Missed opportunities in coronary artery disease: reflection on practice to improve patient outcomes
Missed opportunities refer to incidents where different actions by those involved could result in more desirable outcomes. While missed opportunities are not an established concept in coronary artery disease (CAD), they are important because CAD is common and potentially life-threatening. Treatment of CAD has the potential to prevent poor patient outcomes which can have a downstream consequence on resource utilization and costs for healthcare providers. The missed opportunities in CAD could be divided into those related to prevention, early detection, diagnosis and treatment. The primary prevention opportunities include th...
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Review in Depth in CAD Source Type: research
Contemporary use of anticoagulation in the cardiac catheterization laboratory: a review
Anticoagulation during percutaneous coronary interventions has a rich history that has been shaped by several key clinical trials. The correct choice of anticoagulation during interventions can maximize patient outcomes and ensure a safe procedure. However, in some specific situations, anticoagulation may not be required at all. In this review article, we review the significant clinical trials and current guidelines regarding the use of anticoagulation in the catheterization laboratory and discuss the unique pharmacological aspects of the most commonly used agents, with an emphasis on the specific pharmacokinetic parameter...
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Review in Depth in CAD Source Type: research
Prediction of risk for bleeding, myocardial infarction and mortality after percutaneous coronary intervention in patients with acute coronary syndromes
This study included 3377 patients with ACS who underwent PCI in the setting of the ISAR-REACT 5 trial. Patients with bleeding, MI or those dying at 1 year after PCI were characterized in terms of baseline characteristics, risk estimates and C-statistic of the risk prediction models for these outcomes.
Results
Major bleeding (Bleeding Academic Research Consortium types 3–5), MI and mortality occurred in 195 patients (5.8%), 143 patients (4.3%) and 143 patients (4.3%), respectively. After adjustment, bleeding [hazard ratio = 5.08; 95% confidence interval (CI), 3.03–8.53; P (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Residual SYNTAX II Score and long-term outcomes post-ST-elevation myocardial infarction in an urban US cohort: the Montefiore STEMI Registry
Conclusions
In summary, higher rSS-II was associated with long-term outcomes post-STEMI in a prospective urban, minority cohort, suggesting a potential role for risk stratification with this measure in a non-trial setting. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Early vascular healing after implantation of the polymer-free biolimus-eluting stent or the ultrathin strut biodegradable polymer sirolimus-eluting stent in patients with ST-segment elevation myocardial infarction
Conclusion
In patients with STEMI, the drug-coated BF-BES and the thin strut O-SES had similar vascular healing index at 1-month. However, the thin O-SES struts were more often malapposed. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Coronary artery calcium score above 250 confirms the presence of significant stenosis in coronary CT angiography of symptomatic patients
This study aims to investigate if there are a correlation and statistical significance between different CACS cutoffs and the severity of coronary artery stenosis by coronary CT angiography (CCTA) in symptomatic patients.
Methods
This is a retrospective study that included all symptomatic patients who had CCTA in a tertiary care hospital over a period of 7 years.
Results
CCTA of 502 patients was evaluated (406 included, mean age 56.2 years); 230 were males (56.7%). The prevalence of stenosis at any percentage was 53.7%, ≥50% was 26.6% and ≥70% was 12.3%. The mean CACS was 84.5 (range 0–1860), for ma...
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Analysis of clinical risk models vs. clinician’s assessment for prediction of coronary artery disease among predominantly female population
Introduction
Multiple risk models are used to predict the presence of obstructive coronary artery disease (CAD) in patients with chest pain. We aimed to compare the performance of these models to an experienced cardiologist’s assessment utilizing coronary angiography (CA) as a reference.
Materials and methods
We prospectively enrolled patients without known CAD referred for elective CA. We assessed pretest probability of CAD using the following risk models: Diamond–Forrester (original and updated), Duke Clinical score, ACC/AHA, CAD consortium (basic and clinical) and PROMISE minimal risk tool. All patients c...
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Low attenuation plaque volume on coronary computed tomography angiography is associated with plaque progression
Conclusion
Only a high baseline LAP volume was associated with plaque progression, and patients with progressive plaques and a high LAP volume were more likely to have future MACEs. More attention should be given to plaques with LAP volumes larger than 2.4 mm3. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Very long-term outcomes of older adults with stable coronary artery disease (from the CORONOR study)
Background
There are limited data on stable coronary artery disease (CAD) in the very elderly. The present study aimed to investigate incident cardiovascular events and mortality in older adults (≥85 years) included in a multicenter registry on stable CAD.
Methods
A long-term follow-up was performed in 198 patients ≥85 years with stable CAD, free from myocardial infarction (MI) or coronary revascularization within the year. The median age was 87 years. Clinical events during the follow-up period [death, MI, ischemic stroke, coronary revascularization and hospitalization for heart failure (HF)] were centrally...
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Impact of glomerular filtration rate estimation on cardiovascular events in elderly patients undergoing coronary angiography
Conclusions
Kidney function, as manifested by eGFR, has a graded inverse association with the burden of cardiovascular comorbidities and long-term adverse events in elderly patients undergoing coronary angiography. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - April 8, 2022 Category: Cardiology Tags: Original Research in CAD Source Type: research
Erosion and thrombus organization as a potential cause of very late stent failure after the implantation of the first-generation sirolimus-eluting stents: in-vivo multimodality imaging assessment
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - February 3, 2022 Category: Cardiology Tags: Images in CAD Source Type: research
Drill and blast: acute stent regret treated with roto-tripsy
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - February 3, 2022 Category: Cardiology Tags: Images in CAD Source Type: research
Anomalous interarterial right coronary artery culprit vessel in ST-segment elevation myocardial infarction
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - February 3, 2022 Category: Cardiology Tags: Images in CAD Source Type: research
Impact of tube angulations and imaging mode on radiation dosage using image noise reduction technology
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - February 3, 2022 Category: Cardiology Tags: Research communications Source Type: research
Pronounced late acquired focal coronary artery dilatation after paclitaxel-coated balloon angioplasty: observations from the randomized REVascularization With PaclitaxEL-Coated Balloon Angioplasty Versus Drug-Eluting Stenting in Acute Myocardial InfarcTION (REVELATION) trial
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - February 3, 2022 Category: Cardiology Tags: Research communications Source Type: research
