Mechanisms and risk factors of thrombosis in cancer
The close relationship between cancer and thrombosis is known since more than a century. Venous thromboembolism (VTE) may be the first manifestation of an occult malignancy in an otherwise healthy individual. Cancer patients commonly present with abnormalities of laboratory coagulation tests, indicating an ongoing subclinical hypercoagulable condition. The results of laboratory tests demonstrate that a process of fibrin formation and removal parallels the development of malignancy, which is of particular interest since fibrin and other clotting products are important for both thrombogenesis and tumor progression. (Source: ...
Source: Critical Reviews in Oncology Hematology - August 25, 2017 Category: Cancer & Oncology Authors: Anna Falanga, Laura Russo, Viola Milesi, Alfonso Vignoli Source Type: research

Cancer-related Fatigue in Adolescents and Young Adults: A Systematic Review of the Literature
Adolescents and young adults with cancer (AYA) represent a specific age cohort dealing with the disease in a stage of life characterized by development, upheavals, and establishment. The aim of this study was to point out the state of research on how AYA are affected by cancer-related fatigue (CRF). (Source: Critical Reviews in Oncology Hematology)
Source: Critical Reviews in Oncology Hematology - August 24, 2017 Category: Cancer & Oncology Authors: E. Nowe, Y. St öbel-Richter, A. Sender, K. Leuteritz, M. Friedrich, K. Geue Tags: Review article Source Type: research

Urinary biomarkers in prostate cancer detection and monitoring progression
Prostate cancer (CaP) is the most common cancer in men and the second leading cause of cancer deaths in males in Australia. Although serum prostate-specific antigen (PSA) has been the most widely used biomarker in CaP detection for decades, PSA screening has limitations such as low specificity and potential association with over-diagnosis. Current biomarkers used in the clinic are not useful for the early detection of CaP, or monitoring its progression, and have limited value in predicting response to treatment. (Source: Critical Reviews in Oncology Hematology)
Source: Critical Reviews in Oncology Hematology - August 19, 2017 Category: Cancer & Oncology Authors: Duojia Wu, Jie Ni, Julia Beretov, Paul Cozzi, Mark Willcox, Valerie Wasinger, Bradley Walsh, Peter Graham, Yong Li Source Type: research

Cognitive impairment and chemotherapy: A brief overview
In the last years chemotherapy has significantly increased overall survival in patients with different cancer types. However, chemotherapy drugs often cause various side effects and many patients report a decline in cognitive function. These disordersaffect several cognitive domains over time: memory, speed of cognitive processes and executive functions are especially involved (Tchen et al., 2003; Conroy et al., 2013a; Koppelmans et al., 2012; Zimmer et al., 2015; Wefel et al., 2010; Hess et al., 2015; Hermelink et al., 2010; Tager et al., 2010; Deprez et al., 2012; Ahles et al., 2010; Jim et al., 2012; Hutchinson et al., ...
Source: Critical Reviews in Oncology Hematology - August 14, 2017 Category: Cancer & Oncology Authors: Milena Vitali, Carla Ida Ripamonti, Fausto Roila, Claudia Proto, Diego Signorelli, Martina Imbimbo, Giulia Corrao, Angela Brissa, Gallucci Rosaria, Filippo de Braud, Marina Chiara Garassino, Giuseppe Lo Russo Tags: Oncology reviews Source Type: research

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(Source: Critical Reviews in Oncology Hematology)
Source: Critical Reviews in Oncology Hematology - August 12, 2017 Category: Cancer & Oncology Source Type: research