is a negative prognostic factor in cancer patients. The pathogenesis is related to a variable combination of reduced food intake and metabolic changes. However, whether nutritional support may contribute to effectively prevent and treat cachexia remains a debated issue. Recent findings: Consistent evidence demonstrates that anabolic windows of opportunity occur during the clinical trajectory of cancer patients. Also, the use of specific nutrients, namely omega-3 fatty acids, may enhance the efficacy of nutritional support when tumor-driven inflammatory response is high. Of greater interest, it ...
Source: Current Opinion in Supportive and Palliative Care - October 28, 2016 Category: Palliative Care Tags: CACHEXIA, NUTRITION AND HYDRATION: Edited by Aminah Jatoi and Florian Strasser Source Type: research

Animal models for cancer cachexia
Purpose of review: Cancer cachexia is a frequent syndrome that affects patient quality of life, anticancer treatment effectiveness, and overall survival. The lack of anticancer cachexia therapies likely relies on the complexity of the syndrome that renders difficult to design appropriate clinical trials and, conversely, on the insufficient knowledge of the underlying pathogenetic mechanisms. The aim of this review is to collect the most relevant latest information regarding cancer cachexia with a special focus on the experimental systems adopted for modeling the disease in translational studies. Recent findings: The scena...
Source: Current Opinion in Supportive and Palliative Care - October 28, 2016 Category: Palliative Care Tags: CACHEXIA, NUTRITION AND HYDRATION: Edited by Aminah Jatoi and Florian Strasser Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - October 28, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research

Prevention and management of osteonecrosis of the jaw secondary to bone-targeted therapy in patients with kidney cancer
Purpose of review: The aim of this revision is prevention and management of osteonecrosis of the jaw (ONJ) secondary to bone-targeted therapy in patients with kidney cancer. Recent findings: Patients with kidney cancer treated with zoledronate suffered from ONJ earlier compared with patients with breast cancer or multiple myeloma; among men, ONJ occurred at 24 months of zoledronic acid treatment in more than 80% of the patients and much earlier, in respect to patients with prostate cancer or multiple myeloma. Protective factors against an ONJ can be sequential prescription of different bisphosphonates and female sex. Less...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RENAL AND UROLOGICAL PROBLEMS: Edited by Fred Saad Source Type: research

Rationale for local treatment in the management of metastatic prostate cancer
Purpose of review: To evaluate the rationale supporting the role of local treatment in the management of patients with metastatic prostate cancer (PCa). Recent findings: Not all patients with metastatic PCa share the same prognosis, in which selected individuals with oligometastatic PCa might benefit from local therapies. These men would harbor a biologically different disease as compared with their counterparts with widespread metastases. Local treatment would eliminate the source of tumor-promoting factors, destroy the origin of metastatic cells, and stop the self-seeding process. Moreover, decreasing tumor burden would...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RENAL AND UROLOGICAL PROBLEMS: Edited by Fred Saad Source Type: research

The evolving role of chemotherapy in prostate cancer
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RENAL AND UROLOGICAL PROBLEMS: Edited by Fred Saad Source Type: research

Inspiring change: humanities and social science insights into the experience and management of breathlessness
This article discusses a number of current issues in understanding the experience of breathlessness. Recent findings: Effective communication concerning the experience of breathlessness is crucial for diagnosis, to identify appropriate treatment, and to provide patients with the capacity to self-manage their condition. However, there is an evident disconnect between the way breathlessness is understood between clinical and lay perspectives, in terms of awareness of breathlessness, the way symptoms are expressed, and acknowledgement of how it affects the daily lives of patients. Summary: The review highlights the need for...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

Thromboembolic disease and breathlessness
This study reviews the challenges of VTE management within supportive and palliative care, the new oral anticoagulants and the management of VTE in cases in which the evidence is lacking. (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

Breathlessness and inflammation: potential relationships and implications
Purpose of review: Breathlessness and chronic inflammation both span a wide range of disease contexts and hold prognostic significance. The possibility of a causal relationship between the two has been hypothesized. The aims of this article are to review the intersections between breathlessness and inflammation in the literature, describe potential mechanisms connecting the two phenomena, and discuss the potential clinical implications of a causal relationship. Recent findings: There is a very limited literature exploring the relationship between systemic inflammation and breathlessness in chronic obstructive pulmonary di...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

