Management of Hepatocellular Carcinoma during the COVID-19 Pandemic - São Paulo Clínicas Liver Cancer Group Multidisciplinary Consensus Statement
More than 18 million people in 188 countries have been diagnosed as having coronavirus disease (COVID-19), and COVID-19 has been responsible for more than 600,000 deaths worldwide. Brazil is now the second most affected country globally. Faced with this scenario, various public health measures and changes in the daily routines of hospitals were implemented to stop the pandemic. Patients with hepatocellular carcinoma (HCC) are at an increased risk for severe COVID-19 as they present with two major diseases: cancer and concomitant chronic liver disease. The COVID-19 pandemic can significantly impact the management of HCC pat...
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Is it possible to reverse frailty in patients with chronic obstructive pulmonary disease?
In recent years, frailty has attracted increasing attention from clinicians and health care workers. The influence of frailty on the elderly, especially those with chronic diseases of the respiratory system, is highly significant. Frailty is particularly more common in patients with chronic obstructive pulmonary disease (COPD). Frailty and COPD share many risk factors and pathophysiological mechanisms. As a comprehensive interventional method for chronic respiratory diseases, pulmonary rehabilitation is an important basic measure for the management of patients with COPD. Frailty in these patients can be reversed using pulm...
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Gastrointestinal Manifestations and Associated Health Outcomes of COVID-19: A Brazilian Experience From the Largest South American Public Hospital
CONCLUSION: Based upon this Brazilian study, gastrointestinal manifestations of COVID-19 are common but do not appear to impact clinically relevant hospitalization outcomes including the need for ICU admission, mechanical ventilation, or mortality. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Suicidal behaviors and sedentary lifestyles among adolescents: A cross-sectional epidemiological study in Latin American and Caribbean countries
CONCLUSION: Adolescents of both sexes who reported spending ≥ 3 hours/day in sedentary behaviors were more likely to have some suicidal behaviors than those who spent less time in sedentary behaviors. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Residual lesions in patients undergoing microsurgical clipping of cerebral aneurysms in a reference university hospital
CONCLUSION: Incomplete microsurgical aneurysm occlusion is associated with aneurysm size, complexity, and current smoking status. Currently, there is no consensus on postoperative assessment of clipped aneurysms, hindering the correct assessment of treatment outcomes. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Multiprofessional care promotes of quality of life in pregnant women with preeclampsia: a cross-sectional study
CONCLUSION: There was no difference in quality of life between the groups stu died, a result possibly due to the fact that women with PE were hospitalized and received multiprofessional care. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Impact of Pediatric Hematopoietic Stem-Cell Transplantation on Craniofacial Growth
CONCLUSIONS: Pediatric HSCT has decreased vertical craniofacial growth compared to their matched controls. There might be an association between reduced craniofacial vertical growth and reduced estature growth. Further studies to quantitatively investigate the impact of different myeloablative regimens in craniofacial skeletal growth and development. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Ankylosing spondylitis and psoriatic arthritis: revisiting screening of latent tuberculosis infection and its follow-up during anti-tumor necrosis factor therapy in an endemic area
CONCLUSION: Known re-exposure is the most critical factor for incident TB cases in spondyloarthritis. There are also some distinct features in AS and PsA LTBI screening, considering the higher frequency of LTBI and TST positivities in patients with AS. Annual risk reassessment taking into consideration these peculiar features and including the TST should be recommended for patients in endemic countries. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Optimization of HLA-B*27 ALLELE Genotyping by PCR-SSP
CONCLUSION: The HLA-B*27 genotyping using PCR-SSP, an easy-to-us e, specific, and affordable technique, was optimized for heterozygous samples. This technique may contribute to AS diagnosis. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Pentraxin-2 is Associated with Renal Fibrosis in Patients Undergoing Renal Biopsy
CONCLUSIONS: The results indicated that PTX-2 levels are significantly lower in patients with renal fibrosis than HIs, and declining further in patients with severe fibrosis. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Association Between Work and Common Mental Disorders in School Adolescents: The ERICA Study
CONCLUSION: In the present study, a high number of cases of CMD were observed among the studied adolescents. Female gender and work history in the last year were negatively and independently associated with the presence of CMD. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
The effect of regions-of-interest and elasticity modulus selection on differentiating benign and malignant cervical lymph nodes with shear wave elastography
CONCLUSIONS: This study illustrated the effect of elasticity modulus and ROI selection on the diagnostic performance of SWE on cervical lymphadenopathy. These new findings help guide relevant future studies and clinical applications of this important quantitative imaging modality. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Brainstem Auditory Evoked Potentials in infants aged 1 to 24 months during a hearing health care service
CONCLUSION: There are some differences between the standards in the equipment handbook and those observed in our study. These results will serve as a reference for the standardization of the equipment used in the hearing health care service. (Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Renal involvement in patients with COVID-19
(Source: Clinics)
Source: Clinics - October 30, 2020 Category: General Medicine Source Type: research
Association between matrix metalloproteinase-9 gene polymorphism and breast cancer in Brazilian women
CONCLUSION: In this study, the MMP-9 rs17576 GG polymorphic variant was shown to be significantly associated with breast cancer risk in premenopausal women, while the AG and GG genotypes were associated with increased cancer risk in postmenopausal women. (Source: Clinics)
Source: Clinics - October 26, 2020 Category: General Medicine Source Type: research
