Cortical cellular encoding of thermotactile integration
Curr Biol. 2024 Apr 1:S0960-9822(24)00315-4. doi: 10.1016/j.cub.2024.03.018. Online ahead of print.ABSTRACTRecent evidence suggests that primary sensory cortical regions play a role in the integration of information from multiple sensory modalities. How primary cortical neurons integrate different sources of sensory information is unclear, partly because non-primary sensory input to a cortical sensory region is often weak or modulatory. To address this question, we take advantage of the robust representation of thermal (cooling) and tactile stimuli in mouse forelimb primary somatosensory cortex (fS1). Using a thermotactile...
Source: Current Biology - April 6, 2024 Category: Biology Authors: Philipp Schnepel Ricardo Paricio-Montesinos Ivan Ezquerra-Romano Patrick Haggard James F A Poulet Source Type: research
Cortical cellular encoding of thermotactile integration
Curr Biol. 2024 Apr 1:S0960-9822(24)00315-4. doi: 10.1016/j.cub.2024.03.018. Online ahead of print.ABSTRACTRecent evidence suggests that primary sensory cortical regions play a role in the integration of information from multiple sensory modalities. How primary cortical neurons integrate different sources of sensory information is unclear, partly because non-primary sensory input to a cortical sensory region is often weak or modulatory. To address this question, we take advantage of the robust representation of thermal (cooling) and tactile stimuli in mouse forelimb primary somatosensory cortex (fS1). Using a thermotactile...
Source: Current Biology - April 6, 2024 Category: Biology Authors: Philipp Schnepel Ricardo Paricio-Montesinos Ivan Ezquerra-Romano Patrick Haggard James F A Poulet Source Type: research
Cortical cellular encoding of thermotactile integration
Curr Biol. 2024 Apr 1:S0960-9822(24)00315-4. doi: 10.1016/j.cub.2024.03.018. Online ahead of print.ABSTRACTRecent evidence suggests that primary sensory cortical regions play a role in the integration of information from multiple sensory modalities. How primary cortical neurons integrate different sources of sensory information is unclear, partly because non-primary sensory input to a cortical sensory region is often weak or modulatory. To address this question, we take advantage of the robust representation of thermal (cooling) and tactile stimuli in mouse forelimb primary somatosensory cortex (fS1). Using a thermotactile...
Source: Current Biology - April 6, 2024 Category: Biology Authors: Philipp Schnepel Ricardo Paricio-Montesinos Ivan Ezquerra-Romano Patrick Haggard James F A Poulet Source Type: research
Daphnia uses its circadian clock for short-day recognition in environmental sex determination
Curr Biol. 2024 Mar 27:S0960-9822(24)00324-5. doi: 10.1016/j.cub.2024.03.027. Online ahead of print.ABSTRACTSome organisms have developed a mechanism called environmental sex determination (ESD), which allows environmental cues, rather than sex chromosomes or genes, to determine offspring sex.1,2,3,4 ESD is advantageous to optimize sex ratios according to environmental conditions, enhancing reproductive success.5,6 However, the process by which organisms perceive and translate diverse environmental signals into offspring sex remains unclear. Here, we analyzed the environmental perception mechanism in the crustacean, Daphni...
Source: Current Biology - April 5, 2024 Category: Biology Authors: Shione Abe Yugo Takahata Hitoshi Miyakawa Source Type: research
Daphnia uses its circadian clock for short-day recognition in environmental sex determination
Curr Biol. 2024 Mar 27:S0960-9822(24)00324-5. doi: 10.1016/j.cub.2024.03.027. Online ahead of print.ABSTRACTSome organisms have developed a mechanism called environmental sex determination (ESD), which allows environmental cues, rather than sex chromosomes or genes, to determine offspring sex.1,2,3,4 ESD is advantageous to optimize sex ratios according to environmental conditions, enhancing reproductive success.5,6 However, the process by which organisms perceive and translate diverse environmental signals into offspring sex remains unclear. Here, we analyzed the environmental perception mechanism in the crustacean, Daphni...
