Oxidative Stress as a Risk Factor for Hearing Changes in HIV-positive Normal Listeners
CONCLUSION: Normal-hearing HIV+ individuals (with and without exposure to HAART) presented with poor performance in the audiological procedures, suggesting the presence of auditory alterations even in the presence of normal-hearing thresholds. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Morphometric and Molecular Muscle Remodeling after Passive Stretching in Elderly Female Rats
CONCLUSION: Three sessions of static stretching reduced the gene expression level of TGF- β 1, which, owing to its anti-fibrotic role, might contribute to the remodeling of the intramuscular connective tissue of the aging muscle. In addition, immunostaining revealed that TNF- α levels increased in the aging muscle tissue in response to stretching, indicating its effect on stimulating extracellular matrix degradation. These outcomes have important clinical implications in reinforcing the use of stretching exercises in the elderly, considering that the aging muscle presents an infiltration of connective tissue. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Therapeutic Education Program for Children and Adolescents with chronic diseases - Letter to the Editor
(Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Agile response to the shortage of personal protective equipment during the COVID-19 crisis
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Computing systems, telehealth, and personal data: what is up?
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Anti-Helicobacter pylori treatment can effectively improve the clinical remission rates of irritable bowel syndrome: a controlled clinical trial meta-analysis
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
COVID-19 and Liver Damage: Narrative Review and Proposed Clinical Protocol for Critically ill Pediatric Patients
SARS-CoV-2 shares nearly 80% of its ’ genomic sequence with SARS-CoV and MERS-CoV, both viruses known to cause respiratory symptoms and liver impairment. The emergence of pediatric cases of multisystem inflammatory syndrome related to the SARS-CoV-2 infection (PIM-TS) has raised concerns over the issue of hepatic damage and liver enzyme elevation in the critically ill pediatric population with COVID-19. Some retrospective cohorts and case series have shown various degrees of ALT/AST elevation in SARS-CoV-2 infections. A limited number of liver histopathological studies are available that show focal hepatic periportal ne...
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey
CONCLUSION: Our findings confirm that Graves ’ disease might trigger restless legs-like symptoms, while the condition of hyperthyroidism could also be complicated by definite RLS. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Long-term survival analysis after endoscopic stenting as a bridge to surgery for malignant colorectal obstruction: comparison with emergency diverting colostomy
Conclusions: No differences in disease-free and overall survival rates were observed in the five-year analysis of patients with resectable colorectal cancer who had undergone SEMS placement or colostomy for the treatment of malignant colorectal obstruction. Patients in the SEMS group had a higher rate of primary anastomosis and a lower rate of temporary colostomy than did those in the surgery group. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Quality of life among total laryngectomized patients undergoing speech rehabilitation: correlation between several instruments
CONCLUSION: The EORTC QLQ-C30, EORTC QLQ-H&N35 and UW-QOL were the instruments that most correlated with the remaining instruments, indicating that any of the three can be used to assess the quality of life of the target population regardless of oesophageal voice development. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Continuous suprascapular nerve block compared with single-shot interscalene brachial plexus block for pain control after arthroscopic rotator cuff repair
CONCLUSION: C-SSNB was more effective than S-ISNB at 6 − 12 h after the surgery for postoperative analgesia after arthroscopic rotator cuff repair. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Vestibular evoked myogenic potentials (VEMP) captured in the forearm flexor muscles: a study of its feasibility and reference ranges
CONCLUSIONS: VEMP r ecording from forearm flexors is both feasible and stable, with latency reference ranges between 29.3 and 40.4 ms for P34, and 39.1 and 48.1 ms for N44. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Suicidal behaviors and sedentary lifestyles among adolescents: A cross-sectional epidemiological study in Latin American and Caribbean countries
CONCLUSION: Adolescents of both sexes who reported spending ≥ 3 hours/day in sedentary behaviors were more likely to have some suicidal behaviors than those who spent less time in sedentary behaviors. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Prognostic significance of a normal karyotype in adult patients with BCR-ABL1-positive acute lymphoblastic leukemia in the tyrosine kinase inhibitor era
CONCLUSION: Our results suggest that the sub-classification of an NK could be applied in the prognostic assessments of BCR-ABL1+ ALL. In addition, allo-HSCT should be actively performed to improve prognosis in these patients. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
Residual lesions in patients undergoing microsurgical clipping of cerebral aneurysms in a reference university hospital
CONCLUSION: Incomplete microsurgical aneurysm occlusion is associated with aneurysm size, complexity, and current smoking status. Currently, there is no consensus on postoperative assessment of clipped aneurysms, hindering the correct assessment of treatment outcomes. (Source: Clinics)
Source: Clinics - November 11, 2020 Category: General Medicine Source Type: research