Physiological and functional failure in chronic obstructive pulmonary disease, congestive heart failure and cancer: a debilitating intersection of sarcopenia, cachexia and breathlessness
Purpose of review: Loss of skeletal muscle mass and cachexia are important manifestations of chronic obstructive pulmonary disease and have been associated with breathlessness, functional limitation and poor prognosis. A number of other life-limiting illnesses, including cancer and chronic heart failure as well as acute conditions seen in ICU such as sepsis, are characteristically associated with cachexia and sarcopenia. These conditions may have respiratory muscle atrophy of sufficient magnitude to contribute to the development of breathlessness and associated functional limitation. The purpose of this review is to summar...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

Service delivery of complex interventions for refractory breathlessness
Purpose of review: The review considers the evidence for different service models existing for helping people manage the chronic, irreversible breathlessness that accompanies advanced disease. Recent findings: Many of the service models that are delivering care have not yet published their results in the scientific literature because these ideas, and the methods to evaluate them, are relatively new. There are three randomized controlled trials published which demonstrate the effectiveness of this approach and one which suggests that more episodes of some intervention components are not necessarily better. Summary: Breath...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

What can we learn about breathlessness from population-based and administrative health data?
Purpose of review: To review the findings and methodological strengths and limitations of studies of breathlessness using population-based or routinely collected data, including the novel methodology of the registry-based randomized controlled trial (R-RCT). Recent findings: Breathlessness severe enough to restrict activity is common and increases in the last months of life both among elderly in the community and among patients in specialized palliative care. During the last week of life, risk factors for more severe breathlessness have been identified. Patients with advanced chronic obstructive or interstitial lung disea...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

Chronic breathlessness: silent and deadly
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: RESPIRATORY PROBLEMS: Edited by David C. Currow and Miriam J. Johnson Source Type: research

A positive risk approach when clients choose to live at risk: a palliative case discussion
Purpose of review: The article discusses recent approaches in the literature about clients who chose to live at risk in their homes. It argues for a positive risk-based approach and a tool to help manage risk in the home, and applies these to a hypothetical end-of-life scenario. Recent findings: Historically, safety plans to consider risk management involved a culture of risk aversion supported by sometimes paternalistic motives intended to protect vulnerable clients. New findings in the literature engage in a process that respects the ethical principles underlying harm reduction philosophies. The literature also argues f...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: ETHICS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Irene Ying and Sally Bean Source Type: research

Withholding versus withdrawing treatment: artificial nutrition and hydration as a model
This article explores various cultural perspectives of withholding and withdrawing of life-sustaining treatment utilizing a case involving artificial nutrition and hydration (ANH) to guide ethical discussion. Recent findings: In the United States, there is a general consensus in the medical, ethical, and legal communities that the withholding and withdrawing of life-sustaining treatment are morally equivalent at the end of life. Despite this consensus, the withdrawal of treatment is still emotionally difficult, particularly with ANH. Recent literature challenges the evidence base that feeding tubes for people with advance...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: ETHICS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Irene Ying and Sally Bean Source Type: research

A systematic literature review on the ethics of palliative sedation: an update (2016)
Purpose of review: Palliative sedation has been the subject of intensive debate since its first appearance in 1990. In a 2010 review of palliative sedation, the following areas were identified as lacking in consensus: inconsistent terminology, its use in nonphysical suffering, the ongoing experience of distress, and concern that the practice of palliative sedation may hasten death. This review looks at the literature over the past 6 years and provides an update on these outstanding concerns. Recent findings: Good clinical guidelines and policies are still required to address issues of emotional distress and waylay concern...
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: ETHICS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Irene Ying and Sally Bean Source Type: research

No child is an island: ethical considerations in end-of-life care for children and their families
This article explores the challenges that may arise when there is disagreement between the child, the parents, and the healthcare providers about care at the end-of-life and provides suggestions to clinicians about how to help resolve these conflicts. (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: ETHICS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Irene Ying and Sally Bean Source Type: research

Whose value is it anyway? Clinical ethics in palliative and supportive care
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: ETHICS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Irene Ying and Sally Bean Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - August 5, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research

Current trends in the management of anaemia in solid tumours and haematological malignancies
This article reviews the pathophysiology of cancer-related anaemia, investigation of a cancer patient with anaemia as well as how anaemia impacts patients in terms of quality of life, disease-related outcomes and treatment choices. Recent findings: Different treatments for anaemia include transfusions, erythropoiesis-stimulating agents (ESA) and iron therapy. Within this context, we review the advantages and disadvantages concerning anaemia management in cancer patients as well as the risk–benefit ratio of different treatment choices, particularly the increased risk of thromboembolic events of ESAs and concern aroun...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

