Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target
Curr Drug Targets. 2024;25(1):46-61. doi: 10.2174/0113894501279977231210170231.ABSTRACTTranscription factors play a crucial role in providing identity to each cell population. To maintain cell identity, it is essential to balance the expression of activator and inhibitor transcription factors. Cell plasticity and reprogramming offer great potential for future therapeutic applications, as they can regenerate damaged tissue. Specific niche factors can modify gene expression and differentiate or transdifferentiate the target cell to the required fate. Ongoing research is being carried out on the possibilities of transcription...
Source: Current Drug Targets - March 6, 2024 Category: Drugs & Pharmacology Authors: Basheer Abdullah Marzoog Source Type: research

Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target
Curr Drug Targets. 2024;25(1):46-61. doi: 10.2174/0113894501279977231210170231.ABSTRACTTranscription factors play a crucial role in providing identity to each cell population. To maintain cell identity, it is essential to balance the expression of activator and inhibitor transcription factors. Cell plasticity and reprogramming offer great potential for future therapeutic applications, as they can regenerate damaged tissue. Specific niche factors can modify gene expression and differentiate or transdifferentiate the target cell to the required fate. Ongoing research is being carried out on the possibilities of transcription...
Source: Current Drug Targets - March 6, 2024 Category: Drugs & Pharmacology Authors: Basheer Abdullah Marzoog Source Type: research

Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target
Curr Drug Targets. 2024;25(1):46-61. doi: 10.2174/0113894501279977231210170231.ABSTRACTTranscription factors play a crucial role in providing identity to each cell population. To maintain cell identity, it is essential to balance the expression of activator and inhibitor transcription factors. Cell plasticity and reprogramming offer great potential for future therapeutic applications, as they can regenerate damaged tissue. Specific niche factors can modify gene expression and differentiate or transdifferentiate the target cell to the required fate. Ongoing research is being carried out on the possibilities of transcription...
Source: Current Drug Targets - March 6, 2024 Category: Drugs & Pharmacology Authors: Basheer Abdullah Marzoog Source Type: research

Xerostomia: Advances and Challenges in Drug Development
Curr Drug Targets. 2024 Feb 28. doi: 10.2174/0113894501293941240228050343. Online ahead of print.NO ABSTRACTPMID:38424432 | DOI:10.2174/0113894501293941240228050343 (Source: Current Drug Targets)
Source: Current Drug Targets - February 29, 2024 Category: Drugs & Pharmacology Authors: Yoon-Jung Kim Source Type: research

Xerostomia: Advances and Challenges in Drug Development
Curr Drug Targets. 2024 Feb 28. doi: 10.2174/0113894501293941240228050343. Online ahead of print.NO ABSTRACTPMID:38424432 | DOI:10.2174/0113894501293941240228050343 (Source: Current Drug Targets)
Source: Current Drug Targets - February 29, 2024 Category: Drugs & Pharmacology Authors: Yoon-Jung Kim Source Type: research

Xerostomia: Advances and Challenges in Drug Development
Curr Drug Targets. 2024 Feb 28. doi: 10.2174/0113894501293941240228050343. Online ahead of print.NO ABSTRACTPMID:38424432 | DOI:10.2174/0113894501293941240228050343 (Source: Current Drug Targets)
Source: Current Drug Targets - February 29, 2024 Category: Drugs & Pharmacology Authors: Yoon-Jung Kim Source Type: research

Xerostomia: Advances and Challenges in Drug Development
Curr Drug Targets. 2024 Feb 28. doi: 10.2174/0113894501293941240228050343. Online ahead of print.NO ABSTRACTPMID:38424432 | DOI:10.2174/0113894501293941240228050343 (Source: Current Drug Targets)
Source: Current Drug Targets - February 29, 2024 Category: Drugs & Pharmacology Authors: Yoon-Jung Kim Source Type: research

Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System
Curr Drug Targets. 2024 Feb 22. doi: 10.2174/0113894501285598240216065627. Online ahead of print.ABSTRACTCompared to the conventional approach, nanoparticles (NPs) facilitate a non-hazardous, non-toxic, non-interactive, and biocompatible system, rendering them incredibly promising for improving drug delivery to target cells. When that comes to accomplishing specific therapeutic agents like drugs, peptides, nucleotides, etc., lipidic nanoparticulate systems have emerged as even more robust. They have asserted impressive ability in bypassing physiological and cellular barriers, evading lysosomal capture and the proton sponge...
Source: Current Drug Targets - February 27, 2024 Category: Drugs & Pharmacology Authors: Namish Manchanda Harish Vishkarma Muskan Goyal Saurabh Shah Paras Famta Sushama Talegaonkar Saurabh Srivastava Source Type: research

Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System
Curr Drug Targets. 2024 Feb 22. doi: 10.2174/0113894501285598240216065627. Online ahead of print.ABSTRACTCompared to the conventional approach, nanoparticles (NPs) facilitate a non-hazardous, non-toxic, non-interactive, and biocompatible system, rendering them incredibly promising for improving drug delivery to target cells. When that comes to accomplishing specific therapeutic agents like drugs, peptides, nucleotides, etc., lipidic nanoparticulate systems have emerged as even more robust. They have asserted impressive ability in bypassing physiological and cellular barriers, evading lysosomal capture and the proton sponge...
Source: Current Drug Targets - February 27, 2024 Category: Drugs & Pharmacology Authors: Namish Manchanda Harish Vishkarma Muskan Goyal Saurabh Shah Paras Famta Sushama Talegaonkar Saurabh Srivastava Source Type: research

Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System
Curr Drug Targets. 2024 Feb 22. doi: 10.2174/0113894501285598240216065627. Online ahead of print.ABSTRACTCompared to the conventional approach, nanoparticles (NPs) facilitate a non-hazardous, non-toxic, non-interactive, and biocompatible system, rendering them incredibly promising for improving drug delivery to target cells. When that comes to accomplishing specific therapeutic agents like drugs, peptides, nucleotides, etc., lipidic nanoparticulate systems have emerged as even more robust. They have asserted impressive ability in bypassing physiological and cellular barriers, evading lysosomal capture and the proton sponge...
Source: Current Drug Targets - February 27, 2024 Category: Drugs & Pharmacology Authors: Namish Manchanda Harish Vishkarma Muskan Goyal Saurabh Shah Paras Famta Sushama Talegaonkar Saurabh Srivastava Source Type: research

Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
CONCLUSION: We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.PMID:38385490 | DOI:10.2174/0113894501280331240213063333 (Source: Current Drug Targets)
Source: Current Drug Targets - February 22, 2024 Category: Drugs & Pharmacology Authors: Rishabh Chaudhary Janvi Khanna Seema Bansal Nitin Bansal Source Type: research

Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
CONCLUSION: We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.PMID:38385490 | DOI:10.2174/0113894501280331240213063333 (Source: Current Drug Targets)
Source: Current Drug Targets - February 22, 2024 Category: Drugs & Pharmacology Authors: Rishabh Chaudhary Janvi Khanna Seema Bansal Nitin Bansal Source Type: research

Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
CONCLUSION: We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.PMID:38385490 | DOI:10.2174/0113894501280331240213063333 (Source: Current Drug Targets)
Source: Current Drug Targets - February 22, 2024 Category: Drugs & Pharmacology Authors: Rishabh Chaudhary Janvi Khanna Seema Bansal Nitin Bansal Source Type: research

Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
CONCLUSION: We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.PMID:38385490 | DOI:10.2174/0113894501280331240213063333 (Source: Current Drug Targets)
Source: Current Drug Targets - February 22, 2024 Category: Drugs & Pharmacology Authors: Rishabh Chaudhary Janvi Khanna Seema Bansal Nitin Bansal Source Type: research

Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
CONCLUSION: We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.PMID:38385490 | DOI:10.2174/0113894501280331240213063333 (Source: Current Drug Targets)
Source: Current Drug Targets - February 22, 2024 Category: Drugs & Pharmacology Authors: Rishabh Chaudhary Janvi Khanna Seema Bansal Nitin Bansal Source Type: research