Current Opinion in Endocrinology, Diabetes and Obesity This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Editorial: Dyslipidaemia and cardiometabolic health: springboard for an emerging medical specialty?
No abstract available (Source: Current Opinion in Endocrinology, Diabetes and Obesity)
Source: Current Opinion in Endocrinology, Diabetes and Obesity - March 2, 2021 Category: Endocrinology Tags: LIPIDS: Edited by Gerald F. Watts Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Endocrinology, Diabetes and Obesity)
Source: Current Opinion in Endocrinology, Diabetes and Obesity - March 2, 2021 Category: Endocrinology Tags: EDITORIAL INTRODUCTIONS Source Type: research

Adrenal insufficiency updates in children
Purpose of review The current article will review the newest diagnostic tools, genetic causes, and treatment of adrenal insufficiency in children. Recent findings It is common practice to perform an adrenocorticotropin hormone (ACTH) stimulation test when adrenal insufficiency is suspected. The indications for use of a high-dose or low-dose of synthetic ACTH in children have been refined. In addition, newer studies propose adding 15 and 30-min serum or salivary cortisol levels to the low-dose ACTH stimulation test to correctly identify adrenal insufficiency. Recent identification of genetic mutations in children...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: GROWTH AND DEVELOPMENT: Edited by Lynne L. Levitsky Source Type: research

Growth, body composition, and endocrine issues in Williams syndrome
Purpose of review Williams syndrome is a multisystem disorder caused by a microdeletion on chromosome 7q. Throughout infancy, childhood, and adulthood, abnormalities in body composition and in multiple endocrine axes may arise for individuals with Williams syndrome. This review describes the current literature regarding growth, body composition, and endocrine issues in Williams syndrome with recommendations for surveillance and management by the endocrinologist, geneticist, or primary care physician. Recent findings In addition to known abnormalities in stature, calcium metabolism, and thyroid function, individu...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: GROWTH AND DEVELOPMENT: Edited by Lynne L. Levitsky Source Type: research

Pharmacotherapy in pediatric obesity: current evidence and landscape
Purpose of review Childhood obesity is escalating globally. Lifestyle and behavioral changes, which are the frequently used interventions in clinical practice, lead to only modest improvements in children with established obesity. Bariatric surgery is currently the most effective obesity treatment but has very limited utilization in pediatric obesity and is preferentially used for children with worsening comorbidities. There exists a massive treatment gap for children suffering with obesity especially after the failure of lifestyle modifications. Pharmacotherapy that is an established management tool in adults is very ...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: GROWTH AND DEVELOPMENT: Edited by Lynne L. Levitsky Source Type: research

Adult obesity and its complications: a pediatric disease?
Purpose of review Approximately 2.6 million people die each year secondary to obesity related diseases. The risk of developing serious comorbidities depends on the age of onset as well as duration of obesity. In this review, we discuss trends in BMI trajectories from early childhood to adulthood with latest evidence on comorbidities in adulthood stemming from pediatric obesity and benefits of early intervention and treatment in childhood obesity. Recent findings Childhood obesity poses high risk of metabolic and cardiovascular disorders like type 2 diabetes, hypertension, atherosclerosis, coronary artery disease...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: GROWTH AND DEVELOPMENT: Edited by Lynne L. Levitsky Source Type: research

Editorial: Growth and development in a time of coronavirus
No abstract available (Source: Current Opinion in Endocrinology, Diabetes and Obesity)
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: GROWTH AND DEVELOPMENT: Edited by Lynne L. Levitsky Source Type: research

