Long-Term Functional Outcome and Quality of Life Following In-Hospital Cardiac Arrest—A Longitudinal Cohort Study
Conclusions: The majority of in-hospital cardiac arrest survivors had a good functional outcome and health-related quality of life at 6 months, and this was largely unchanged at 12 months. Despite this, many reported problems with mobility, self-care, usual activities, pain, and anxiety/depression. Return to work rates was low, and hospital readmissions were common. (Source: Critical Care Medicine)
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients*
Conclusions: Although there was no significant difference in the performance of renin and lactate when examining the absolute values of each laboratory, a positive rate of change in renin concentration, but not lactate concentration, over 72 hours was associated with in-hospital mortality. For each one-unit increase in the slope of ln-renin, the odds of mortality increased 10-fold. Renin levels greater than 40 pg/mL, but not lactate levels greater than 2 mmol/L, were associated with in-hospital mortality. These findings suggest that plasma renin kinetics may be superior to lactate kinetics in predicting mortality of hy...
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Regionalization of Critical Care in the United States: Current State and Proposed Framework From the Academic Leaders in Critical Care Medicine Task Force of the Society of Critical Care Medicine*
Conclusions: Under the value-based paradigm, the goals are operational efficiency and patient outcomes. Health systems that can align strategy and operations to assist the referral hospitals with implementing regionalization will be better positioned to regionalize critical care effectively. (Source: Critical Care Medicine)
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Criteria for Pediatric Sepsis—A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce*
Objective: To determine the associations of demographic, clinical, laboratory, organ dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic shock in children with infection and 2) multiple organ dysfunction or death in children with sepsis, severe sepsis, or septic shock. Data Sources: MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched from January 1, 2004, and November 16, 2020. Study Selection: Case-control studies, cohort studies, and randomized controlled trials in children greater than or equal to 37-week-old postconception to 18...
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Racial Disparities in ICU Outcomes: A Systematic Review*
Conclusions: This systematic review found significant differences in the care and outcomes among ICU patients of different races. Mortality differences were largely explained by accompanying demographic and patient factors, highlighting the effect of structural inequalities on racial differences in mortality in the ICU. This systematic review provides evidence that structural inequalities in care persist in the ICU, which contribute to racial disparities in care. Future research should evaluate interventions to address inequality in the ICU. (Source: Critical Care Medicine)
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021: Erratum
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Errata Source Type: research

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients With Coronavirus Disease 2019: Erratum
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Errata Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Improved Survival Through Early Versus Late Impella Support for Myocardial Infarction–Related Shock? Mind Your Step!
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Implication of Early Impella Support in Postcardiac Arrest Cardiogenic Shock Complicating Acute Myocardial Infarction
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The Limitations of Standardized Mortality Ratios for Coronavirus Disease 2019 ICU Patients
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

The authors reply
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Motoric Subtypes of Delirium: Not Associated With Long-Term Outcomes in Adults After Critical Illness?
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - November 22, 2021 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research