The Impact of a Machine Learning Early Warning Score on Hospital Mortality: A Multicenter Clinical Intervention Trial
OBJECTIVES: To determine the impact of a machine learning early warning risk score, electronic Cardiac Arrest Risk Triage (eCART), on mortality for elevated-risk adult inpatients. DESIGN: A pragmatic pre- and post-intervention study conducted over the same 10-month period in 2 consecutive years. SETTING: Four-hospital community-academic health system. PATIENTS: All adult patients admitted to a medical-surgical ward. INTERVENTIONS: During the baseline period, clinicians were blinded to eCART scores. During the intervention period, scores were presented to providers. Scores greater than or equ...
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Persistent But Not Transient Acute Kidney Injury Was Associated With Lower Transplant-Free Survival in Patients With Acute Liver Failure: A Multicenter Cohort Study*
CONCLUSIONS: In a multicenter cohort of patients with ALF, persistent but not transient AKI was independently associated with lower short-term TFS. (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Impact of Pharmacists to Improve Patient Care in the Critically Ill: A Large Multicenter Analysis Using Meaningful Metrics With the Medication Regimen Complexity-ICU (MRC-ICU) Score*
OBJECTIVES: Despite the established role of the critical care pharmacist on the ICU multiprofessional team, critical care pharmacist workloads are likely not optimized in the ICU. Medication regimen complexity (as measured by the Medication Regimen Complexity-ICU [MRC-ICU] scoring tool) has been proposed as a potential metric to optimize critical care pharmacist workload but has lacked robust external validation. The purpose of this study was to test the hypothesis that MRC-ICU is related to both patient outcomes and pharmacist interventions in a diverse ICU population. DESIGN: This was a multicenter, observatio...
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Renin-Angiotensin System Pathway Therapeutics Associated With Improved Outcomes in Males Hospitalized With COVID-19*
CONCLUSIONS: ARBs use was associated with less ventilation and vasopressors in males but not females. Sex-based differences in RAS dysregulation may contribute to sex-based differences in outcomes and responses to ARBs in COVID-19. (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Daily Written Care Summaries for Families of Critically Ill Patients: A Randomized Controlled Trial*
CONCLUSIONS: Written communication improved satisfaction and the emotional well-being of families of critically ill patients, supporting its use as a supplement to traditional communication approaches. (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Casting Light on the Necessary, Expansive, and Evolving Role of the Critical Care Dietitian: An Essential Member of the Critical Care Team
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Invited Foreword Source Type: research

Stability of Spo2/Fio2 and Respiratory Rate-Oxygenation Indexes in Critical Respiratory Disorders
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Therapeutic Hyperthermia Is Associated With Improved Survival in Afebrile Critically Ill Patients With Sepsis: A Pilot Randomized Trial
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Fragility Index and Trial Sequential Analysis for Randomized Controlled Studies Testing IV Vitamin C in Critically Ill Patients
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Cerebral Tissue Oxygenation Monitoring for Guiding RBC Transfusion in Neurocritical Patients
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Hyperbaric Oxygenation Therapy Alone for Carbon Monoxide Poisoning: Time for Reinforcements?
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - July 16, 2022 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research