Outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons shoulder score
Rotator cuff tears are common among the elderly, and studies on the outcomes after rotator cuff repair in the elderly are limited. We carried out this meta-analysis with systematic literature search, aiming to clarify the outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons (ASES) shoulder score. We conducted a literature search through October 2019 in PubMed and EMBASE databases and performed meta-analysis to calculate the summary mean difference comparing the post- and pre-operation ASES scores under both fixed-effect and random-effect models. Among 4978 studies identi...
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
Severe clinical spectrum with high mortality in pediatric patients with COVID-19 and multisystem inflammatory syndrome
CONCLUSIONS: Pediatric patients with laboratory-confirmed COVID-19 with MIS-C had a severe clinical spectrum with a high mortality rate. Our study emphasizes the importance of investigating MIS-C in pediatric patients with COVID-19 presenting with gastrointestinal involvement and hypoxemia. (Source: Clinics)
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
Concordance of Chest CT and Nucleic Acid Testing in Diagnosing Coronavirus Disease Outside its District of Origin (Wuhan, China)
CONCLUSIONS: Patients with positive results on nucleic acid testing may or may not have the abnormal CT manifestations that are frequently found in symptomatic patients with a history of exposure to the district of COVID-19 origin. (Source: Clinics)
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
microRNA-144 functions as a diagnostic and prognostic marker for retinoblastoma
CONCLUSIONS: miR-144 expression was downregulated in serum and tissue samples of RB patients and may function as a diagnostic and prognostic marker for RB. (Source: Clinics)
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
A multidisciplinary approach to prevent and treat pressure sores in proned COVID-19 patients at a quaternary university hospital
Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promises to assist in assessing exposure to and confirming the diagnosis of coronavirus disease 2019 (COVID-19), and to provide a roadmap for reopening countries worldwide. Considering this, a proper understanding of serologic-based diagnostic testing characteristics is critical. The aim of this study was to perform a structured systematic review and meta-analysis to evaluate the diagnostic characteristics of serological-based COVID-19 testing. Electronic searches were performed using Medline (PubMed), EMBASE, and Cochrane Library. Full-text...
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
Diagnostic Characteristics of Serological-Based COVID-19 Testing: A Systematic Review and Meta-Analysis
Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promises to assist in assessing exposure to and confirming the diagnosis of coronavirus disease 2019 (COVID-19), and to provide a roadmap for reopening countries worldwide. Considering this, a proper understanding of serologic-based diagnostic testing characteristics is critical. The aim of this study was to perform a structured systematic review and meta-analysis to evaluate the diagnostic characteristics of serological-based COVID-19 testing. Electronic searches were performed using Medline (PubMed), EMBASE, and Cochrane Library. Full-text...
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
SELAdb: A database of exonic variants in a Brazilian population referred to a quaternary medical center in São Paulo
CONCLUSIONS: Currently, our database comprises a final cohort of 523 unrelated individuals, including patients or fa mily members managed by different clinics of HCFMUSP. We compared SELAdb with other publicly available genomic databases and demonstrated that this population is very heterogeneous, largely resembling Latin American individuals of mixed origin, rather than individuals of pure European ancestry. Inte restingly, exclusively through SELAdb, we identified a spectrum of known and potentially novel pathogenic variants in genes associated with highly penetrant Mendelian disorders, illustrating that pathogenic varia...
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
Survival prognosis of newborns from an intensive care unit through the SNAP-PE II risk score
CONCLUSION: The SNAP-PE II was a beneficial indicator of neonatal mortality. The prevention of prematurity and hypothermia by improving maternity care and newborn care can decisively influence neonatal mortality. (Source: Clinics)
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
Effect of body mass index and rocuronium on serum tryptase concentration during volatile general anesthesia: an observational study
CONCLUSION: Excess weight and obesity predispose to higher preoperative serum tryptase values. Postoperative STC is not linked to rocuronium doses. BMI is the main determinant factor of STC during combined volatile general anesthesia. (Source: Clinics)
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
Prevalence and factors associated with arterial hypertension in a Brazilian rural working population
CONCLUSION: The highest prevalence of hypertension was observed in men, with elevated blood pressure being strongly associated with social and economic factors. In women, the association with the classic factors (age, increase in abdominal adiposity, and low schooling) was stronger. In addition, most hypertensive patients are not adequately diagnosed or treated. (Source: Clinics)
Source: Clinics - August 13, 2020 Category: General Medicine Source Type: research
Laparoscopic surgery and coronavirus disease: What do we know now?
Questions regarding the transmissibility of the novel coronavirus disease (COVID-19) remain unanswered. It is known that the transmission of the severe acute respiratory syndrome coronavirus (SARS-CoV) occurs predominantly through droplets and contact. However, aerosols can be generated in some situations, such as orotracheal intubation, ventilation, and the use of electric or ultrasonic scalpels, and can therefore potentially contaminate the care team if adequate protection is not used. It is therefore necessary to assess issues of transmissibility of COVID-19 during surgery in infected patients. This review gathers the r...
Source: Clinics - August 4, 2020 Category: General Medicine Source Type: research
Impact of microablative fractional radiofrequency on the vaginal health, microbiota, and cellularity of postmenopausal women
CONCLUSION: MAFRF treatment is well tolerated and leads to improvement in the vaginal microenvironment. (Source: Clinics)
Source: Clinics - August 4, 2020 Category: General Medicine Source Type: research
Frailty prevalence and related factors in older adults from southern Brazil: A cross-sectional observational study
CONCLUSIONS: The prevalence of frailty was more pronounced in female than in male individuals, mainly because of a decline in force. Prefrailty was 4 times more prevalent than frailty, and the presence of health problems and reduced functional capacity increased the chances of being prefrail and frail. (Source: Clinics)
Source: Clinics - August 4, 2020 Category: General Medicine Source Type: research
Cross-cultural validation of the FACE-Q Satisfaction with Facial Appearance Overall Scale (FACE-Q SFAOS) in Brazilian rhytidoplasty patients
CONCLUSION: The FACE-Q SFAOS was adapted to the cultural context of Brazilian rhytidoplasty patients and was reproducible, and the scale exhibited face, content and construct validity. (Source: Clinics)
Source: Clinics - August 4, 2020 Category: General Medicine Source Type: research
Use of telemedicine to combat the COVID-19 pandemic in Brazil
(Source: Clinics)
Source: Clinics - August 4, 2020 Category: General Medicine Source Type: research
