Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
Redox interactions in chemo/radiation therapy-induced lung toxicity; mechanisms and therapy perspectives
Curr Drug Targets. 2022 Jul 5. doi: 10.2174/1389450123666220705123315. Online ahead of print.ABSTRACTLung toxicity is a key limiting factor for the therapy of cancer, especially lung, breast, and esophageal malignancies. Radiotherapy for chest and breast malignancies can cause lung injury. However, systemic cancer therapy with chemotherapy also may induce lung pneumonitis and fibrosis. Radiotherapy produces reactive oxygen species (ROS) directly via interacting with water molecules within cells. However, radiation and other therapy modalities may induce the endogenous generation of ROS and nitric oxide (NO) by immune cells...
Source: Current Drug Targets - July 6, 2022 Category: Drugs & Pharmacology Authors: Xixi Lai Masoud Najafi Source Type: research