Cancer and chemotherapy-induced nausea and vomiting: a focus on olanzapine
Purpose of the review: The purpose of review is to critically present the evidence supporting the use of olanzapine, an atypical antipsychotic, as an antiemetic for cancer and chemotherapy-induced nausea and vomiting (CINV). Recent findings: Two phase III clinical studies demonstrated superior efficacy of olanzapine in comparison with the neurokinin-1 receptor antagonists (NK1RA) for substance P (aprepitant, fosaprepitant) in the prevention of nausea after highly emetogenic chemotherapy. Olanzapine is inexpensive and the replacement of NK1RA with olanzapine can reduce the costs of the prevention of CINV. The addition of o...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

Impact of chemotherapy on cancer-related fatigue and cytokines in 1312 patients: a systematic review of quantitative studies
Purpose of review: Cancer-related fatigue (CRF) is the most common psychosomatic distress experienced by cancer patients before, during and after chemotherapy. Its impact on functional status and Health Related Quality of Life is a great concern among patients, healthcare professionals and researchers. The primary objective of this systematic review is to determine whether the different chemotherapies affect the association of CRF with individual pro- and anti-inflammatory cytokines. The PRISMA statement guideline has been followed to systematically search and screen article from PubMed and Embase. Recent findings: This r...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

Toll-like receptors in the pathogenesis of chemotherapy-induced gastrointestinal toxicity
Purpose of review: Intestinal mucositis represents a common complication and dose-limiting toxicity of cancer chemotherapy. So far chemotherapy-induced intestinal mucositis remains poorly treatable resulting in significant morbidity and reduced quality of life in cancer patients. This review discusses recent insights into the pathophysiology of chemotherapy-induced intestinal mucositis. Novel mechanisms linking gut microbiota, host innate immunity and anticancer drug metabolism are highlighted. Recent findings: Gut microbiota may affect xenobiotic metabolism by direct and indirect mechanisms, critically modulating gut tox...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

Gastrointestinal toxicities of first and second-generation small molecule human epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

Advances in understanding and improving gastrointestinal symptoms during supportive and palliative care: a decade of progress
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: GASTROINTESTINAL SYMPTOMS: Edited by Rachel J. Gibson and Matthew A. Ciorba Source Type: research

What do monoamines do in pain modulation?
Purpose of review: Here, we give a topical overview of the ways in which brain processing can alter spinal pain transmission through descending control pathways, and how these change in pain states. We link preclinical findings on the transmitter systems involved and discuss how the monoamines, noradrenaline, 5-hydroxytryptamine (5-HT), and dopamine, can interact through inhibitory and excitatory pathways. Recent findings: Descending pathways control sensory events and the actions of the neurotransmitters noradrenaline and 5-HT in the dorsal horn of the spinal cord are chiefly implicated in nociception or antinociception ...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASE: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Autoantibodies and pain
Purpose of review: Over the last 20 years, several neurological conditions have been identified which appear to be caused directly by autoantibodies targeting receptors, ion channels and related proteins on neuronal or glial cells. Neuroimmune interactions are now accepted contributors to chronic pain conditions. Autoantibodies might be one such cause and here we highlight their potential role in pathological pain. Recent findings: Recent studies have given more weight to the idea that autoantibodies can be directly related to pain; this is suggested by the success of immunotherapy in patients and preclinical studies in a...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: PAIN: NON-MALIGNANT DISEASE: Edited by Anthony H. Dickenson and Kirsty Bannister Source Type: research

Opioids and chronic pain: using what we know to change what we do
Purpose of review: The review draws together firm conclusions about effectiveness and harms of prolonged opioid treatment and explores the complex nature of chronic pain. Recent findings: The literature may now explain why long-term opioid treatment has failed to live up to its late 20th century promise. An understanding of sources of bias in clinical trials has allowed a more detailed and accurate picture of the role of opioids in chronic pain to emerge and there is recognition that populations in clinical trials differ in very important ways to those given opioids in clinical practice. The prevalence of psychiatric and ...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: PAIN: CANCER: Edited by Anthony H. Dickenson and Paul Farquhar-Smith Source Type: research

