The Interplay of Comorbidities in Chronic Heart Failure: Challenges and Solutions
CONCLUSION: There is a pressing need for a multidisciplinary, tailored approach to manage HF and its intricate comorbidities. This review underscores the importance of ongoing research efforts to devise targeted treatment strategies for HF patients with various comorbid conditions.PMID:38347774 | DOI:10.2174/011573403X289572240206112303 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - February 13, 2024 Category: Cardiology Authors: Shashipriya Agress Jannat S Sheikh Aida A Perez Ramos Durlav Kashyap Soha Razmjouei Joy Kumar Mankaranvir Singh Muhammad Ali Lak Ali Osman Muhammad Zia Ul Haq Source Type: research
Breathomics Detect the Cardiovascular Disease: Delusion or Dilution of the Metabolomic Signature
Curr Cardiol Rev. 2024 Feb 2. doi: 10.2174/011573403X283768240124065853. Online ahead of print.ABSTRACTVolatile organic compounds (VOCs) can be subdivided into exogenous and endogenous categories based on their origin. Analyzing the endogenous VOCs can provide insights into maintaining the internal organs' homeostasis. Despite the ongoing development and the current understanding, studies have suggested a link between cardiovascular metabolic alterations in patients with ischemic heart disease and elevated levels of ethane and isoprene detectable through exhaled breath analysis. Conversely, patients with chronic heart fail...
Source: Current Cardiology Reviews - February 6, 2024 Category: Cardiology Authors: Basheer Abdullah Marzoog Source Type: research
Emerging Strategies and Effective Prevention Measures for Investigating the Association Between Stroke and Sudden Cardiac Fatality
Curr Cardiol Rev. 2024 Jan 19. doi: 10.2174/011573403X259676231222053709. Online ahead of print.ABSTRACTStroke-related cardiac death is a significant concern for patients with stroke and their healthcare providers. It is a complex and multifaceted condition that requires careful management of both modifiable and non-modifiable risk factors. This review provides an overview of the pathophysiology, risk factors, and prevention strategies for stroke-related cardiac death. The review highlights the importance of identifying and managing modifiable risk factors such as hypertension, diabetes, and lifestyle factors, as well as n...
Source: Current Cardiology Reviews - February 4, 2024 Category: Cardiology Authors: H Nithesh Kumar S Jeevanandham Shankar Ganesh M M Ashmi Sabana P Manivasakam Source Type: research
Dietary Effects of Fasting on the Lipid Panel
CONCLUSION: This review evaluates the current literature regarding the effects of this dietary model and other types of fasting on the lipid panel.PMID:38310558 | DOI:10.2174/011573403X257173231222042846 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - February 4, 2024 Category: Cardiology Authors: Jason Hourizadeh Rezwan Munshi Roman Zeltser Amgad Makaryus Source Type: research
The Role of Triglycerides in Atherosclerosis: Recent Pathophysiologic Insights and Therapeutic Implications
In conclusion, this review underscores the importance of a nuanced approach to understanding the role of triglycerides in atherosclerosis and their potential as a therapeutic target. Further research is needed to unravel the complex interplay between triglycerides, triglyceride-rich lipoproteins, and associated factors in atherosclerosis pathogenesis and refine triglyceride-targeted therapeutic strategies.PMID:38288833 | DOI:10.2174/011573403X272750240109052319 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - January 30, 2024 Category: Cardiology Authors: Yonatan Akivis Hussam Alkaissi Samy I McFarlane Inna Bukharovich Source Type: research
Pharmacological Treatment of Heart Failure: Recent Advances
CONCLUSION: The current quadruple therapy in the treatment of heart failure has demonstrated a reduction in the hospitalization of patients and a decrease in mortality associated with the condition. Individualized heart failure therapy research have shown some benefit in select heart failure patients. Further research on novel therapies will help improve heart failure patient outcomes.PMID:38284706 | DOI:10.2174/011573403X270178231228061314 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - January 29, 2024 Category: Cardiology Authors: Jonathan C H Chan Areeb Siddiqui Source Type: research
