Anisocoria and Poor Pupil Reactivity by Quantitative Pupillometry in Patients With Intracranial Pathology
CONCLUSIONS: New onset anisocoria occurs in over 60% of patients with neurologic emergencies. Pupil reactivity may be an important distinguishing characteristic of clinically relevant new onset anisocoria phenotypes. New onset anisocoria accompanied by objective evidence of abnormal pupil reactivity was associated with midline shift, and new onset anisocoria accompanied by objective evidence of normal pupil reactivity had an inverse relationship with death. Distinct quantitative pupil characteristics precede new onset anisocoria occurrence and may allow for earlier prediction of neurologic decline. Further work is need...
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Targeted Temperature Management in Out-of-Hospital Cardiac Arrest With Shockable Rhythm: A Post Hoc Analysis of the Coronary Angiography After Cardiac Arrest Trial
CONCLUSIONS: In the context of out-of-hospital cardiac arrest with shockable rhythm and no ST-elevation, treatment with mild therapeutic hypothermia was not associated with improved 90-day survival compared with targeted normothermia. Neurologic outcomes at 90 days as well as patient-reported Mental and Physical Health Scores at 1 year did not differ between the groups. (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Association of Socioeconomic Status With Postdischarge Pediatric Resource Use and Quality of Life
This study examines the associations between socioeconomic status, resource use, and health-related quality of life in a cohort of children recovering from acute respiratory failure. DESIGN: Secondary analysis of data from the Randomized Evaluation of Sedation Titration for Respiratory Failure clinical trial. SETTING: Thirty-one PICUs. PATIENTS: Children with acute respiratory failure enrolled whose parent/guardians consented for follow-up. MEASUREMENTS AND MAIN RESULTS: Resource use included in-home care, number of healthcare providers, prescribed medications, home medical equipment, emergency ...
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Evaluating the Balance Between Privacy and Access in Digital Information Sharing
CONCLUSIONS: In the context of an ICU admission, sharing personal health information with a person of the patient’s choosing appears desirable for most patients and family members. Policies and implementation of regulations should take this into consideration. (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Online Editorial Board Acknowledgment
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorial Board Acknowledgment Source Type: research

Pediatric Delirium: We Have Come a Long Way, and We Have Only Just Begun*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

How Much Fluid Should I Give to My Patient on a Ventilator?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Further Exploration of MARS*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

The Role of the Long-Term Acute Care Hospital Following Critical Illness—Has the Coronavirus Disease 2019 Pandemic Demonstrated Their Usefulness or Emphasized Their Downside?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Are We Still Withdrawing Too Soon?—Predictors of Late Awakening After Cardiac Arrest*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

The Big Consequences of Small Discrepancies: Why Racial Differences in Pulse Oximetry Errors Matter*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Editorials Source Type: research

Continuous Versus Routine Standardized Electroencephalogram for Outcome Prediction in Critically Ill Adults: Analysis From a Randomized Trial
CONCLUSIONS: Standardized EEG interpretation provides reliable prognostic information. Continuous EEG provides more information than routine EEG. (Source: Critical Care Medicine)
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Brief Report Source Type: research

A Systematic Review and Pooled Prevalence of Delirium in Critically Ill Children*
CONCLUSIONS: Pediatric delirium, as determined by the Cornell Assessment of Pediatric Delirium score, is estimated to occur in 34% of critical care admissions. Eight of 11 studies reporting on subtype identified hypoactive delirium as most prevalent (46–81%) with each of the three remaining reporting either hyperactive (44%), mixed (57%), or equal percentages of hypoactive and mixed delirium (43%) as most prevalent. The development of pediatric delirium is associated with cumulative doses of benzodiazepines, opioids, the number of sedative classes used, deep sedation, and cardiothoracic surgery. Increased time mechan...
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Review Article Source Type: research

Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China: A Nested Case-Control Study*
This study investigated the dose-response relationship between fluid balance and ventilator-associated events. DESIGN: Nested case-control study. SETTING: The study was based on a well-established, research-oriented registry of healthcare-associated infections at ICUs of West China Hospital system (Chengdu, China). PATIENTS: A total of 1,528 ventilator-associated event cases with 3,038 matched controls, who consistently underwent mechanical ventilation for at least 4 days from April 1, 2015, to December 31, 2018, were included. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: We calcul...
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research