Chemotherapy-induced painful neuropathy: pain-like behaviours in rodent models and their response to commonly used analgesics
We present an overview of dosing regimens to produce CIPN models and their phenotype of pain-like behaviours. In addition, we will discuss how potential, clinically available treatments affect pain-like behaviours in these rodent models, relating those effects to clinical trial data wherever possible. We have focussed on antidepressants, opioids, and gabapentinoids given their broad usage. Summary: The review outlines the latest description of the most-relevant rodent models of CIPN enabling comparison between chemotherapeutics, dosing regimen, rodent strain, and sex. Preclinical data support many of the recent suggestion...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: PAIN: CANCER: Edited by Anthony H. Dickenson and Paul Farquhar-Smith Source Type: research

Opioids and cancer: friend or foe?
Purpose of review: Most cancer patients experience pain and many will require opioids. However, the effects of opioids on cancer progression, metastasis, and recurrence is increasingly being questioned. There is evidence that opioids affect immune system function, angiogenesis, apoptosis, and invasion in a potentially deleterious manner. This review will examine the preclinical and clinical evidence. Recent findings: Recent clinical data have struggled to find robust evidence that opioids promote cancer progression. Although most study has involved morphine, differential effects of other opioids on immune function and can...
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: PAIN: CANCER: Edited by Anthony H. Dickenson and Paul Farquhar-Smith Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - April 29, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research

Erectile dysfunction after radical prostatectomy: prevalence, medical treatments, and psychosocial interventions
Purpose of review: This review will discuss erectile dysfunction in prostate cancer patients following radical prostatectomy . It will focus on the prevalence and current treatments for erectile dysfunction as well as the emotional impact of erectile dysfunction and the current psychosocial interventions designed to help patients cope with this side effect. Recent findings: Although there is a large discrepancy in prevalence rates of erectile dysfunction after radical prostatectomy, several recent studies have cited rates as high as 85%. The concept of ‘penile rehabilitation’ is now the standard of practice to...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Core principles of sexual health treatments in cancer for men
Purpose of review: The considerable prevalence of sexual health problems in men after cancer treatment coupled with the severity of impact and challenges to successful intervention make sexual dysfunction one of the most substantial health-related quality of life burdens in all of cancer survivorship. Surgeries, radiation therapies, and nontreatment (e.g., active surveillance) variously result in physical disfigurement, pain, and disruptions in physiological, psychological, and relational functioning. Although biomedical and psychological interventions have independently shown benefit, long-term, effective treatment for se...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Sexuality and aging: a focus on lesbian, gay, bisexual, and transgender (LGBT) needs in palliative and end of life care
This article reviews recent literature with considerations for future research. Summary: Sexuality and intimacy remain important for many people facing terminal illness. LGBT people face unique challenges with regard to sexuality during palliative care. Clinicians should work to avoid heteronormative stereotypes and focus on goals of care to enhance quality of life for all patients. (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Fertility preservation and cancer: challenges for adolescent and young adult patients
Purpose of review: With increasing survival rates, fertility is an important quality of life concern for many young cancer patients. There is a critical need for improvements in clinical care to ensure patients are well informed about infertility risks and fertility preservation options and to support them in their reproductive decision-making prior to treatment. Recent findings: Several barriers prevent fertility from being adequately addressed in the clinical context. Providers’ and patients’ incomplete or inaccurate understanding of infertility risks exacerbate patients’ reproductive concerns. For fem...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Can sexual outcomes be enhanced after cancer using online technology?
Purpose of review: The impact that cancer and its treatments can have on sexual functioning, sexual desire, and sexual arousal can be profound and many patients report significant unmet needs in relation to managing sexual difficulties. We reviewed the literature to understand the application of Internet-based technology in the delivery of psychosexual interventions, information provision, and support. Recent findings: Ten studies were identified that utilized Internet-based technology to deliver information, support, or psychosexual interventions designed to improve sexual outcomes, sexual distress, and quality of life o...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Emotional and sexual health in cancer: partner and relationship issues
Purpose of review: During the past decade, partners have been seen as integral to cancer survivors’ emotional and sexual well-being. The couple is viewed as the unit that copes with the impact of cancer on the most intimate aspects of the relationship, including sexuality. This review aims to provide an update on research reported in the past 2 years on partners and couples. Recent findings: Two thematic areas emerge: cancer-related distress management through increased communication, intimacy and building coping skills, and recovery of sexual intimacy. Observational studies have deepened our understanding of both a...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Sexual identity after breast cancer: sexuality, body image, and relationship repercussions
Purpose of review: Breast cancer treatment indelibly alters a woman's reproductive and sexual functioning, body integrity, and the ways in which she self-identifies as a sexual being. Improved understanding of how treatment affects these aspects of a woman's health, identity, and relationships is necessary to ameliorate the effectiveness with which these issues are addressed by healthcare providers. Recent findings: Women with breast cancer experience significantly greater rates of sexual dysfunction and poorer body image than do healthy women. Despite this reality, most breast cancer patients are dissatisfied with the am...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Maintaining intimacy for prostate cancer patients on androgen deprivation therapy
Purpose of review: Androgen deprivation therapy (ADT) causes erectile dysfunction and increases patients’ emotionality while diminishing their sexual interest. ADT has been linked to erosion of spousal bonds; however, this is not an invariant outcome. Understanding the factors that lead to these various outcomes may help couples deal with ADT. Recent findings: A subset of couples report that they became closer as a result of the patients going on ADT. Recent data suggest that what helps couples most is preemptive awareness of ADT's side-effects and congruence in how patients and their partners understand and accept ...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

