Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research

Development of Multivariable Prediction Models for the Identification of Patients Admitted to Hospital with an Exacerbation of COPD and the Prediction of Risk of Readmission: A Retrospective Cohort Study using Electronic Medical Record Data
CONCLUSION: We generated clinical prediction models to identify AECOPDs during hospitalization and to predict 30-day readmissions after an acute exacerbation from a dataset derived from available EMR data. Further work is needed to improve and externally validate these models.PMID:37555513 | DOI:10.1080/15412555.2023.2242493 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Reza Fakhraei John Matelski Andrea Gershon Tetyana Kendzerska Lauren Lapointe-Shaw Lanujan Kaneswaran Robert Wu Source Type: research

Statins and Mortality in COPD: A Methodological Review of Observational Studies
In conclusion, the observational studies investigating statin use and mortality in COPD are affected by major biases, many of which can result in spurious protective effects. Well-designed observational studies that carefully emulate randomized trials are needed to resolve this uncertainty regarding the potential beneficial benefits of statins on mortality in patients with COPD.PMID:37555454 | DOI:10.1080/15412555.2023.2242489 (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - August 9, 2023 Category: Respiratory Medicine Authors: Naheemot Olaoluwa Sule Samy Suissa Source Type: research