Usefulness of the Clavien-Dindo Classification to rate complications after carotid endarterectomy and its implications in patient prognosis.
z-Blancas M Abstract OBJECTIVE: Our primary objective was to test if the C-D-C is also applicable for the assessment of carotid surgery and how well it correlates with patient prognosis in the mid-term follow-up. METHODS: From January 2011 to March 2014, a total of 248 consecutive open surgical carotid revascularization procedures were performed at one academic institution. All patients, symptomatic and asymptomatic, had a high-grade (>70%) stenosis and were operated on under general anesthesia. Physicians graded all complications that were identified in the first 30 days after surgery according to C-D-C(9...
Source: cmaj - September 11, 2018 Category: General Medicine Authors: Inaraja-Pérez GC, Júlvez-Blancas M Tags: Ann Vasc Surg Source Type: research

Clinical implications of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
PMID: 30201611 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Fernando SM, Rochwerg B, Seely AJE Tags: CMAJ Source Type: research

We need smarter trigger tools for diagnosing sepsis in children in Canada.
PMID: 30201612 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Ansermino JM, Wiens MO, Kissoon N Tags: CMAJ Source Type: research

Susceptible period for cardiovascular complications in patients recovering from sepsis.
Abstract BACKGROUND: Patients are at increased risk of cardiovascular complications while recovering from sepsis. We aimed to study the temporal change and susceptible periods for cardiovascular complications in patients recovering from sepsis by using a national database. METHODS: In this retrospective population-based cohort study, patients with sepsis were identified from the National Health Insurance Research Database in Taiwan. We estimated the risk of myocardial infarction (MI) and stroke following sepsis by comparing a sepsis cohort to a matched population and hospital control cohort. The primary outco...
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Lai CC, Lee MG, Lee WC, Chao CC, Hsu TC, Lee SH, Lee CC, National Taiwan University Hospital Health Data Science Research Group Tags: CMAJ Source Type: research

Renal complications and subsequent mortality in acute critically ill patients without pre-existing renal disease.
Abstract BACKGROUND: Most studies of long-term renal outcomes after acute critical illness have enrolled patients with pre-existing renal dysfunction. We assessed renal outcomes in patients who did not have pre-existing renal disease and who were admitted to hospital for acute critical illness. METHODS: We identified adults who did not have pre-existing renal disease and who were admitted to hospital for acute critical illness between 2000 and 2011, from the Taiwan National Health Insurance Research Database. Each patient was matched 1:2 with controls without acute critical illness, according to age, sex and ...
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Huang ST, Ke TY, Chuang YW, Lin CL, Kao CH Tags: CMAJ Source Type: research

A 38-year-old man with fever and a history of malaria.
PMID: 30201615 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Redditt V, Bogoch I, Rashid M Tags: CMAJ Source Type: research

Sepsis-associated encephalopathy.
OW PMID: 30201616 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Helbing DL, Böhm L, Witte OW Tags: CMAJ Source Type: research

Invasive pneumococcal infection in a man with hyposplenism.
PMID: 30201617 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Yoshimura S, Yoon HS Tags: CMAJ Source Type: research

Early referral for hoarseness.
PMID: 30201618 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Gevorgyan CA Tags: CMAJ Source Type: research

Hoarseness of unclear origin may be a sign of cerebrovascular disease and herald impending recurrent brainstem stroke.
PMID: 30201619 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Fraser JA Tags: CMAJ Source Type: research

Canadian health care lacks culture of innovation.
PMID: 30201620 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Medical technology often a burden if designed without physician input.
PMID: 30201621 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Emotions flare in tense but civil CMA annual meeting.
PMID: 30201622 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 10, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Minimizing the adverse public health effects of cannabis legalization.
PMID: 30181148 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Hall W Tags: CMAJ Source Type: research

Absolute 10-year risk of dementia by age, sex and APOE genotype: a population-based cohort study.
dt R Abstract BACKGROUND: Dementia is a major cause of disability, and risk-factor reduction may have the potential to delay or prevent the disease. Our aim was to determine the absolute 10-year risk of dementia, by age, sex and apolipoprotein E (APOE) genotype. METHODS: We obtained data from the Copenhagen General Population Study (from 2003 to 2014) and the Copenhagen City Heart Study (from 1991 to 1994 and 2001 to 2003). Participants underwent a questionnaire, physical examination and blood sampling at baseline. Diagnoses of dementia and cerebrovascular disease were obtained from the Danish National Patien...
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Rasmussen KL, Tybjærg-Hansen A, Nordestgaard BG, Frikke-Schmidt R Tags: CMAJ Source Type: research

