Current Neurology and Neuroscience Reports 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Updates in Functional Movement Disorders: from Pathophysiology to Treatment Advances
AbstractPurpose of ReviewThis review discusses advances in functional movement disorders (FMD) over the past 3 years, with a focus on risk factors, diagnosis, pathophysiology, neuroimaging studies, and treatment.Recent FindingsThe past decade has brought a revived interest in functional movement disorders, with a growing number of studies exploring pathophysiological mechanisms. Here, we review recent studies demonstrating changes in attention, emotional and sensorimotor function in FMD. Through international collaborative efforts, progress has been made in defining biomarkers and outcome measures, an important prerequis...
Source: Current Neurology and Neuroscience Reports - April 19, 2022 Category: Neuroscience Source Type: research
Utilizing Implementation Science to Bridge Cerebrovascular Health Disparities: a Local to Global Perspective
AbstractPurpose of ReviewStroke is a prime example of a medical disorder whose incidence, prevalence, and outcomes are strongly characterized by health disparities across the globe. This scoping literature review seeks to depict how implementation science could be utilized to advance health equity in the prevention, acute treatment, and post-acute management of stroke in the underserved regions of high-income countries as well as in all low-income countries.Recent FindingsA major reason for the persisting and widening cerebrovascular disease disparities is that evidence-based stroke prevention and treatment interventions h...
Source: Current Neurology and Neuroscience Reports - April 6, 2022 Category: Neuroscience Source Type: research
Sleep Dysfunction and Grey Matter Volume
This article reviews recent findings on GM structure in various sleep disorders and possible causes of disturbed sleep and discusses the future perspectives.Recent FindingsAt present, research on the effect of GM volume changes in specific brain areas on the pathogenesis of sleep disturbances is incomplete. It remains unknown if the GM thickness reduction in patients with REM sleep behaviour disorder, obstructive sleep apnea, restless legs syndrome, and insomnia is due to complex disease presentation or direct response to disturbed sleep. Additionally, many VBM studies have yielded inconsistent results showing either reduc...
Source: Current Neurology and Neuroscience Reports - April 2, 2022 Category: Neuroscience Source Type: research
New Options (or not) for Treatment of Idiopathic Intracranial Hypertension
This article reviews the recent advances and research on the treatment of IIH.Recent findingsVenous sinus stenting (VSS) is now performed in many experienced centers, and there is growing interest in bariatric surgery as a treatment modality. Newly approved anti-obesity drugs are showing effectiveness in weight loss, and novel targeted disease-modifying IIH therapies are being explored.SummaryFurther evaluation of these novel therapeutic strategies as well as studies exploring the use of anti-obesity drugs in IIH is needed. While VSS is gaining popularity due to its efficacy and low complication rate, there is insufficient...
Source: Current Neurology and Neuroscience Reports - April 1, 2022 Category: Neuroscience Source Type: research
Epileptogenesis in Common Parasitic Infections
AbstractPurpose of the reviewNeurocysticercosis (NCC) has been well recognized as a leading cause of epilepsy. More recently, studies of other parasitic diseases such as cerebral malaria (CM) and onchocerciasis are yielding novel insights into the pathogenesis of parasite-associated epilepsy. We compare the clinical and electrophysiological findings in epilepsy associated with these highly prevalent para sites and discuss the mechanisms involved in epileptogenesis.Recent FindingsElectrophysiological and imaging biomarkers continue to emerge, and individuals who are at-risk of developing parasite-associated epilepsies a...
Source: Current Neurology and Neuroscience Reports - April 1, 2022 Category: Neuroscience Source Type: research
Management of Functional Vision Disorders
AbstractPurpose of ReviewThe purpose of this review is to summarize current approaches to management of functional vision disorder (FVD).Recent FindingsSeveral retrospective studies of FVD in both adults and children have shed light on the range of outcomes and the prevalence of psychosocial stressors among FVD patients. While the first line of treatment for FVD is reassurance and education, recent case reports highlight the use of additional treatment modalities including psychotherapy, hypnosis, and transcranial magnetic stimulation in specific cases.SummaryAlthough the epidemiology and diagnosis of functional vision dis...
Source: Current Neurology and Neuroscience Reports - April 1, 2022 Category: Neuroscience Source Type: research
Diagnostic Error in Neuro-ophthalmology: Avenues to Improve
AbstractPurpose of ReviewTo highlight potential avenues to reduce preventable diagnostic error of neuro-ophthalmic conditions and avoid patient harm.Recent FindingsRecent prospective studies and studies of patient harm have advanced our understanding. Additionally, recent studies of fundus photography, telemedicine, and artificial intelligence highlight potential avenues for diagnostic improvement.SummaryDiagnostic error of neuro-ophthalmic conditions can often be traced to failure to gather an adequate history, perform a complete physical exam, obtain adequate/appropriate neuroimaging, and generate a complete, appropriate...
