Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Dec;85:102398. doi: 10.1016/j.coi.2023.102398. Epub 2023 Nov 16.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or direct muc...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Recent advances in enterotoxin vaccine adjuvants
Curr Opin Immunol. 2023 Nov 15;85:102398. doi: 10.1016/j.coi.2023.102398. Online ahead of print.ABSTRACTEnterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of cholera vaccines, however, these proteins have yet to be included in any currently licensed vaccines. They include molecules derived from the bacterial toxins of Vibrio cholerae, cholera toxin, or Escherichia coli, heat-labile toxin, such as detoxified mutants or subunits. This class of adjuvants is distinguished by their delivery possibilities, which include parenteral injection, skin applications, or di...
Source: Current Opinion in Immunology - November 17, 2023 Category: Allergy & Immunology Authors: Jessica W Crothers Elizabeth B Norton Source Type: research
Animal models of shigellosis: a historical overview
Curr Opin Immunol. 2023 Nov 10;85:102399. doi: 10.1016/j.coi.2023.102399. Online ahead of print.ABSTRACTShigella spp. are major causative agents of bacillary dysentery, a severe enteric disease characterized by destruction and inflammation of the colonic epithelium accompanied by acute diarrhea, fever, and abdominal pain. Although antibiotics have traditionally been effective, the prevalence of multidrug-resistant strains is increasing, stressing the urgent need for a vaccine. The human-specific nature of shigellosis and the absence of a dependable animal model have posed significant obstacles in understanding Shigella pat...
Source: Current Opinion in Immunology - November 12, 2023 Category: Allergy & Immunology Authors: No émie Alphonse Charlotte Odendall Source Type: research
Animal models of shigellosis: a historical overview
Curr Opin Immunol. 2023 Nov 10;85:102399. doi: 10.1016/j.coi.2023.102399. Online ahead of print.ABSTRACTShigella spp. are major causative agents of bacillary dysentery, a severe enteric disease characterized by destruction and inflammation of the colonic epithelium accompanied by acute diarrhea, fever, and abdominal pain. Although antibiotics have traditionally been effective, the prevalence of multidrug-resistant strains is increasing, stressing the urgent need for a vaccine. The human-specific nature of shigellosis and the absence of a dependable animal model have posed significant obstacles in understanding Shigella pat...
Source: Current Opinion in Immunology - November 12, 2023 Category: Allergy & Immunology Authors: No émie Alphonse Charlotte Odendall Source Type: research
