Interaction between cognitive status, fear of falling, and balance in elderly persons
CONCLUSION: Elderly persons with cognitive decline have lower balance, greater fear of falling, and greater recurrence of falls. (Source: Clinics)
Source: Clinics - October 26, 2020 Category: General Medicine Source Type: research
Erratum for: Cross-cultural validation of the FACE-Q Satisfaction with Facial Appearance Overall Scale (FACE-Q SFAOS) in Brazilian rhytidoplasty patients
Conclusions: Ultrasound echotexture may detect chronic sialadenitis secondary to salivary radioiodine therapy. (Source: Clinics)
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Ultrasonography Echotexture as a surrogate for Sialadenitis secondary to 131I Radioiodine Therapy for differentiated Thyroid Cancer: a review and metaanalysis
Conclusions: Ultrasound echotexture may detect chronic sialadenitis secondary to salivary radioiodine therapy. (Source: Clinics)
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Serum interleukin-6 level is correlated with the disease activity of systemic lupus erythematosus: a meta-analysis
This study suggested that serum IL-6 levels were higher in patients with SLE than in healthy controls, and they were positively correlated with disease activity when Systemic Lupus Erythematosus Disease Activity Index>4 was defined as active SLE. More homogeneous studies with large sample sizes are warranted to confirm our findings due to several limitations in our meta-analysis. (Source: Clinics)
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Endobronchial ultrasound-guided transbronchial needle aspiration combined with either endoscopic ultrasound-guided fine-needle aspiration or endoscopic ultrasound using the EBUS scope-guided fine-needle aspiration for diagnosing and staging mediastinal diseases: a systematic review and meta-analysis
The present systematic review and meta-analysis aimed to evaluate the available evidence base on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with either endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or endoscopic ultrasound using the EBUS scope-guided fine-needle aspiration (EUS-B-FNA) for diagnosing and staging mediastinal diseases. PubMed, Web of Science, and Embase were searched to identify suitable studies up to June 30, 2019. Two investigators independently reviewed articles and extracted relevant data. Data were pooled using random effect models to calculate d...
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Real-World Molecular Testing and Treatment Patterns in Brazilian Patients with Newly Diagnosed Locally Advanced or Metastatic NSCLC
Conclusion: Our findings provide relevant information for prescribers and policy decision-makers by highlighting the unmet needs of patients and the importance of molecular testing in newly diagnosed locally advanced or metastatic lung adenocarcinoma. We also highlight the respective EGFR-tyrosine kinase inhibitor treatment when the result is positive and the areas in which further efforts are required to grant access to effective treatment. (Source: Clinics)
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Diagnostic value of volumetric capnography in patients with chronic cough variant asthma
CONCLUSION: Patients with cough variant asthma exhibit distinct VCap responses for dead space parameters upon challenge with histamine in comparison to patients with chronic cough. VCap parameters like phase III slope and phase III/phase II slope ratio could be used to aid the diagnosis of cough variant asthma. (Source: Clinics)
Source: Clinics - October 19, 2020 Category: General Medicine Source Type: research
Sepsis and cirrhosis in growing animals: description of a new experimental model and its pathological and immunological reliability
CONCLUSION: The model is feasible and may be utilized in studies on liver cirrhosis and infection in growing animals. (Source: Clinics)
Source: Clinics - September 28, 2020 Category: General Medicine Source Type: research
Unexpectedly High Prevalence of Low Alpha-Galactosidase A Enzyme Activity in Patients with Focal Segmental Glomerulosclerosis
CONCLUSIONS: We found that α GAL activity in patients with FSGS is lower than that in patients undergoing HD. The low enzyme activity in patients with FSGS may be explained by considering the similar pathogenesis of FSGS and FD, which may also lead to sphingolipid deposition and podocyte injury. (Source: Clinics)
Source: Clinics - September 28, 2020 Category: General Medicine Source Type: research
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells
CONCLUSION: Ketamine reduces hypoxia-induced p66Shc expression and attenuates ROS accumulation via upregulating sirt1 in HUVECs, thus attenuating hypoxia-induced endothelial cell inflammation and apoptosis. (Source: Clinics)
Source: Clinics - September 11, 2020 Category: General Medicine Source Type: research
Comparative tomographic study of the iliac screw and the S2-alar-iliac screw in children
CONCLUSIONS: Through CT, the S2AI screw trajectory was observed to have a greater bone thickness and skin distance than the IS. There was a linear correlation between age and screw length for both techniques. A similar relationship was observed between skin distance and age for the S2AI screw technique. In children, the S2AI screw technique presents advantages such as greater cutaneous coverage and implant thickness than the IS technique. (Source: Clinics)
Source: Clinics - September 11, 2020 Category: General Medicine Source Type: research
Accuracy of a portable breath meter test for the detection of halitosis in children and adolescents
CONCLUSION: In the present study involving children, who require fast, practical examinations, BA proved to be an auxiliary tool to OT for the detection of halitosis in the practice of pediatric dentistry, demonstrating high sensitivity and specificity. (Source: Clinics)
Source: Clinics - September 11, 2020 Category: General Medicine Source Type: research
Application of acoustic radiation force impulse elastography combined with serum markers in Child-Pugh grading
CONCLUSIONS: The ARFI value has a strong correlation with the CP class. Therefore, ARFI elastography complements CP class in the assessment of the hepatic functional reserve in patients with CHB-related cirrhosis. (Source: Clinics)
Source: Clinics - September 11, 2020 Category: General Medicine Source Type: research
Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide
CONCLUSION: The median OS of Brazilian patients with GBM treated with RT and TMZ was satisfactory. Although TMZ therapy has become the standard of care for patients with newly diagnosed GBM, the recurrence rate is extremely high. Metronomic TMZ as salvage treatment improved survival in these patients. (Source: Clinics)
Source: Clinics - September 11, 2020 Category: General Medicine Source Type: research
Erratum for: Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience
The aim of this study was to evaluate whether there is a relationship between bleeding response and radiotherapy dose to palliate patients with local recurrence or progression of gastric cancer (GC). To this end, we conducted a systematic review and meta-analysis of observational studies that evaluated the bleeding response in patients with GC with local recurrence or progression. A meta-regression analysis between biological effective dose (BED) and bleeding response was performed, as was subgroup analysis to evaluate the outcome by BED level and radiotherapy (RT) technique. A p-value<0.05 was considered significant. T...
Source: Clinics - September 2, 2020 Category: General Medicine Source Type: research