Source: Current Biology - April 5, 2024 Category: Biology Authors: Shione Abe Yugo Takahata Hitoshi Miyakawa Source Type: research
A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
Curr Biol. 2024 Mar 27:S0960-9822(24)00312-9. doi: 10.1016/j.cub.2024.03.015. Online ahead of print.ABSTRACTPlants establish symbiotic associations with arbuscular mycorrhizal fungi (AMF) to facilitate nutrient uptake, particularly in nutrient-limited conditions. This partnership is rooted in the plant's ability to recognize fungal signaling molecules, such as chitooligosaccharides (chitin) and lipo-chitooligosaccharides. In the legume Medicago truncatula, chitooligosaccharides trigger both symbiotic and immune responses via the same lysin-motif-receptor-like kinases (LysM-RLKs), notably CERK1 and LYR4. The nature of plant...
Source: Current Biology - April 4, 2024 Category: Biology Authors: Jingyi Zhang Jongho Sun Chai Hao Chiu David Landry Kangping Li Jiangqi Wen Kirankumar S Mysore S ébastien Fort Benoit Lefebvre Giles E D Oldroyd Feng Feng Source Type: research
Effects of neural oscillation power and phase on discrimination performance in a visual tilt illusion
We presented center gratings at participants' subjective vertical angle and had participants report whether the grating appeared tilted clockwise or counterclockwise from vertical on each trial while measuring their brain activity with electroencephalography (EEG). In addition to effects of alpha power and aperiodic slope, we observed robust associations between orientation perception and alpha and theta phase, consistent with fluctuating illusion magnitude across the oscillatory cycle. These results confirm that oscillation phase affects the complex processing involved in stimulus discrimination, consistent with its purpo...
Source: Current Biology - April 3, 2024 Category: Biology Authors: Jessica G Williams William J Harrison Henry A Beale Jason B Mattingley Anthony M Harris Source Type: research
Effects of neural oscillation power and phase on discrimination performance in a visual tilt illusion
We presented center gratings at participants' subjective vertical angle and had participants report whether the grating appeared tilted clockwise or counterclockwise from vertical on each trial while measuring their brain activity with electroencephalography (EEG). In addition to effects of alpha power and aperiodic slope, we observed robust associations between orientation perception and alpha and theta phase, consistent with fluctuating illusion magnitude across the oscillatory cycle. These results confirm that oscillation phase affects the complex processing involved in stimulus discrimination, consistent with its purpo...
Source: Current Biology - April 3, 2024 Category: Biology Authors: Jessica G Williams William J Harrison Henry A Beale Jason B Mattingley Anthony M Harris Source Type: research
A chronometric study of the posterior cerebellum's function in emotional processing
Curr Biol. 2024 Mar 27:S0960-9822(24)00310-5. doi: 10.1016/j.cub.2024.03.013. Online ahead of print.ABSTRACTThe posterior cerebellum is a recently discovered hub of the affective and social brain, with different subsectors contributing to different social functions. However, very little is known about when the posterior cerebellum plays a critical role in social processing. Due to its location and anatomy, it has been difficult to use traditional approaches to directly study the chronometry of the cerebellum. To address this gap in cerebellar knowledge, here we investigated the causal contribution of the posterior cerebell...
Source: Current Biology - April 2, 2024 Category: Biology Authors: Andrea Ciricugno Chiara Ferrari Lorella Battelli Zaira Cattaneo Source Type: research
A chronometric study of the posterior cerebellum's function in emotional processing
Curr Biol. 2024 Mar 27:S0960-9822(24)00310-5. doi: 10.1016/j.cub.2024.03.013. Online ahead of print.ABSTRACTThe posterior cerebellum is a recently discovered hub of the affective and social brain, with different subsectors contributing to different social functions. However, very little is known about when the posterior cerebellum plays a critical role in social processing. Due to its location and anatomy, it has been difficult to use traditional approaches to directly study the chronometry of the cerebellum. To address this gap in cerebellar knowledge, here we investigated the causal contribution of the posterior cerebell...