Coronavirus disease 2019 and type 1 diabetes mellitus
Purpose of review Type 2 diabetes (T2DM) is a major comorbidity of coronavirus disease 2019 (COVID-19) but less is known about COVID-19 and type 1 diabetes (T1DM). Thus, our goal was to review the literature on COVID and T1DM. Recent findings We identified 21 reports focusing on COVID-19 infections among patients with preexisting T1DM (n = 7), incident T1DM presentations during the COVID-19 quarantine (n = 6), and outpatient management of T1DM during the COVID-19 quarantine (n = 8). These studies showed that patients with preexisting T1DM and COVID-19 infection often present with hyperglycemia and/or...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Pregnancy and type 1 diabetes: updates on technology and treatment
Purpose of review The goal of this article is to review recent research of technology use, including insulin pumps, continuous glucose monitors, and smartpens, for pregnant women with preexisting type 1 diabetes. Recent findings Recent research shows that there may be benefits from technology use in type 1 diabetes pregnancies given the changes in insulin sensitivity throughout the span of pregnancy as well as allowing for more monitoring to allow for sooner titration of insulin doses. Summary There may be utility in incorporation of technology during pregnancy with appropriate medical guidance. Additiona...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Telehealth in type 1 diabetes
Purpose of review The role of telehealth in the care of people with type 1 diabetes (T1D) has expanded dramatically during the coronavirus pandemic, and is expected to remain a major care delivery modality going forward. This review explores the landscape of recent evidence for telehealth in T1D care. Recent findings Telemedicine for routine T1D care has shown equivalence to standard in-person care, with respect to glycemic control, while also increasing access, convenience, and satisfaction. Telehealth use promotes increased engagement of adolescents with T1D. Telehealth platforms have successfully been used in...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Hospital care: improving outcomes in type 1 diabetes
Purpose of review Caring for patients with type 1 diabetes (T1D) in the hospital presents unique challenges. This review provides an update on significant issues relevant to the inpatient management of T1D. Topics include trends in diabetic ketoacidosis (DKA), hypoglycemia, and adapting ambulatory technologies for inpatient use. Recent findings Rates of DKA in the United States are rising. Although socioeconomic status, health insurance coverage, and hemoglobin A1c are persistently associated with DKA in individuals with T1D, newer risk factors have also emerged. These include the off-label use of sodium-glucose...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Adjunctive therapies in type 1 diabetes mellitus
Purpose of review Insulin is the mainstay of treatment in people living with type 1 diabetes mellitus due to an immune-mediated loss of beta cells. Yet despite advances in insulin therapy and other technological advances, glycemic control remains difficult to achieve. Therefore, we aim to highlight risks and benefits of adjunctive therapies that may improve type 1 diabetes care. Recent findings We identified studies assessing clinical outcomes of adjunctive therapies that are both Food and Drug Administration (FDA)-approved and off-label in type 1 diabetes. Adjunctive therapies reviewed included metformin, praml...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Advances in newer basal and bolus insulins: impact on type 1 diabetes
Purpose of review Insulin administration is vitally important to maintain a good glycaemic control in people with type 1 diabetes mellitus (T1DM). The purpose of this review is to give a clinically relevant overview of the newer basal and bolus insulin analogues and to highlight their practicalities of use and advantages in specific categories of patients with T1DM. Recent findings Second-generation rapid-acting insulin analogues (i.e. faster insulin aspart and ultrarapid-acting lispro) have shown to be safe, efficient and superior in controlling postprandial plasma glucose levels without an increase in hypoglyc...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: DIABETES AND THE ENDOCRINE PANCREAS I: Edited by Matthew Freeby Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Endocrinology, Diabetes and Obesity)
Source: Current Opinion in Endocrinology, Diabetes and Obesity - December 26, 2020 Category: Endocrinology Tags: EDITORIAL INTRODUCTIONS Source Type: research

Leydig stem cells and future therapies for hypogonadism
Purpose of review In this review, we outline the most recent advances in the development of Leydig stem cells (LSCs) and summarize the current and upcoming treatments for hypogonadism. Recent findings In-vitro and in-vivo studies show that inducing stem cells to differentiate into testosterone-producing adult Leydig cells is possible. In addition, LSCs can be grafted with Sertoli cells to increase testosterone levels in vivo. This therapy causes minimal effects on luteinizing hormone and follicle stimulating hormone levels. Novel therapies for hypogonadism include varying methods of testosterone delivery such as intra...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - October 27, 2020 Category: Endocrinology Tags: ANDROGENS: Edited by Katherine L. Rotker Source Type: research