Gentamicin not appropriate as first-line treatment for gonorrhoea, researchers say
Gentamicin is no more effective overall than ceftriaxone as a first-line treatment for gonorrhoea but could be a useful alternative for some patients, researchers have said. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 24, 2019 Category: Drugs & Pharmacology Source Type: research

Oral contraceptives protective against ligament injury in young women
Oral contraceptive pills may be protective against anterior cruciate ligament tears in women, particularly in 15 –19 year olds, a study has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 23, 2019 Category: Drugs & Pharmacology Source Type: research

Cannabis composition alters effects of drug on the brain
Researchers have used functional magnetic resonance imaging  to show how cannabidiol counteracts some of the harmful effects of cannabis on the brain. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 20, 2019 Category: Drugs & Pharmacology Source Type: research

Antibiotics overused in emergency departments for suspected UTI
Over 60% of patients treated for a urinary tract infection lack evidence of the infection, a study carried out in a Birmingham emergency department has found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 16, 2019 Category: Drugs & Pharmacology Source Type: research

Long-term diuretic use may reduce fracture risk in people with Alzheimer ’s disease
Use of thiazide diuretics for three years or more may reduce the risk of low-energy fracture in people with Alzheimer ’s disease, study results have suggested. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 14, 2019 Category: Drugs & Pharmacology Source Type: research

Antibiotic exposure in middle and late adulthood linked to CVD risk
Women exposed to antibiotics in middle or older adulthood have an increased risk of developing cardiovascular disease, a study published in the European Heart Journal suggests. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 10, 2019 Category: Drugs & Pharmacology Source Type: research

Stevens –Johnson syndrome and toxic epidermal necrolysis
Practical guidelines for the treatment and management of Stevens –Johnson syndrome and toxic epidermal necrolysis, rare but life-threatening conditions that are normally caused by drugs or infections. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 10, 2019 Category: Drugs & Pharmacology Source Type: research

Piloting an undergraduate student-led health check service
There is a growing focus on the development of communication and clinical skills during undergraduate pharmacy programmes; this has been demonstrated particularly by the General Pharmaceutical Council ’s recent consultation on initial education and training (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2019 Category: Drugs & Pharmacology Source Type: research

Patterns of medical cannabis use differ between cancer and non-cancer patients
Patients with cancer who use medical cannabis to treat symptoms, such as pain and neuropathy, tend to favour formulations with a higher ratio of the psychoactive component, tetrahydrocannabinol, compared with non-cancer patients. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2019 Category: Drugs & Pharmacology Source Type: research

Substandard and falsified medicines: global and local efforts to address a growing problem
Substandard and falsified medicines pose a risk to public health all around the world. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2019 Category: Drugs & Pharmacology Source Type: research

Triple-combination therapy prevents drug resistance in colorectal cancer cells
Treating colorectal cancer  with a trio of targeted drugs reduces the acquisition of drug resistance, in vitro research published in Oncogene shows. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 7, 2019 Category: Drugs & Pharmacology Source Type: research

Reducing cephalosporin-related supply errors
Cephalosporins are a class of beta-lactam antimicrobials that exert bactericidal effects through disruption of the bacterial cell wall. These broad-spectrum antimicrobials have played a core role in the treatment of severe infections since their launch in the latter half of the 20th century. Early generation cephalosporins provide robust coverage of Gram-positive bacteria, while the newer third- and fourth-generations offer additional Gram-negative coverage, including Pseudomonas ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 2, 2019 Category: Drugs & Pharmacology Source Type: research

‘One-size-fits-all’ treatment targets harm frail older patients with diabetes
HbA1c targets that ignore differences in the physiology of older patients put them at risk of severe hypoglycaemia, harm and death. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 30, 2019 Category: Drugs & Pharmacology Source Type: research

Depression under-recognised in older adults during acute hospital stays
Diagnosis of depression is infrequently recorded on older adults ’ patient notes, a survey of 27 acute hospitals across England has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 18, 2019 Category: Drugs & Pharmacology Source Type: research

Sleeping tablets linked to increased antihypertensive use
Older adults with hypertension who take sleeping tablets are more likely to receive an increased number of antihypertensive medicines over time, study results have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 17, 2019 Category: Drugs & Pharmacology Source Type: research