Interaction of 8-Anilinonaphthalene-1-Sulfonate with SARS-CoV-2 main protease and its application as a fluorescent probe for inhibitor identification
Publication date: Available online 5 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Peerapon Deetanya, Kowit Hengphasatporn, Patcharin Wilasluck, Yasuteru Shigeta, Thanyada Rungrotmongkol, Kittikhun Wangkanont (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 7, 2021 Category: Biotechnology Source Type: research

Functional and structural investigation of N-terminal domain of the SpTad2/3 heterodimeric tRNA deaminase
Publication date: Available online 5 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Xiwen Liu, Jie Zhou, Ruiguang Ge, Wei Xie (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 7, 2021 Category: Biotechnology Source Type: research

Protein Conformational Switch Discerned via Network Centrality Properties
Publication date: Available online 5 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): David Foutch, Bill Pham, Tongye Shen (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 7, 2021 Category: Biotechnology Source Type: research

Genetic mapping of developmental trajectories for complex traits and diseases
Publication date: Available online 6 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Eldad David Shulman, Ran Elkon (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 7, 2021 Category: Biotechnology Source Type: research

Leri: a web-server for identifying protein functional networks from evolutionary couplings
Publication date: Available online 6 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Ngaam J. Cheung, Arun T. John Peter, Benoit Kornmann (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 7, 2021 Category: Biotechnology Source Type: research

Structural and functional characterization of the receptor binding proteins of Escherichia coli O157 phages EP75 and EP335
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Sander Witte, Léa V. Zinsli, Rafael Gonzalez-Serrano, Cassandra I. Matter, Martin J. Loessner, Joël T. van Mierlo, Matthew Dunne (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Shujiro Okuda, Yoshifumi Shimada, Yosuke Tajima, Kizuki Yuza, Yuki Hirose, Hiroshi Ichikawa, Masayuki Nagahashi, Jun Sakata, Yiwei Ling, Nobuaki Miura, Mika Sugai, Yu Watanabe, Shiho Takeuchi, Toshifumi Wakai (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

Pleiotropic Roles of Late Embryogenesis Abundant Proteins of Deinococcus radiodurans against Oxidation and Desiccation
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Yingying Liu, Chen Zhang, Zhihan Wang, Min Lin, Jin Wang, Min Wu (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

A Fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Pooja Gupta, Sherine E. Thomas, Shaymaa A. Zaidan, Maria A. Pasillas, James Cory-Wright, Víctor Sebastián-Pérez, Ailidh Burgess, Emma Cattermole, Clio Meghir, Chris Abell, Anthony G. Coyne, William R. Jacobs, Tom L. Blundell, Sangeeta Tiwari, Vítor Mendes (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

Binding Characteristics of Staphylococcal Protein A and Streptococcal Protein G for Fragment Crystallizable Portion of Human Immunoglobulin G
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Hae Gon Lee, Shinill Kang, Joon Sang Lee (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

Strategies for mitochondrial gene editing
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Xingbo Yang, Jiacheng Jiang, Zongyu Li, Jiayi Liang, Yaozu Xiang (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

The Mechanism of Activation of Monomeric B-Raf V600E
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Ryan C. Maloney, Mingzhen Zhang, Hyunbum Jang, Ruth Nussinov (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 6, 2021 Category: Biotechnology Source Type: research

Dissecting nucleotide selectivity in viral RNA polymerases
Publication date: Available online 4 June 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Chunhong Long, Moises Ernesto Romero, Daniel La Rocco, Jin Yu (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - June 4, 2021 Category: Biotechnology Source Type: research

scDA: single cell discriminant analysis for single-cell RNA sequencing data
Publication date: Available online 29 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Qianqian Shi, Xinxing Li, Qirui Peng, Chuanchao Zhang, Luonan Chen (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 30, 2021 Category: Biotechnology Source Type: research

A novel approach for studying receptor-ligand interactions on living cells surface by using NUS/T1ρ-NMR methodologies combined with computational techniques: the RGDechi15D-αvβ5 integrin complex
Publication date: Available online 29 May 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Biancamaria Farina, Corvino Andrea, Annarita Del Gatto, Daniela Comegna, Sonia Di Gaetano, Domenica Capasso, Antonella Paladino, Clementina Acconcia, Maria Teresa Gentile, Michele Saviano, Roberto Fattorusso, Laura Zaccaro, Luigi Russo (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - May 30, 2021 Category: Biotechnology Source Type: research