Fertility preservation in children and young adults with cancer
Purpose of review
The issue of fertility preservation has become increasingly relevant as survival rates of children with cancer exceeds 80% at 5 years. Fertility preservation options are being utilized alongside less gonadotoxic therapeutic regimens in the treatment of these patients. The purpose of this review is to summarize the recent advances in fertility preservation in the pediatric, adolescent, and young adult population.
Recent findings
Education research involves both patient and provider; to increase understanding on both sides for improved adoption of techniques and higher rates of posttreatment fe...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: HEMATOLOGY AND ONCOLOGY: Edited by Brigitte Widemann Source Type: research
Liquid biopsies in pediatric oncology: opportunities and obstacles
Purpose of review
Liquid biopsies have emerged as a noninvasive alternative to tissue biopsy with potential applications during all stages of pediatric oncology care. The purpose of this review is to provide a survey of pediatric cell-free DNA (cfDNA) studies, illustrate their potential applications in pediatric oncology, and to discuss technological challenges and approaches to overcome these hurdles.
Recent findings
Recent literature has demonstrated liquid biopsies’ ability to inform treatment selection at diagnosis, monitor clonal evolution during treatment, sensitively detect minimum residual disease foll...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: HEMATOLOGY AND ONCOLOGY: Edited by Brigitte Widemann Source Type: research
Inequality and child health: dynamic population health interventions
Purpose of review
Established social gradients across a wide range of child health issues including obesity, anxiety, infectious diseases, injuries, prematurity and low birth weight suggest that much illness is avoidable and there is an imperative to intervene in this whole of society issue. This review examines recent advances in understanding of the pathways to health and health inequalities and their application to interventions to improve health equity.
Recent findings
Children's health develops over the life course in ways that are profoundly influenced by their entire developmental ecosystem including indi...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Moving the needle on health inequities: principles and tactics for effective cross-sector population health networks
Purpose of review
To summarize elements of cross-sector population health networks to support systems and policy change to achieve equitable access to health services and healthy development opportunities for young children and families, allowing everyone to have a fair and just opportunity to be as healthy as possible.
Recent findings
The principles and tactics of Equity and Inclusion, Readiness, Joint Planning, Governance, and Data can guide cross-sector networks in effectively supporting communities in addressing health inequities. These principles are not linear or siloed, but rather, they overlap and reinfo...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Paediatric alternative payment models: emerging elements
Purpose of review
The aim of this study was to summarize emerging elements of paediatric alternative payment models (APMs), identify strategies to address barriers in implementing paediatric APMs and share policy approaches.
Recent findings
The unique health needs of children and adolescents must be considered as paediatric value-based care and APMs are developed. The longer time period for achieving cost savings, relatively few existing model tests and challenges with cross-sector data-sharing and pooled financing are barriers to the adoption of paediatric APMs. The Integrated Care for Kids (InCK) model and som...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
School-based health centers as a context to engage and serve communities
This article reviews findings on the perceived importance of school and community partnership. It also provides a critical review of the evidence base on impact on health, mental health, and education indicators.
Recent findings
Recent findings underscore the importance of SBHCs engaging the school and community to build trust while identifying and responding to needs. Engagement supports planning, implementing, and sustaining SBHCs. Studies of impact find that SBHCs increase participation in preventive and routine health and decrease emergency department utilization and hospitalization. However, additional research...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Addressing social determinants of health in pediatric health systems: balancing mission and financial sustainability
Purpose of review
With increasing recognition of the impact of poverty, racism and other social factors on child health, many pediatric health systems are undertaking interventions to address Social Determinants of Health (SDoH). This review summarizes these initiatives and recent developments in state and federal health policy impacting funding for these efforts.
