Variations in the Design and Use of Attention Control Groups in Type 2 Diabetes Randomized Controlled Trials: a Systematic Review
AbstractPurpose of ReviewIn type 2 diabetes (T2D) research, the phrase “attention control group” (ACGs) has been used with varying descriptions. We aimed to systematically review the variations in the design and use of ACGs for T2D studies.Recent FindingsTwenty studies utilizing ACGs were included in the final evaluation. Control group activities had the potential to influence the primary outcome of the study in 13 of the 20 articles. Prevention of contamination across groups was not mentioned in 45% of the articles. Eighty-five percent of articles met or somewhat met the criteria for having comparable activities betwe...
Source: Current Diabetes Reports - September 1, 2023 Category: Endocrinology Source Type: research
Models Predicting Postpartum Glucose Intolerance Among Women with a History of Gestational Diabetes Mellitus: a Systematic Review
AbstractPurpose of ReviewDespite the crucial role that prediction models play in guiding early risk stratification and timely intervention to prevent type 2 diabetes after gestational diabetes mellitus (GDM), their use is not widespread in clinical practice. The purpose of this review is to examine the methodological characteristics and quality of existing prognostic models predicting postpartum glucose intolerance following GDM.Recent Findings.A systematic review was conducted on relevant risk prediction models, resulting in 15 eligible publications from research groups in various countries. Our review found that traditio...
Source: Current Diabetes Reports - September 1, 2023 Category: Endocrinology Source Type: research
The Effectiveness of Cognitive Behavioral Therapy for Depression Among Individuals with Diabetes: a Systematic Review and Meta-Analysis
AbstractPurpose of ReviewDepression is prevalent and common among individuals living with diabetes. The aim of this review is to systematically assess and meta-analyze the treatment effect of cognitive-behavioral therapy for depression (and other affective outcomes) among patients with diabetes.Recent FindingsEarlier investigations found both psychosocial and pharmacological interventions, including cognitive-behavioral therapy, were promising in managing depression in patients with diabetes, though these findings remain inclusive due to poor study designs and a small number of trials included, which calls for a comprehens...
Source: Current Diabetes Reports - September 1, 2023 Category: Endocrinology Source Type: research
Sexual Function and Satisfaction in the Context of Obesity
AbstractPurpose of ReviewSexual dysfunction is commonly associated with overweight/obesity, but the underlying physiological and psychosocial mechanisms are not fully understood. This review contextualizes the obesity-sexual (dys)function relationship, describes recent insights from the medical and social science literature, and suggests opportunities for continued research.Recent FindingsAlthough sexual dysfunction has been historically evaluated as a consequence/outcome of obesity, it is increasingly considered as a harbinger of future metabolic comorbidities, including type 2 diabetes and cardiovascular disease. Body im...
Source: Current Diabetes Reports - August 26, 2023 Category: Endocrinology Source Type: research
The T1D Index: Implications of Initial Results, Data Limitations, and Future Development
AbstractPurpose of the ReviewCurrent global information on incidence, prevalence, and mortality of type 1 diabetes (T1D) is limited, particularly in low- and middle-income countries. To address this gap in evidence, JDRF, Life for a Child, International Society for Pediatric and Adolescent Diabetes, and International Diabetes Federation have developed the T1D Index, which uses a Markov mathematical model, and machine learning and all available data to provide global estimates of the burden on T1D. This review assesses the methodology, limitations, current findings, and future directions of the Index.Recent FindingsGlobal p...
Source: Current Diabetes Reports - August 23, 2023 Category: Endocrinology Source Type: research
Sarcopenic Obesity and Cardiometabolic Health and Mortality in Older Adults: a Growing Health Concern in an Ageing Population
AbstractPurpose of ReviewSarcopenic obesity (SO) is a growing public health problem in older adults. Whether SO confers higher risk of cardiometabolic disease and mortality than obesity or sarcopenia alone is still a matter of debate. We focus on recent findings on SO and cardiometabolic health and mortality in older adults.Recent FindingsSO is associated with increased mortality compared to non-sarcopenic obesity, but similar mortality risk compared to sarcopenia without obesity. SO is associated with a higher risk of cardiovascular disease (CVD), diabetes, and physical disability than obesity or sarcopenia alone. SO, in ...