Source: Current Biology - April 2, 2024 Category: Biology Authors: Andrea Ciricugno Chiara Ferrari Lorella Battelli Zaira Cattaneo Source Type: research
Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery
Curr Biol. 2024 Mar 25:S0960-9822(24)00307-5. doi: 10.1016/j.cub.2024.03.010. Online ahead of print.ABSTRACTNeurons rely on the long-range trafficking of synaptic components to form and maintain the complex neural networks that encode the human experience. With a single neuron capable of forming thousands of distinct en passant synapses along its axon, spatially precise delivery of the necessary synaptic components is paramount. How these synapses are patterned, as well as how the efficient delivery of synaptic components is regulated, remains largely unknown. Here, we reveal a novel role for the microtubule (MT)-severing ...
Source: Current Biology - March 30, 2024 Category: Biology Authors: Jayne Aiken Erika L F Holzbaur Source Type: research
Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery
Curr Biol. 2024 Mar 25:S0960-9822(24)00307-5. doi: 10.1016/j.cub.2024.03.010. Online ahead of print.ABSTRACTNeurons rely on the long-range trafficking of synaptic components to form and maintain the complex neural networks that encode the human experience. With a single neuron capable of forming thousands of distinct en passant synapses along its axon, spatially precise delivery of the necessary synaptic components is paramount. How these synapses are patterned, as well as how the efficient delivery of synaptic components is regulated, remains largely unknown. Here, we reveal a novel role for the microtubule (MT)-severing ...
Source: Current Biology - March 30, 2024 Category: Biology Authors: Jayne Aiken Erika L F Holzbaur Source Type: research
Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery
Curr Biol. 2024 Mar 25:S0960-9822(24)00307-5. doi: 10.1016/j.cub.2024.03.010. Online ahead of print.ABSTRACTNeurons rely on the long-range trafficking of synaptic components to form and maintain the complex neural networks that encode the human experience. With a single neuron capable of forming thousands of distinct en passant synapses along its axon, spatially precise delivery of the necessary synaptic components is paramount. How these synapses are patterned, as well as how the efficient delivery of synaptic components is regulated, remains largely unknown. Here, we reveal a novel role for the microtubule (MT)-severing ...
Source: Current Biology - March 30, 2024 Category: Biology Authors: Jayne Aiken Erika L F Holzbaur Source Type: research
Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer's Disease
Curr Biol. 2024 Mar 28:S0960-9822(24)00380-4. doi: 10.1016/j.cub.2024.03.040. Online ahead of print.NO ABSTRACTPMID:38552626 | DOI:10.1016/j.cub.2024.03.040 (Source: Current Biology)
Source: Current Biology - March 29, 2024 Category: Biology Authors: Sarah D Cushing Ivan Skelin Shawn C Moseley Alina C Stimmell Jessica R Dixon Andreza S Melilli Leonardo Molina Bruce L McNaughton Aaron A Wilber Source Type: research
The oldest mysticete in the Northern Hemisphere
Curr Biol. 2024 Mar 19:S0960-9822(24)00308-7. doi: 10.1016/j.cub.2024.03.011. Online ahead of print.ABSTRACTExtant baleen whales (Mysticeti) uniquely use keratinous baleen for filter-feeding and lack dentition, but the fossil record clearly shows that "toothed" baleen whales first appeared in the Late Eocene.1 Globally, only two Eocene mysticetes have been found, and both are from the Southern Hemisphere: Mystacodon selenensis from Peru, 36.4 mega-annum (Ma) ago1,2 and Llanocetus denticrenatus from Antarctica, 34.2 Ma ago.3,4 Based on a partial skull from the lower part of the Lincoln Creek Formation in Washington State, U...
Source: Current Biology - March 29, 2024 Category: Biology Authors: Cheng-Hsiu Tsai James L Goedert Robert W Boessenecker Source Type: research
