Exploring the Mechanistic Link Between Obesity and Heart Failure
AbstractPurpose of ReviewAmong subtypes of cardiovascular disease, obesity has a potent and unique association with heart failure (HF) that is unexplained by traditional cardiovascular risk mediators. The concomitant rise in the prevalence of obesity and HF necessitates better understanding of their relationship to develop effective prevention and treatment strategies. The purpose of this review is to provide mechanistic insight regarding the link between obesity and HF by elucidating the direct and indirect pathways linking the two conditions.Recent FindingsSeveral direct pathophysiologic mechanisms contribute to HF risk ...
Source: Current Diabetes Reports - December 15, 2023 Category: Endocrinology Source Type: research
Imeglimin: the New Kid on the Block
AbstractPurpose of ReviewThis review aims to collect all the data regarding imeglimin and present it as one of the options for managing diabetes.Recent FindingsIt is a new drug that has recently been approved as an oral anti-diabetic drug, either as monotherapy or in combination with other oral antidiabetic drugs including insulin, with modest HbA1c reduction, and a fairly safe profile. Imeglimin was first approved in 2021 in Japan and China and is available in India from October 2022.SummaryImeglimin is the first compound in a new class of oral anti-diabetic medications known as “glimins” that include a tetrahydrotria...
Source: Current Diabetes Reports - December 5, 2023 Category: Endocrinology Source Type: research
Exploring the Mechanistic Link Between Obesity and Heart Failure
AbstractPurpose of ReviewAmong subtypes of cardiovascular disease, obesity has a potent and unique association with heart failure (HF) that is unexplained by traditional cardiovascular risk mediators. The concomitant rise in the prevalence of obesity and HF necessitates better understanding of their relationship to develop effective prevention and treatment strategies. The purpose of this review is to provide mechanistic insight regarding the link between obesity and HF by elucidating the direct and indirect pathways linking the two conditions.Recent FindingsSeveral direct pathophysiologic mechanisms contribute to HF risk ...
Source: Current Diabetes Reports - December 1, 2023 Category: Endocrinology Source Type: research
Obesity and Severity of Menopausal Symptoms: a Contemporary Review
AbstractPurpose of ReviewVasomotor symptoms are frequently experienced by women during menopause and have been linked to obesity. Severity of menopausal symptoms is a distinct construct from presence of symptoms, and the relation between severity of symptoms and obesity is less established. The purpose of this brief narrative review was to summarize evidence from recent studies on associations between menopausal symptom severity and measures of obesity.Recent FindingsSixteen articles were identified that specifically assessed and reported on the severity of menopausal symptoms in relation to measures of obesity including b...
Source: Current Diabetes Reports - December 1, 2023 Category: Endocrinology Source Type: research
Impact of the Neighborhood Food Environment on Dietary Intake and Obesity: a Review of the Recent Literature
AbstractPurpose of ReviewThe built environment impacts obesogenic behaviors and in turn body weight outcomes. This review summarizes recent research demonstrating environmental impacts on dietary intake and obesity with a specific focus on the neighborhood food environment.Recent FindingsIn the previous five years, an abundance of reviews and research studies have been undertaken to elucidate how the neighborhood food environment impacts diet and obesity. This includes studies using primary data collection and secondary data analyses in various populations across the globe. Taken together, current research presents mixed e...
Source: Current Diabetes Reports - December 1, 2023 Category: Endocrinology Source Type: research
Obesity and Severity of Menopausal Symptoms: a Contemporary Review
AbstractPurpose of ReviewVasomotor symptoms are frequently experienced by women during menopause and have been linked to obesity. Severity of menopausal symptoms is a distinct construct from presence of symptoms, and the relation between severity of symptoms and obesity is less established. The purpose of this brief narrative review was to summarize evidence from recent studies on associations between menopausal symptom severity and measures of obesity.Recent FindingsSixteen articles were identified that specifically assessed and reported on the severity of menopausal symptoms in relation to measures of obesity including b...
Source: Current Diabetes Reports - November 24, 2023 Category: Endocrinology Source Type: research
Positive Psychology Interventions for Improving Self-management Behaviors in Patients with Type 1 and Type 2 Diabetes: a Narrative Review of Current Evidence
AbstractPurpose of ReviewInterests have been emerging in using positive psychology interventions (PPIs) to improve diabetes self-management (DSM) behaviors (e.g., blood glucose monitoring, physical activity). To explore the impact of those interventions on DSM behaviors, we summarized the evidence of PPIs on self-management behaviors among both type 1 diabetes (T1D) and type 2 diabetes (T2D) patients between 2012 and 2022.Recent FindingsAmong the eight studies identified, different study designs and types of PPIs were apparent. Typical PPIs (e.g., activities enhancing positive affect/gratitude/self-affirmation/optimism) we...
Source: Current Diabetes Reports - November 1, 2023 Category: Endocrinology Source Type: research
Workplace Interventions for Type 2 Diabetes Mellitus Prevention —an Umbrella Review
AbstractPurpose of reviewType 2 diabetes mellitus (T2DM) is a chronic disease that may lead to severe complications. The main methods of preventing or delaying the onset of T2DM include lifestyle changes. The purpose of this study is to identify and evaluate the effectiveness of workplace interventions aimed at preventing type 2 diabetes. An umbrella review was conducted in accordance with the Cochrane Collaboration guidelines. Searches were performed in Medline (via PubMed), Embase (via OVID), and Cochrane Library databases. The quality assessment of the included studies was performed using the AMSTAR2 tool.Recent findi...
Source: Current Diabetes Reports - September 20, 2023 Category: Endocrinology Source Type: research
Correction to: The T1D Index: Implications of Initial Results, Data Limitations, and Future Development
(Source: Current Diabetes Reports)
Source: Current Diabetes Reports - September 14, 2023 Category: Endocrinology Source Type: research
How Could Taxes on Sugary Drinks and Foods Help Reduce the Burden Of Type 2 Diabetes?
AbstractPurpose of ReviewTaxes on sugary drinks and foods have emerged as a key strategy to counteract the alarming levels of diabetes worldwide. Added sugar consumption from industrialized foods and beverages has been strongly linked to type 2 diabetes. This review provides a synthesis of evidence on how taxes on sugary products can influence the onset of type 2 diabetes, describing the importance of the different mechanisms through which the consumption of these products is reduced, leading to changes in weight and potentially a decrease in the incidence of type 2 diabetes.Recent FindingsObservational studies have shown ...
Source: Current Diabetes Reports - September 11, 2023 Category: Endocrinology Source Type: research