Recent findings
Although the evidence defining optimal approaches to identifying and mitigating SDoH in children is still evolving, pediatric health systems are making significant investments in different initiatives to address SDoH. With limited reimb...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Clinical and public policy interventions to address food insecurity among children
This article describes the impacts of food insecurity (FI) on child health, outlines clinical and public policy interventions to mitigate FI in children, and defines new paradigms in population health to ameliorate the harmful effects of FI in children.
Recent findings
Rates of FI among children have dramatically increased with the onset of the COVID-19 pandemic, with particular adverse impact on low-income children. Population health innovations in screening, referral, and social service integration offer new opportunities to address FI.
Summary
Despite advances in clinical practice and public policy, FI rem...
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Editorial: New opportunities to create healthier generations of children
No abstract available (Source: Current Opinion in Pediatrics)
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: POPULATION HEALTH: Edited by Kara Odom Walker Source Type: research
Editorial introductions
No abstract available (Source: Current Opinion in Pediatrics)
Source: Current Opinion in Pediatrics - January 17, 2022 Category: Pediatrics Tags: EDITORIAL INTRODUCTIONS Source Type: research
Odyssey toward an understanding of acquired postinflammatory lentiginosis
Purpose of review
Acquired postinflammatory lentiginosis is a phenomenon that has been previously termed ‘induction of lentiginosis in assorted dermatoses’ or the ILIAD phenomenon.
Recent findings
Although some cases have been described as arising exclusively in those who applied topical calcineurin inhibitors (TCIs), other patients have presented with similar findings in other nonatopic disorders (contact dermatitis, psoriasis, lichen planus, focal dermal hypoplasia), and without antecedent use of TCIs.
Summary
Inflammatory skin disorders can produce localized areas of cutaneous lentiginosis, particu...
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: SPECIAL COMMENTARY Source Type: research
Cutaneous coronavirus disease 2019 in children: a clinical primer for diagnosis and treatment
Purpose of review
This review examines the global literature regarding rashes encountered in children and adults infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and aims to provide practicing pediatricians with an understanding of the relationship between instances of rashes and coronavirus disease 2019 (COVID-19) in children in order to effectively evaluate and treat patients.
Recent findings
The true incidence of cutaneous reactions in children infected with SARS-CoV-2 is not known. Children's immune systems differ from those of adults and rashes as a manifestation of immune response...
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: OFFICE PEDIATRICS: Edited by Henry H. Bernstein Source Type: research
Progress in understanding climate change's effects on children and youth
This article reviews the myriad health effects of climate change on children throughout their lives and discusses ways in which the general pediatrician can be an advocate for climate solutions.
Recent findings
Rising atmospheric temperatures, increased air pollution, and destabilized weather patterns all lead to adverse health outcomes for children and adverse obstetric outcomes. However, the impact of climate change is not evenly distributed. Children living in poverty are more likely to be adversely impacted by the changing climate.
Summary
Ongoing and emerging research suggests that children are particula...
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: OFFICE PEDIATRICS: Edited by Henry H. Bernstein Source Type: research
Catch it before it breaks!: managing metabolic bone disease of prematurity
We present a review of the risk factors, recent screening methods, diagnosis and management of this prevalent, clinically relevant diagnosis, as well as propose a protocol for the early screening and management of this silent disease. (Source: Current Opinion in Pediatrics)
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: OFFICE PEDIATRICS: Edited by Henry H. Bernstein Source Type: research
New primary immunodeficiencies 2021 context and future
Purpose of review
Primary immunodeficiency diseases (PIDs), also called inborn errors of immunity (IEI), are genetic disorders classically characterized by an increased susceptibility to infection and/or disruption in the regulation of an immunologic pathway. This review summarizes and highlights the new IEI disorders in the IUIS 2019 report and 2020 interim report and discusses the directions for the future management of PIDs.
Recent findings
Since 2017, the International Union of Immunologic Societies (IUIS) IEI committee has updated the IUIS classification of IEIs with 88 new gene defects and 75 new immune di...
Source: Current Opinion in Pediatrics - November 10, 2021 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research
