Can omega-3-rich fish oil supplements reduce allergy risk in infants?
Results from a meta-analysis show that a mother ’s fish oil supplementation during pregnancy may reduce allergy in her children, but the exact benefits of this supplement – and many others – are yet to be determined. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 9, 2018 Category: Drugs & Pharmacology Source Type: research

Understanding cognitive barriers to safer prescribing for frail patients
Deciding to stop medicines that have been prescribed in line with clinical guidelines could be seen as counter-cultural. It goes against the grain for clinicians, and often patients, too. This  Safer Prescribing for Frailty project used an understanding of the cognitive barriers to stopping medicines to enable general practice teams to design, test and embed ways to better meet the medication needs of their frail populations. We took a comprehensive approach to this assessment using ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2018 Category: Drugs & Pharmacology Source Type: research

No significant difference between LAMAs and LABAs in treating persistent asthma, research finds
Data from 15 randomised trials show that while long-acting muscarinic antagonists reduced exacerbation risk by a third, there was no significant improvement compared with long-acting beta-agonists. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2018 Category: Drugs & Pharmacology Source Type: research

Impact of an integrated pharmacy service on hospital admission costs
Abstract The Northumberland Vanguard model of care has pharmacists and technicians working in both hospital and primary care settings, and based in geographical hubs. Each team is part of a wider enhanced care team including community nursing, social care and general practice. The model stratifies patients from low to high need for support with medicines, and a range of clinical pharmacy services are provided to improve patient care and outcomes while reducing ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 8, 2018 Category: Drugs & Pharmacology Source Type: research

ACE inhibitors and beta-blockers reduce risk of cardiotoxicity for some Herceptin patients
Researchers conclude that prophylactic use of lisinopril or carvedilol should be considered in patients who could benefit from anthracycline treatment prior to trastuzumab (Herceptin). (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 4, 2018 Category: Drugs & Pharmacology Source Type: research

Point-of-care C-reactive protein testing in community pharmacy to deliver appropriate interventions in respiratory tract infections
This pilot study sought to evaluate the potential use of point-of-care (POC) C-reactive protein (CRP) testing for respiratory tract infections (RTIs) in a rural community pharmacy in North Staffordshire, UK, in conjunction with local GP practices.  The study found that the use of POC CRP testing in community pharmacies has the potential to reduce the number of GP appointments caused by RTIs and, therefore, may help reduce unnecessary antibiotic prescribing. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 4, 2018 Category: Drugs & Pharmacology Source Type: research

Large study supports use of multimodal pain management after joint replacement
Using data from more than 1.5 million patients who underwent joint replacement surgery, researchers found a stepwise increase in beneficial effects as the number of analgesic modes increased. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - May 2, 2018 Category: Drugs & Pharmacology Source Type: research

Anti-dopaminergic drug could help ease postoperative nausea and vomiting in high-risk patents
Researchers found that 57.7% of patients given amisulpride at induction of inhaled general anaesthetic did not require postoperative rescue medication compared with 46.6% of those assigned to placebo (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 26, 2018 Category: Drugs & Pharmacology Source Type: research

Type 2 diabetes drug may be associated with inflammatory bowel disease
Early results from a trial investigating the link between antidiabetic drugs and autoimmune diseases may have found an association, researchers have revealed (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 23, 2018 Category: Drugs & Pharmacology Source Type: research

Medical cannabis helps manage concurrent cancer-related symptoms
Medical cannabis has been shown to help people living with cancer manage their symptoms, with more than 95% of respondents reporting an improvement. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 23, 2018 Category: Drugs & Pharmacology Source Type: research

Fish oil and probiotic supplements during pregnancy may reduce infant risk of allergic disease
A systematic review and meta-analysis of maternal diets has shown that probiotic and fish oil supplements reduce infant risk of eczema and egg allergy. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 23, 2018 Category: Drugs & Pharmacology Source Type: research

SSRIs quicker than SNRIs at improving anxiety symptoms in young people
Research has shown that selective serotonin reuptake inhibitors used to treat paediatric anxiety disorders offer greater improvements than selective serotonin-norepinephrine reuptake inhibitors. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 17, 2018 Category: Drugs & Pharmacology Source Type: research

Blood test after taking palbociclib could predict response in advanced breast cancer
Research has shown that testing for  PIK3CA levels after taking palbociclib could help predict a progression-free survival, making it the first known biomarker for this therapy. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 17, 2018 Category: Drugs & Pharmacology Source Type: research

Depression in children and young people: identification and management
As one of the most common paediatric psychiatric disorders, pharmacists and healthcare professionals need to be aware of the symptoms of depression and be able to assess children and young people who may be at risk. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 12, 2018 Category: Drugs & Pharmacology Source Type: research

Study results do not support use of hydroxychloroquine in hand osteoarthritis
There is anecdotal evidence that the slow-acting anti-inflammatory treatment hydroxychloroquine, used to treat rheumatoid arthritis, could also be effective in osteoarthritis.   (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - April 6, 2018 Category: Drugs & Pharmacology Source Type: research