Colchicine therapy in patients with coronary artery disease: a systematic review and meta-analysis of randomized controlled trials
Conclusion This meta-analysis suggests that colchicine was not associated with a significant decrease in cardiovascular endpoints and mortality in patients with CAD. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: Reviews and Meta-Analyses in CAD Source Type: research

SMARTphone-based, early cardiac REHABilitation in patients with acute coronary syndromes: a randomized controlled trial
Background There are well-documented treatment gaps in secondary prevention of coronary heart disease with a lack of clearly defined strategies to assist early physical activity after acute coronary syndromes (ACS). Smartphone technology may provide an innovative platform to close these gaps. Objectives The primary goal of this study was to assess whether a smartphone-based, early cardiac rehabilitation program improved exercise capacity in patients with ACS. Methods A total of 206 patients with ACS across six tertiary Australian hospitals were included in this randomized controlled trial. Participants we...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: POST-MI CARE/Rehabiliation Source Type: research

Benefits of early administration of Sacubitril/Valsartan in patients with ST-elevation myocardial infarction after primary percutaneous coronary intervention
Conclusion Patients with ST-elevation myocardial infarction after primary percutaneous coronary intervention could benefit from early administration of Sacubitril/Valsartan, the effect was superior to conventional ACEI. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: POST-MI CARE/Rehabiliation Source Type: research

Effects of sacubitril/valsartan on ventricular remodeling in patents with left ventricular systolic dysfunction following acute anterior wall myocardial infarction
Objective The aim of this study was to investigate the effect of sacubitril/valsartan (Sal/Val) on left ventricular (LV) remodeling in patients with LV systolic dysfunction following acute anterior wall myocardial infarction (AAMI). Methods AAMI patients with LV systolic dysfunction were enrolled in this study. All patients underwent percutaneous coronary intervention. After hemodynamic stabilization, patients were randomly assigned either to group T (Sal/Val treatment) or group C (enalapril treatment). Changes in echocardiographic parameters and plasma biochemical markers were used to evaluate the effects of Sa...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: POST-MI CARE/Rehabiliation Source Type: research

Perioperative safety of simultaneous off-pump coronary artery bypass grafting with non-cardiac surgery of moderate-to-severe severity
Background To evaluate the perioperative safety of simultaneous off-pump coronary artery bypass grafting (OPCABG) with non-cardiac surgery. Methods From September 2013 to January 2019, patients who underwent OPCABG surgery in the Department of Cardiology, Peking University First Hospital were included in this retrospective study. A total of 54 patients who underwent simultaneous surgery were defined as simultaneous surgery group. A total of 108 patients who had recently undergone isolated OPCABG surgery, and had similar vascular reconstruction methods were selected for matching, and these patients were defined a...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: CABG Source Type: research

Physician prediction of 1-year mortality in the cardiac catheterization laboratory: comparison to a validated risk score
Background Physician perception of procedural risk and clinical outcome can affect revascularization decision making. Public reporting of percutaneous coronary intervention outcomes accentuates the need for accuracy in risk prediction in order to avoid a treatment paradox of undertreating the highest risk patients. Our study compares a validated risk score to physician prediction (PP) of 1-year mortality based on clinical impression at the time of invasive angiography. Methods and results We performed a cohort study between August 2015 and May 2018 to determine the discriminative accuracy of interventional cardi...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: PCI Source Type: research

Avoiding the emergence of contrast-induced acute kidney injury in acute coronary syndrome: routine hydration treatment
Background: Patients with acute coronary syndrome (ACS) have about a three-fold risk for developing contrast-induced acute kidney injury(CI-AKI). Investigating studies on routine hydration therapy have frequently included patients with stable coronary artery disease and high risk of CI-AKI [estimated glomerular filtration rate (eGFR)  (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: PCI Source Type: research

One-year performance of thin-strut cobalt chromium sirolimus-eluting stent versus thicker strut stainless steel biolimus-eluting coronary stent: a propensity-matched analysis of two international all-comers registries
Conclusions These findings suggest an improved clinical safety and efficacy of a newer generation thin-strut SES as compared with a second-generation thicker strut BES. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: PCI Source Type: research

Stent strut thickness and acute vessel injury during percutaneous coronary interventions: an optical coherence tomography randomized clinical trial
Conclusion There was no difference in the extent of OCT-based vessel injury associated with thin and thick-strut DES platforms. TP was larger with the thin strut DES, potentially reflecting a deeper stent embedment in the vessel wall. (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: PCI Source Type: research

Pre-infarction angina is associated with improved prognosis in diabetic patients with ST-elevation myocardial infarction – data from a contemporary cohort
Background Pre-infarction angina (PIA) is associated with improved prognosis in patients with ST-elevation myocardial infarction (STEMI). Some studies suggest that diabetes may blunt the effect of ischaemic preconditioning. We sought to study the impact of PIA in diabetic patients with STEMI. Methods Consecutive patients with STEMI who underwent primary angioplasty were included. PIA was defined as ≥1 episode of chest pain during the week preceding STEMI diagnosis. Incident major adverse cardiovascular events (MACE) were defined as the first occurrence of all-cause death, stroke or acute myocardial infarction....
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: Myocardial Infarction Source Type: research

The evolving pandemic of COVID-19 and increasing role of cardiac computed tomography
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: COVID-19 and CAD Source Type: research

The relationship between coronary artery disease and clinical outcomes in COVID-19: a single-center retrospective analysis
Introduction Recent studies have reported evidence that coronavirus disease 2019 (COVID-19) has disproportionately affected patients with underlying comorbidities. Our study aims to evaluate the impact of both cardiac and noncardiac comorbidities on a high-risk population with COVID-19 infection and coronary artery disease (CAD) compared to those without CAD. Methods This is a retrospective study of patients who tested COVID-19 positive via reverse transcriptase-PCR (RT-PCR) assay. We compared the characteristics and outcomes of patients with and without CAD. Population demographics, comorbidities and clinical o...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: COVID-19 and CAD Source Type: research

Prognostic significance of cardiac injury in COVID-19 patients with and without coronary artery disease
Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome have not been well-defined yet. The aim of this study is to delineate the prognostic importance of presence of concomitant cardiac injury on admission in patients with COVID-19. Methods For this multi-center retrospective study, data of consecutive patients who were treated for COVID-19 between 20 March and 20 April 2020 were collected. Clinical characteristics, laboratory findings and outcomes data were obtained from electronic medical records. In-hospital clinical outcome was compared between patients with and with...
Source: Coronary Artery Disease - July 27, 2021 Category: Cardiology Tags: COVID-19 and CAD Source Type: research

Anomalous origin of the left coronary artery from the right coronary artery with trans-septal course: a rare case report
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - May 6, 2021 Category: Cardiology Tags: Images in Coronary Artery Disease Source Type: research

Spontaneous coronary artery dissection in a patient with COVID-19
No abstract available (Source: Coronary Artery Disease)
Source: Coronary Artery Disease - May 6, 2021 Category: Cardiology Tags: Images in Coronary Artery Disease Source Type: research