Arrhythmias and Hypertrophic Cardiomyopathy: Unravelling the Connection
This article aims to discuss the pathophysiology of arrhythmia in HCM and clinical recommendations for various ventricular and atrial fibrillation including catheter ablation and implantable cardioverter-defibrillator (ICD).PMID:38279754 | DOI:10.2174/011573403X279223231227111737 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - January 27, 2024 Category: Cardiology Authors: Kanishk Aggarwal Sri Pranvi Boyapati Jayesh Valecha Amna Noor Fnu Kanwal Rohit Jain Sai Gautham Kanagala Source Type: research
Cardiac Axis in Early Gestation and Congenital Heart Disease
Curr Cardiol Rev. 2024 Jan 24. doi: 10.2174/011573403X264660231210162041. Online ahead of print.ABSTRACTCongenital heart defects represent the most common structural anomalies observed in the fetal population, and they are often associated with significant morbidity and mortality. The fetal cardiac axis, which indicates the orientation of the heart in relation to the chest wall, is formed by the angle between the anteroposterior axis of the chest and the interventricular septum of the heart. Studies conducted during the first trimester have demonstrated promising outcomes with respect to the applicability of cardiac axis m...
Source: Current Cardiology Reviews - January 27, 2024 Category: Cardiology Authors: D Carrasco L Guedes-Martins Source Type: research
Cardiovascular Symptoms, Dysautonomia, and Quality of Life in Adult and Pediatric Patients with Hypermobile Ehlers-Danlos Syndrome: A Brief Review
CONCLUSION: While studies have examined cardiovascular symptoms and the impact of dysautonomia in adults with and without hEDS, there is scant literature on dysautonomia in pediatric patients with hEDS. Therefore, more studies on cardiovascular symptoms and dysautonomia, as they relate to the quality of life in pediatric patients with hEDS, are needed. This brief review summarizes the current literature on dysautonomia and cardiovascular symptoms in pediatric and adult populations with hEDS.PMID:38275067 | DOI:10.2174/011573403X271096231203164216 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - January 26, 2024 Category: Cardiology Authors: Amanda Hertel William R Black Lindsey Malloy Walton Julie Martin Jordan Jones Source Type: research
Nuchal Translucency and Congenital Heart Defects
Curr Cardiol Rev. 2024 Jan 24. doi: 10.2174/011573403X264963231128045500. Online ahead of print.ABSTRACTNuchal translucency comprises a temporary accumulation of fluid in the subcutaneous tissue on the back of a fetus's neck, which accompanies the crown-rump length and is observed through an ultrasound performed between 11 and 13 weeks + 6 days gestation. Nuchal translucency is considered to be above normal when values are higher than the 95th/99th percentile or equal to or higher than 2.5/3.5 mm. The first connection between increased nuchal translucency and the presence of congenital heart defects is described in the stu...
Source: Current Cardiology Reviews - January 26, 2024 Category: Cardiology Authors: A Sofia-Gon çalves L Guedes-Martins Source Type: research
Novel Strategies to Improve the Cardioprotective Effects of Cardioplegia
Curr Cardiol Rev. 2024 Jan 24. doi: 10.2174/011573403X263956231129064455. Online ahead of print.ABSTRACTThe use of cardioprotective strategies as adjuvants of cardioplegic solutions has become an ideal alternative for the improvement of post-surgery heart recovery. The choice of the optimal cardioplegia, as well as its distribution mechanism, remains controversial in the field of cardiovascular surgery. There is still a need to search for new and better cardioprotective methods during cardioplegic procedures. New techniques for the management of cardiovascular complications during cardioplegia have evolved with new alterna...