Source: Current Diabetes Reports - August 11, 2023 Category: Endocrinology Source Type: research
Team-Based Approach to Reduce Malignancies in People with Diabetes and Obesity
AbstractPurpose of ReviewNumerous observations have indicated an increased risk of developing various types of cancers, as well as cancer-related mortality, among patients with diabetes and obesity. The purpose of this review is to outline multiple-cancer screening among these patients through a team-based approach and to present the findings of a pioneering integrated care program designed for patients with obesity with a specific emphasis on cancer prevention.Recent FindingsA community-based multi-cancer prevention program, which provides all services in one location and utilizes team-based approaches, is reported to be ...
Source: Current Diabetes Reports - August 3, 2023 Category: Endocrinology Source Type: research
Challenges and Opportunities in Diagnosis and Management of Cardiometabolic Risk in Adolescents
AbstractPurpose of ReviewThis review aims to elucidate the limitations of diagnosing metabolic syndrome in adolescents as well as challenges and opportunities in the identification and reduction of cardiometabolic risk in this population.Recent FindingsThere are multiple criticisms of how we define and approach obesity in clinical practice and scientific research, and weight stigma further complicates the process of making and communicating weight-related diagnoses. While the goal of diagnosing and managing metabolic syndrome in adolescents would be to identify individuals at elevated future cardiometabolic risk and interv...
Source: Current Diabetes Reports - August 1, 2023 Category: Endocrinology Source Type: research
Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence
AbstractPurpose of ReviewMultiple studies report an increased incidence of diabetes following SARS-CoV-2 infection. Given the potential increased global burden of diabetes, understanding the effect of SARS-CoV-2 in the epidemiology of diabetes is important. Our aim was to review the evidence pertaining to the risk of incident diabetes after COVID-19 infection.Recent FindingsIncident diabetes risk increased by approximately 60% compared to patients without SARS-CoV-2 infection. Risk also increased compared to non-COVID-19 respiratory infections, suggesting SARS-CoV-2-mediated mechanisms rather than general morbidity after r...
Source: Current Diabetes Reports - August 1, 2023 Category: Endocrinology Source Type: research
The Effectiveness of Cognitive Behavioral Therapy for Depression Among Individuals with Diabetes: a Systematic Review and Meta-Analysis
AbstractPurpose of ReviewDepression is prevalent and common among individuals living with diabetes. The aim of this review is to systematically assess and meta-analyze the treatment effect of cognitive-behavioral therapy for depression (and other affective outcomes) among patients with diabetes.Recent FindingsEarlier investigations found both psychosocial and pharmacological interventions, including cognitive-behavioral therapy, were promising in managing depression in patients with diabetes, though these findings remain inclusive due to poor study designs and a small number of trials included, which calls for a comprehens...
Source: Current Diabetes Reports - June 17, 2023 Category: Endocrinology Source Type: research
Variations in the Design and Use of Attention Control Groups in Type 2 Diabetes Randomized Controlled Trials: a Systematic Review
AbstractPurpose of ReviewIn type 2 diabetes (T2D) research, the phrase “attention control group” (ACGs) has been used with varying descriptions. We aimed to systematically review the variations in the design and use of ACGs for T2D studies.Recent FindingsTwenty studies utilizing ACGs were included in the final evaluation. Control group activities had the potential to influence the primary outcome of the study in 13 of the 20 articles. Prevention of contamination across groups was not mentioned in 45% of the articles. Eighty-five percent of articles met or somewhat met the criteria for having comparable activities betwe...
Source: Current Diabetes Reports - June 9, 2023 Category: Endocrinology Source Type: research