How predatory journals leak into PubMed.
PMID: 30181150 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Manca A, Moher D, Cugusi L, Dvir Z, Deriu F Tags: CMAJ Source Type: research

Vaccine-associated measles in a healthy 40-year-old woman.
PMID: 30181151 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Churchill L, Rizzuti FA, Fonseca K, Kim J Tags: CMAJ Source Type: research

Black esophagus: acute esophageal necrosis complicating diabetic ketoacidosis.
PMID: 30181152 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Haghbayan H, Sarker AK, Coomes EA Tags: CMAJ Source Type: research

Canada Food Guide's focus on reducing saturated fat contradicts evidence.
PMID: 30181153 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Bradshaw BA, Loffelmann C Tags: CMAJ Source Type: research

EHR access and training still lacking for medical trainees.
PMID: 30181154 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Part-time doctors - reducing hours to reduce burnout.
PMID: 30181155 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Glauser W Tags: CMAJ Source Type: research

Many Canadian health facilities unprepared for disasters.
PMID: 30181156 [PubMed - in process] (Source: cmaj)
Source: cmaj - September 4, 2018 Category: General Medicine Authors: Vogel L Tags: CMAJ Source Type: research

What we need to learn about multimorbidity.
PMID: 30150240 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Flegel K Tags: CMAJ Source Type: research

Considerations for clinical trials to study cannabinoids in Canadian children with neurologic disorders.
PMID: 30150241 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Kelly LE, Junker A Tags: CMAJ Source Type: research

Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis.
Abstract INTRODUCTION: More than half of older adults (age ≥ 65 yr) have 2 or more high-burden multimorbidity conditions (i.e., highly prevalent chronic diseases, which are associated with increased health care utilization; these include diabetes [DM], dementia, depression, chronic obstructive pulmonary disease [COPD], cardiovascular disease [CVD], arthritis, and heart failure [HF]), yet most existing interventions for managing chronic disease focus on a single disease or do not respond to the specialized needs of older adults. We conducted a systematic review and meta-analysis to identify effective multimorbid...
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Kastner M, Cardoso R, Lai Y, Treister V, Hamid JS, Hayden L, Wong G, Ivers NM, Liu B, Marr S, Holroyd-Leduc J, Straus SE Tags: CMAJ Source Type: research

Hemolytic anemia in a 26-year-old woman with vomiting and fatigue.
PMID: 30150243 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Elharram M, Sapon-Cousineau V, Tagalakis V Tags: CMAJ Source Type: research

Subungual melanoma.
PMID: 30150244 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Jalali BK, Kreuter A Tags: CMAJ Source Type: research

The impact of neglecting unearned advantage.
PMID: 30150245 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Green S, Nixon S Tags: CMAJ Source Type: research

Poverty as a medical condition.
PMID: 30150246 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Fuller J, Loganathan M Tags: CMAJ Source Type: research

A forgotten vulnerable group: Canadian children visiting relatives in the developing world.
PMID: 30150247 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Zimmer R Tags: CMAJ Source Type: research

Cancellation of basic income project a blow to health research.
PMID: 30150248 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Is it unprofessional for doctors to have tattoos or facial piercings?
PMID: 30150249 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Motluk A Tags: CMAJ Source Type: research

CMA "effectively abandoning" role as national voice on physician issues, says Ontario Medical Association.
CMA "effectively abandoning" role as national voice on physician issues, says Ontario Medical Association. CMAJ. 2018 Aug 27;190(34):E1028-E1029 Authors: Vogel L PMID: 30150250 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 27, 2018 Category: General Medicine Authors: Vogel L Tags: CMAJ Source Type: research

Withdrawal of Saudi trainees exposes vulnerability of Canadian health care.
PMID: 30131365 [PubMed - as supplied by publisher] (Source: cmaj)
Source: cmaj - August 21, 2018 Category: General Medicine Authors: Khan MH, Abdullah N, Stanbrook MB Tags: CMAJ Source Type: research

