Conditionally unutilized proteins and their profound effects on growth and adaptation across microbial species
Curr Opin Microbiol. 2023 Aug 23;75:102366. doi: 10.1016/j.mib.2023.102366. Online ahead of print.ABSTRACTProtein synthesis is an important determinant of microbial growth and response that demands a high amount of metabolic and biosynthetic resources. Despite these costs, microbial species from different taxa and habitats massively synthesize proteins that are not utilized in the conditions they currently experience. Based on resource allocation models, recent studies have begun to reconcile the costs and benefits of these conditionally unutilized proteins (CUPs) in the context of varying environmental conditions. Such ma...
Source: Current Opinion in Microbiology - August 25, 2023 Category: Microbiology Authors: Rohan Balakrishnan Jonas Cremer Source Type: research
Fungal pathogens and COVID-19
Curr Opin Microbiol. 2023 Aug 23;75:102365. doi: 10.1016/j.mib.2023.102365. Online ahead of print.ABSTRACTCOVID-19 pandemic highlighted the complications of secondary fungal infections that occurred globally in severe cases of coronavirus disease managed in the intensive care units. Furthermore, varied underlying host factors, such as preexisting immunosuppression, the use of immunomodulatory agents, and invasive procedures predisposing lung tissues to fungal colonization and proliferation, caused increased susceptibility to fungal infections in COVID-19 patient populations. These invasive fungal infections directly impact...
Source: Current Opinion in Microbiology - August 25, 2023 Category: Microbiology Authors: Ashutosh Singh Amtoj Kaur Anuradha Chowdhary Source Type: research
Conditionally unutilized proteins and their profound effects on growth and adaptation across microbial species
Curr Opin Microbiol. 2023 Aug 23;75:102366. doi: 10.1016/j.mib.2023.102366. Online ahead of print.ABSTRACTProtein synthesis is an important determinant of microbial growth and response that demands a high amount of metabolic and biosynthetic resources. Despite these costs, microbial species from different taxa and habitats massively synthesize proteins that are not utilized in the conditions they currently experience. Based on resource allocation models, recent studies have begun to reconcile the costs and benefits of these conditionally unutilized proteins (CUPs) in the context of varying environmental conditions. Such ma...
Source: Current Opinion in Microbiology - August 25, 2023 Category: Microbiology Authors: Rohan Balakrishnan Jonas Cremer Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
An update on the current understanding of the infant skin microbiome and research challenges
Curr Opin Microbiol. 2023 Aug 14;75:102364. doi: 10.1016/j.mib.2023.102364. Online ahead of print.ABSTRACTMultiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecosystems impacting health. This review provides an update on methods used to profile the skin microbiome and how this is helping enhance our understanding of infant skin microbial communities, including factors that influence composition and disease risk. We also provide insights into new interventional studies and treatments in this area. However, it is apparent that there are still research bottlene...
Source: Current Opinion in Microbiology - August 16, 2023 Category: Microbiology Authors: Iliana R Serghiou Mark A Webber Lindsay J Hall Source Type: research
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Curr Opin Microbiol. 2023 Aug 2;75:102363. doi: 10.1016/j.mib.2023.102363. Online ahead of print.ABSTRACTAnaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic ne...
Source: Current Opinion in Microbiology - August 5, 2023 Category: Microbiology Authors: Arianna Basile Guido Zampieri Adam Kovalovszki Behzad Karkaria Laura Treu Kiran Raosaheb Patil Stefano Campanaro Source Type: research
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Curr Opin Microbiol. 2023 Aug 2;75:102363. doi: 10.1016/j.mib.2023.102363. Online ahead of print.ABSTRACTAnaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic ne...
Source: Current Opinion in Microbiology - August 5, 2023 Category: Microbiology Authors: Arianna Basile Guido Zampieri Adam Kovalovszki Behzad Karkaria Laura Treu Kiran Raosaheb Patil Stefano Campanaro Source Type: research
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Curr Opin Microbiol. 2023 Aug 2;75:102363. doi: 10.1016/j.mib.2023.102363. Online ahead of print.ABSTRACTAnaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic ne...
Source: Current Opinion in Microbiology - August 5, 2023 Category: Microbiology Authors: Arianna Basile Guido Zampieri Adam Kovalovszki Behzad Karkaria Laura Treu Kiran Raosaheb Patil Stefano Campanaro Source Type: research
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Curr Opin Microbiol. 2023 Aug 2;75:102363. doi: 10.1016/j.mib.2023.102363. Online ahead of print.ABSTRACTAnaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic ne...
Source: Current Opinion in Microbiology - August 5, 2023 Category: Microbiology Authors: Arianna Basile Guido Zampieri Adam Kovalovszki Behzad Karkaria Laura Treu Kiran Raosaheb Patil Stefano Campanaro Source Type: research
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Curr Opin Microbiol. 2023 Aug 2;75:102363. doi: 10.1016/j.mib.2023.102363. Online ahead of print.ABSTRACTAnaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic ne...
Source: Current Opinion in Microbiology - August 5, 2023 Category: Microbiology Authors: Arianna Basile Guido Zampieri Adam Kovalovszki Behzad Karkaria Laura Treu Kiran Raosaheb Patil Stefano Campanaro Source Type: research
