Comparative analysis of pharmacokinetics and metabolites of three main terpenoids before and after compatibility of frankincense and myrrh in rats by UHPLC-MS
CONCLUSION: After the compatibility of frankincense and myrrh, the absorption of effective components was improved to some extent, and there were some differences in the metabolites in rats. The results provide ideas for elucidating the in vivo effect mechanism of frankincense and myrrh.PMID:37559536 | DOI:10.2174/1389200224666230808090614 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - August 10, 2023 Category: Drugs & Pharmacology Authors: Ruo-Ying Fan Ru-Meng Gao Jia-Shang Li Shu-Lan Su Er-Xin Shang Da-Wei Qian Jin-Ao Duan Source Type: research
Comparative analysis of pharmacokinetics and metabolites of three main terpenoids before and after compatibility of frankincense and myrrh in rats by UHPLC-MS
CONCLUSION: After the compatibility of frankincense and myrrh, the absorption of effective components was improved to some extent, and there were some differences in the metabolites in rats. The results provide ideas for elucidating the in vivo effect mechanism of frankincense and myrrh.PMID:37559536 | DOI:10.2174/1389200224666230808090614 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - August 10, 2023 Category: Drugs & Pharmacology Authors: Ruo-Ying Fan Ru-Meng Gao Jia-Shang Li Shu-Lan Su Er-Xin Shang Da-Wei Qian Jin-Ao Duan Source Type: research
Comparative analysis of pharmacokinetics and metabolites of three main terpenoids before and after compatibility of frankincense and myrrh in rats by UHPLC-MS
CONCLUSION: After the compatibility of frankincense and myrrh, the absorption of effective components was improved to some extent, and there were some differences in the metabolites in rats. The results provide ideas for elucidating the in vivo effect mechanism of frankincense and myrrh.PMID:37559536 | DOI:10.2174/1389200224666230808090614 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - August 10, 2023 Category: Drugs & Pharmacology Authors: Ruo-Ying Fan Ru-Meng Gao Jia-Shang Li Shu-Lan Su Er-Xin Shang Da-Wei Qian Jin-Ao Duan Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
Covalent modification of proteins by osthole reactive metabolites using proteomic approaches
CONCLUSION: This study provides a novel perspective on the molecular mechanism of OST's pharmacological activities, as well as identifies potential targets for further development and application of OST and other Natural products (NPs).PMID:37519003 | DOI:10.2174/1389200224666230727123006 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Yue Zhuo Huiling Chen Chenchen Liu Yida Zhang Jiansong Fang Meng Li Zhendong Wang Qiyao Jiang Liangwen Yu Huafeng Pan Qi Wang Source Type: research
A mini-review on recent strategies and applications of nanomedicines to combat Antimicrobial Resistance
Curr Drug Metab. 2023 Jul 31. doi: 10.2174/1389200224666230731093319. Online ahead of print.ABSTRACTOne of the key factors contributing to mortality and morbidity globally is infectious ailments. According to recent statistics from WHO, amplified antimicrobial resistance occurrence among bacteria signifies the utmost threat to global public health. Bacteria have developed various strategies to resist antimicrobials, including enzymatic inactivation of antibiotics, drug efflux, modifications of the antibiotic molecule or chemical alteration of the antibiotic, limited drug uptake, etc. Furthermore, the inefficiency of antimi...
Source: Current Drug Metabolism - July 31, 2023 Category: Drugs & Pharmacology Authors: Kanak Chahar Yash Sharma Preeti Patel Vivek Asati Balak Das Kurmi Source Type: research