Source: Current Neurology and Neuroscience Reports - April 1, 2022 Category: Neuroscience Source Type: research
The clinical approach to the identification of higher-order visual dysfunction in neurodegenerative disease
AbstractPurpose of ReviewThis review is intended to assist the reader in gaining the knowledge and skills necessary for the recognition and assessment of higher-order visual dysfunction due to neurodegenerative diseases including Alzheimer ’s disease, dementia with Lewy bodies, Parkinson’s dementia, corticobasal degeneration, Creutzfeldt–Jakob disease, and the posterior cortical atrophy syndrome. Clinical problem-solving and pattern recognition must be developed and practiced to accurately diagnosis disturbances of higher-order visual function, and knowledge of higher-order visual brain regions and their visual syndr...
Source: Current Neurology and Neuroscience Reports - April 1, 2022 Category: Neuroscience Source Type: research
New Options (or not) for Treatment of Idiopathic Intracranial Hypertension
This article reviews the recent advances and research on the treatment of IIH.Recent findingsVenous sinus stenting (VSS) is now performed in many experienced centers, and there is growing interest in bariatric surgery as a treatment modality. Newly approved anti-obesity drugs are showing effectiveness in weight loss, and novel targeted disease-modifying IIH therapies are being explored.SummaryFurther evaluation of these novel therapeutic strategies as well as studies exploring the use of anti-obesity drugs in IIH is needed. While VSS is gaining popularity due to its efficacy and low complication rate, there is insufficient...
Source: Current Neurology and Neuroscience Reports - March 25, 2022 Category: Neuroscience Source Type: research
Blood Pressure in Acute Stroke and Secondary Stroke Prevention
This article reviews current guidelines for early management of blood pressure (BP) and highlights the findings of recent investigative works.Recent FindingsIntensive blood pressure reduction after receiving alteplase has not been shown to improve outcomes. Patients with large vessel occlusions may benefit from lower blood pressure targets post-intervention. Retrospective analyses of large intracerebral hemorrhage trials suggest that specific subgroups of patients may disproportionately benefit from or be harmed by intensive BP reduction. Robust data for management of blood pressure in subarachnoid hemorrhage patients is l...
Source: Current Neurology and Neuroscience Reports - March 25, 2022 Category: Neuroscience Source Type: research
Epileptogenesis in Common Parasitic Infections
AbstractPurpose of the reviewNeurocysticercosis (NCC) has been well recognized as a leading cause of epilepsy. More recently, studies of other parasitic diseases such as cerebral malaria (CM) and onchocerciasis are yielding novel insights into the pathogenesis of parasite-associated epilepsy. We compare the clinical and electrophysiological findings in epilepsy associated with these highly prevalent para sites and discuss the mechanisms involved in epileptogenesis.Recent FindingsElectrophysiological and imaging biomarkers continue to emerge, and individuals who are at-risk of developing parasite-associated epilepsies a...
Source: Current Neurology and Neuroscience Reports - March 25, 2022 Category: Neuroscience Source Type: research
Management of Functional Vision Disorders
AbstractPurpose of ReviewThe purpose of this review is to summarize current approaches to management of functional vision disorder (FVD).Recent FindingsSeveral retrospective studies of FVD in both adults and children have shed light on the range of outcomes and the prevalence of psychosocial stressors among FVD patients. While the first line of treatment for FVD is reassurance and education, recent case reports highlight the use of additional treatment modalities including psychotherapy, hypnosis, and transcranial magnetic stimulation in specific cases.SummaryAlthough the epidemiology and diagnosis of functional vision dis...
Source: Current Neurology and Neuroscience Reports - March 23, 2022 Category: Neuroscience Source Type: research
Diagnostic Error in Neuro-ophthalmology: Avenues to Improve
AbstractPurpose of ReviewTo highlight potential avenues to reduce preventable diagnostic error of neuro-ophthalmic conditions and avoid patient harm.Recent FindingsRecent prospective studies and studies of patient harm have advanced our understanding. Additionally, recent studies of fundus photography, telemedicine, and artificial intelligence highlight potential avenues for diagnostic improvement.SummaryDiagnostic error of neuro-ophthalmic conditions can often be traced to failure to gather an adequate history, perform a complete physical exam, obtain adequate/appropriate neuroimaging, and generate a complete, appropriate...
Source: Current Neurology and Neuroscience Reports - March 23, 2022 Category: Neuroscience Source Type: research
The clinical approach to the identification of higher-order visual dysfunction in neurodegenerative disease
AbstractPurpose of ReviewThis review is intended to assist the reader in gaining the knowledge and skills necessary for the recognition and assessment of higher-order visual dysfunction due to neurodegenerative diseases including Alzheimer ’s disease, dementia with Lewy bodies, Parkinson’s dementia, corticobasal degeneration, Creutzfeldt–Jakob disease, and the posterior cortical atrophy syndrome. Clinical problem-solving and pattern recognition must be developed and practiced to accurately diagnosis disturbances of higher-order visual function, and knowledge of higher-order visual brain regions and their visual syndr...
Source: Current Neurology and Neuroscience Reports - March 23, 2022 Category: Neuroscience Source Type: research
