Epigenetic Diversity Underlying Seasonal and Annual Variations in Brown Planthopper (BPH) Populations as Revealed by Methylation- sensitive Restriction Assay
CONCLUSION: Screening field-collected BPH populations revealed the presence of previously unreported epigenetic polymorphisms and provided a platform for future studies aimed at investigating their significance for BPH. Furthermore, these findings can form the basis for understanding the contribution(s) of DNA methylation in providing phenotypic plasticity to BPH.PMID:38327650 | PMC:PMC10845068 | DOI:10.2174/0113892029276542231205065843 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Ayushi Gupta Suresh Nair Source Type: research

Aberrant Expressions of < em > PSMD14 < /em > in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
CONCLUSION: In conclusion, our research showed that PSMD14 might be related to recurrence in HCC patients, and the expression of PSMD14 in tumor tissue might be a potential prognostic biomarker after tumor resection in HCC patients.PMID:38327651 | PMC:PMC10845065 | DOI:10.2174/0113892029277262231108105441 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Yi-Mei Xiong Fang Zhou Jia-Wen Zhou Fei Liu Si-Qi Zhou Bo Li Zhong-Jian Liu Yang Qin Source Type: research

Identification of Two Novel Pathogenic Variants of the < em > ATM < /em > Gene in the Iranian-Azeri Turkish Ethnic Group by Applying Whole Exome Sequencing
CONCLUSION: Genetic analysis of three unrelated families with ATM-related disorders discovered two novel pathogenic variants. A homozygous missense pathogenic variant was identified in a woman with bi-lateral breast cancer, and a synonymous but pathogenic variant was found in a family with a history of different cancers.PMID:38327652 | PMC:PMC10845066 | DOI:10.2174/0113892029268949231104165301 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Amir-Reza Dalal Amandi Neda Jabbarpour Shadi Shiva Mortaza Bonyadi Source Type: research

Oxford Nanopore Technology and its Application in Liquid Biopsies
Curr Genomics. 2023 Dec 28;24(6):337-344. doi: 10.2174/0113892029286632231127055733.ABSTRACTAdvanced medical technologies are transforming the future of healthcare, in particular, the screening and detection of molecular-genetic changes in patients suspected of having a neoplasm. They are based on the assumption that neoplasms release small amounts of various neoplasm-specific molecules, such as tumor DNA, called circulating DNA (cirDNA), into the extracellular space and subsequently into the blood. The detection of tumor-specific molecules and specific molecular changes in body fluids in a noninvasive or minimally invasiv...
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Mariya Levkova Trifon Chervenkov Lyudmila Angelova Deyan Dzenkov Source Type: research

Epigenetic Diversity Underlying Seasonal and Annual Variations in Brown Planthopper (BPH) Populations as Revealed by Methylation- sensitive Restriction Assay
CONCLUSION: Screening field-collected BPH populations revealed the presence of previously unreported epigenetic polymorphisms and provided a platform for future studies aimed at investigating their significance for BPH. Furthermore, these findings can form the basis for understanding the contribution(s) of DNA methylation in providing phenotypic plasticity to BPH.PMID:38327650 | PMC:PMC10845068 | DOI:10.2174/0113892029276542231205065843 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Ayushi Gupta Suresh Nair Source Type: research

Aberrant Expressions of < em > PSMD14 < /em > in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
CONCLUSION: In conclusion, our research showed that PSMD14 might be related to recurrence in HCC patients, and the expression of PSMD14 in tumor tissue might be a potential prognostic biomarker after tumor resection in HCC patients.PMID:38327651 | PMC:PMC10845065 | DOI:10.2174/0113892029277262231108105441 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Yi-Mei Xiong Fang Zhou Jia-Wen Zhou Fei Liu Si-Qi Zhou Bo Li Zhong-Jian Liu Yang Qin Source Type: research

Identification of Two Novel Pathogenic Variants of the < em > ATM < /em > Gene in the Iranian-Azeri Turkish Ethnic Group by Applying Whole Exome Sequencing
CONCLUSION: Genetic analysis of three unrelated families with ATM-related disorders discovered two novel pathogenic variants. A homozygous missense pathogenic variant was identified in a woman with bi-lateral breast cancer, and a synonymous but pathogenic variant was found in a family with a history of different cancers.PMID:38327652 | PMC:PMC10845066 | DOI:10.2174/0113892029268949231104165301 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Amir-Reza Dalal Amandi Neda Jabbarpour Shadi Shiva Mortaza Bonyadi Source Type: research

Oxford Nanopore Technology and its Application in Liquid Biopsies
Curr Genomics. 2023 Dec 28;24(6):337-344. doi: 10.2174/0113892029286632231127055733.ABSTRACTAdvanced medical technologies are transforming the future of healthcare, in particular, the screening and detection of molecular-genetic changes in patients suspected of having a neoplasm. They are based on the assumption that neoplasms release small amounts of various neoplasm-specific molecules, such as tumor DNA, called circulating DNA (cirDNA), into the extracellular space and subsequently into the blood. The detection of tumor-specific molecules and specific molecular changes in body fluids in a noninvasive or minimally invasiv...
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Mariya Levkova Trifon Chervenkov Lyudmila Angelova Deyan Dzenkov Source Type: research