Source: Current Cardiology Reviews - January 26, 2024 Category: Cardiology Authors: Estefanie Osorio-Llanes Jairo Castellar-L ópez Wendy Rosales-Rada Yulieth Montoya John Bustamante Ricardo Zalaquett Roberto Bravo-Sagua Jaime A Riquelme Gina S ánchez Mario Chiong Sergio Lavandero Evelyn Mendoza-Torres Source Type: research
The Impact of Polypill on Adherence and Cardiovascular Outcomes: A Comprehensive Systematic Review with Meta-Analysis
CONCLUSION: Polypills were found to significantly reduce SBP, DBP and MACE. An improvement in medication adherence was also observed among polypill users, which might be responsible for the significant reduction in SBP observed users. Future research might benefit from exploring a more personalized approach to the composition of polypills, which could reveal a more clinically significant impact of increased adherence on CVD outcomes.PMID:38265377 | DOI:10.2174/011573403X283174240110025442 (Source: Current Cardiology Reviews)
Source: Current Cardiology Reviews - January 24, 2024 Category: Cardiology Authors: Hamza Salim Basel Musmar Motaz Saifi Mohammed Ayyad Mohammed Ruzieh Jehad Azar Zaher Nazzal Source Type: research
Physiological Evidence and Therapeutic Outcomes of Vitamin D on Cardiovascular Diseases
Curr Cardiol Rev. 2024 Jan 18. doi: 10.2174/011573403X263417231107110618. Online ahead of print.ABSTRACTVitamin D hormone is an important regulator of various physiological functions, and its deficiency is characterized by an imbalance in parathyroid hormone and calcium homeostasis. The role of vitamin D in cardiovascular physiology is well demonstrated in animal and humanbased studies. In this context, hyperlipidemia, increased atherogenic plaques, cardiac inflammation, hypertension, myocarditis, myocardial infarction, and heart failure are some of the commonest known conditions connected with vitamin D deficiency. Supple...
Source: Current Cardiology Reviews - January 20, 2024 Category: Cardiology Authors: Abolfazl Zendehdel Amir Shakarami Ehsan Sekhavati Moghadam Source Type: research
Genetic Determinants of Response to Statins in Cardiovascular Diseases
Curr Cardiol Rev. 2024 Jan 9. doi: 10.2174/011573403X267793231220114042. Online ahead of print.ABSTRACTDespite extensive efforts to identify patients with cardiovascular disease (CVD) who could most benefit from the treatment approach, patients vary in their benefit from therapy and propensity for adverse drug events. Genetic variability in individual responses to drugs (pharmacogenetics) is considered an essential determinant in responding to a drug. Thus, understanding these pharmacogenomic relationships has led to a substantial focus on mechanisms of disease and drug response. In turn, understanding the genomic and mole...
Source: Current Cardiology Reviews - January 11, 2024 Category: Cardiology Authors: Ghazaleh Ghorbannezhad Shima Mehrabadi Negar Golampour-Shamkani Amirhossein Barjasteh Poorya Etesamizadeh Mohammad Tayyebi Majid Khazaei Seyed Mahdi Hassanian Gordon A Ferns Amir Avan Source Type: research
Understanding the Role of Galectin-1 in Heart Failure: A Comprehensive Narrative Review
Curr Cardiol Rev. 2024 Jan 8. doi: 10.2174/011573403X274886231227111902. Online ahead of print.ABSTRACTHeart failure (HF) is the fastest-growing cardiovascular condition worldwide. The immune system may play a role in the development of HF since this condition is associated with elevated pro-inflammatory cytokine levels. HF is a life-threatening disease, and there is an increasing demand for diagnostic biomarkers, prognostic factors, and therapeutic agents that can help treat it. Galectin-1 (Gal-1) is the prototype galectin of the lectin family. Multiple signal transduction pathways are regulated by Ras proteins, which act...
Source: Current Cardiology Reviews - January 9, 2024 Category: Cardiology Authors: Mohammad Javad Sotoudeheian Seyed-Mohamad-Sadegh Mirahmadi Mohammad Pirhayati Reza Azarbad Soroush Nematollahi Mehdi Taghizadeh Hamidreza Pazoki-Toroudi Source Type: research