How to ask and what to do: a guide for clinical inquiry and intervention regarding female sexual health after cancer
This study brings together a recently developed model for approaching clinical inquiry about sexual health with a brief problem checklist that has been adapted for use for female cancer survivors, as well as practical evidence-based strategies on how to address concerns identified on the checklist. Examples of patient education sheets are provided as well as strategies for building a referral network. Summary: By providing access to a concise and efficient tool for clinical inquiry, as well as targeted material resources and practical health-promoting strategies based on recent evidence-based findings, we hope to begin el...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Sexual health issues in cancer
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

The mechanisms of breathlessness in heart failure as the basis of therapy
Purpose of review: The review provides an overview of recent understanding in relation to the mechanisms relating to skeletal muscle and the sympathetic nervous system, and therapies for breathlessness which target these mechanisms. These are set in the context of established knowledge in this field. Recent findings: Despite strong evidence to support exercise training programmes, and recommendations in international guidelines, programmes are implemented poorly. Electrical stimulation appears to be a way of exercising people too frail to undertake a full exercise programme. There is evidence to support the use of opioids...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

An integrated review of interventions to improve psychological outcomes in caregivers of patients with heart failure
This article examines interventions aimed at improving psychological outcomes (e.g., caregiver burden, quality of life, anxiety, depression, perceived control, stress mastery, caregiver confidence and preparedness, and caregiver mastery) in family caregivers of patients with heart failure. Recent findings: Eight studies meeting the inclusion criteria were included in the review. The most common intervention involved psychoeducation facilitated by a nurse (6/8) and supplemented with a combination of follow-up face-to-face sessions (2/6), home visits (2/6), telephone calls (3/6), and telemonitoring (3/6). Two studies used a...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Transition to palliative care when transcatheter aortic valve implantation is not an option: opportunities and recommendations
Purpose of review: Transcatheter aortic valve implantation (TAVI) is the recommended treatment for most patients with symptomatic aortic stenosis at high surgical risk. However, TAVI may be clinically futile for patients who have multiple comorbidities and excessive frailty. This group benefits from transition to palliative care to maximize quality of life, improve symptoms, and ensure continuity of health services. We discuss the clinical determination of utility and futility, explore the current evidence guiding the integration of palliative care in procedure-focused cardiac programs, and outline recommendations for TAVI...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Providing palliative care for cardiovascular disease from a perspective of sociocultural diversity: a global view
This article discusses the available information on providing palliative care for cardiovascular disease (CVD) for individuals from culturally and linguistically diverse populations, and argues the need for cultural competence and awareness of healthcare providers. Recent findings: The burden of CVD is increasing globally and access to palliative care for individuals and populations is inconsistent and largely driven by policy, funding models, center-based expertise and local resources. Culture is an important social determinant of health and moderates health outcomes across the life trajectory. Along with approachability...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Integrating the complementary skills of palliative care and cardiology to develop care models supporting the needs of those with advanced heart failure
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Implantable cardioverter defibrillator deactivation: a precautionary approach to therapeutic equipoise?
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: CARDIAC AND CIRCULATORY PROBLEMS: Edited by James M. Beattie Source Type: research

Has pain management improved over the last decade in the Rapid Response Radiotherapy Program?
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research

Special 10th anniversary editorial: pain
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research

Special 10th Anniversary Editorial from Sam H. Ahmedzai
No abstract available (Source: Current Opinion in Supportive and Palliative Care)
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: Editorial Introductions Source Type: research