Integrating supervised consumption into a continuum of care for people who use drugs.
PMID: 30087127 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Scheim A, Werb D Tags: CMAJ Source Type: research

Mortality effects of timing alternatives for hip fracture surgery.
Abstract BACKGROUND: The appropriate timing of hip fracture surgery remains a matter of debate. We sought to estimate the effect of changes in timing policy and the proportion of deaths attributable to surgical delay. METHODS: We obtained discharge abstracts from the Canadian Institute for Health Information for hip fracture surgery in Canada (excluding Quebec) between 2004 and 2012. We estimated the expected population-average risks of inpatient death within 30 days if patients were surgically treated on day of admission, inpatient day 2, day 3 or after day 3. We weighted observations with the inverse propen...
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Sobolev B, Guy P, Sheehan KJ, Kuramoto L, Sutherland JM, Levy AR, Blair JA, Bohm E, Kim JD, Harvey EJ, Morin SN, Beaupre L, Dunbar M, Jaglal S, Waddell J, Canadian Collaborative Study of Hip Fractures Tags: CMAJ Source Type: research

Hypoxemia from patent foramen ovale in a 65-year-old woman with carcinoid heart disease.
PMID: 30087129 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Yang C, Sharma A Tags: CMAJ Source Type: research

Balo concentric sclerosis in a 23-year-old man.
PMID: 30087130 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Yang YC, Tsai CH Tags: CMAJ Source Type: research

Is there a real increased risk of stroke in patients with dengue fever?
PMID: 30087131 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Joob B, Wiwanitkit V Tags: CMAJ Source Type: research

The authors respond to "Is there a real increased risk of stroke in patients with dengue fever?"
The authors respond to "Is there a real increased risk of stroke in patients with dengue fever?" CMAJ. 2018 Aug 07;190(31):E941 Authors: Li HM PMID: 30087132 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Li HM Tags: CMAJ Source Type: research

Rise of women in medicine not matched by leadership roles.
Authors: PMID: 30087133 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Tags: CMAJ Source Type: research

Mortgage lenders increasingly targeting "financially naive" young doctors.
Mortgage lenders increasingly targeting "financially naive" young doctors. CMAJ. 2018 Aug 07;190(31):E943-E944 Authors: Collier R PMID: 30087134 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Collier R Tags: CMAJ Source Type: research

Most doctors lack adequate training to give informed diet advice.
PMID: 30087135 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Vogel L Tags: CMAJ Source Type: research

Medicine is one of the loneliest professions.
PMID: 30087136 [PubMed - in process] (Source: cmaj)
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Vogel L Tags: CMAJ Source Type: research

Responsible reporting to prevent suicide contagion.
PMID: 30061323 [PubMed - in process] (Source: cmaj)
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Colman I Tags: CMAJ Source Type: research

The association between suicide deaths and putatively harmful and protective factors in media reports.
Abstract BACKGROUND: Exposure to media reporting on suicide can lead to suicide contagion and, in some circumstances, may also lead to help-seeking behaviour. There is limited evidence for which specific characteristics of media reports mediate these phenomena. METHODS: This observational study examined associations between putatively harmful and protective elements of media reports about suicide in 13 major publications in the Toronto media market and subsequent suicide deaths in Toronto (2011-2014). We used multivariable logistic regression to determine whether specific article characteristics were associat...
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Sinyor M, Schaffer A, Nishikawa Y, Redelmeier DA, Niederkrotenthaler T, Sareen J, Levitt AJ, Kiss A, Pirkis J Tags: CMAJ Source Type: research

How placebo characteristics can influence estimates of intervention effects in trials.
PMID: 30061325 [PubMed - in process] (Source: cmaj)
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Howick J, Hoffmann T Tags: CMAJ Source Type: research

Monilethrix.
PMID: 30061326 [PubMed - in process] (Source: cmaj)
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Zhi HL, Liu ZH Tags: CMAJ Source Type: research

Daily analgesia for nonheadache pain may not lead to daily rebound headaches.
PMID: 30061327 [PubMed - in process] (Source: cmaj)
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Blitzer S Tags: CMAJ Source Type: research

Look for an underlying cause of headache.
PMID: 30061328 [PubMed - in process] (Source: cmaj)
Source: cmaj - July 30, 2018 Category: General Medicine Authors: Zitney M Tags: CMAJ Source Type: research