Epigenetic Diversity Underlying Seasonal and Annual Variations in Brown Planthopper (BPH) Populations as Revealed by Methylation- sensitive Restriction Assay
CONCLUSION: Screening field-collected BPH populations revealed the presence of previously unreported epigenetic polymorphisms and provided a platform for future studies aimed at investigating their significance for BPH. Furthermore, these findings can form the basis for understanding the contribution(s) of DNA methylation in providing phenotypic plasticity to BPH.PMID:38327650 | PMC:PMC10845068 | DOI:10.2174/0113892029276542231205065843 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Ayushi Gupta Suresh Nair Source Type: research

Aberrant Expressions of < em > PSMD14 < /em > in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
CONCLUSION: In conclusion, our research showed that PSMD14 might be related to recurrence in HCC patients, and the expression of PSMD14 in tumor tissue might be a potential prognostic biomarker after tumor resection in HCC patients.PMID:38327651 | PMC:PMC10845065 | DOI:10.2174/0113892029277262231108105441 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Yi-Mei Xiong Fang Zhou Jia-Wen Zhou Fei Liu Si-Qi Zhou Bo Li Zhong-Jian Liu Yang Qin Source Type: research

Identification of Two Novel Pathogenic Variants of the < em > ATM < /em > Gene in the Iranian-Azeri Turkish Ethnic Group by Applying Whole Exome Sequencing
CONCLUSION: Genetic analysis of three unrelated families with ATM-related disorders discovered two novel pathogenic variants. A homozygous missense pathogenic variant was identified in a woman with bi-lateral breast cancer, and a synonymous but pathogenic variant was found in a family with a history of different cancers.PMID:38327652 | PMC:PMC10845066 | DOI:10.2174/0113892029268949231104165301 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Amir-Reza Dalal Amandi Neda Jabbarpour Shadi Shiva Mortaza Bonyadi Source Type: research

Oxford Nanopore Technology and its Application in Liquid Biopsies
Curr Genomics. 2023 Dec 28;24(6):337-344. doi: 10.2174/0113892029286632231127055733.ABSTRACTAdvanced medical technologies are transforming the future of healthcare, in particular, the screening and detection of molecular-genetic changes in patients suspected of having a neoplasm. They are based on the assumption that neoplasms release small amounts of various neoplasm-specific molecules, such as tumor DNA, called circulating DNA (cirDNA), into the extracellular space and subsequently into the blood. The detection of tumor-specific molecules and specific molecular changes in body fluids in a noninvasive or minimally invasiv...
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Mariya Levkova Trifon Chervenkov Lyudmila Angelova Deyan Dzenkov Source Type: research

Epigenetic Diversity Underlying Seasonal and Annual Variations in Brown Planthopper (BPH) Populations as Revealed by Methylation- sensitive Restriction Assay
CONCLUSION: Screening field-collected BPH populations revealed the presence of previously unreported epigenetic polymorphisms and provided a platform for future studies aimed at investigating their significance for BPH. Furthermore, these findings can form the basis for understanding the contribution(s) of DNA methylation in providing phenotypic plasticity to BPH.PMID:38327650 | PMC:PMC10845068 | DOI:10.2174/0113892029276542231205065843 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Ayushi Gupta Suresh Nair Source Type: research

Aberrant Expressions of < em > PSMD14 < /em > in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
CONCLUSION: In conclusion, our research showed that PSMD14 might be related to recurrence in HCC patients, and the expression of PSMD14 in tumor tissue might be a potential prognostic biomarker after tumor resection in HCC patients.PMID:38327651 | PMC:PMC10845065 | DOI:10.2174/0113892029277262231108105441 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Yi-Mei Xiong Fang Zhou Jia-Wen Zhou Fei Liu Si-Qi Zhou Bo Li Zhong-Jian Liu Yang Qin Source Type: research

Identification of Two Novel Pathogenic Variants of the < em > ATM < /em > Gene in the Iranian-Azeri Turkish Ethnic Group by Applying Whole Exome Sequencing
CONCLUSION: Genetic analysis of three unrelated families with ATM-related disorders discovered two novel pathogenic variants. A homozygous missense pathogenic variant was identified in a woman with bi-lateral breast cancer, and a synonymous but pathogenic variant was found in a family with a history of different cancers.PMID:38327652 | PMC:PMC10845066 | DOI:10.2174/0113892029268949231104165301 (Source: Current Genomics)
Source: Current Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Amir-Reza Dalal Amandi Neda Jabbarpour Shadi Shiva Mortaza Bonyadi Source Type: research