PrEP rollout has cut new HIV diagnoses, finds Australian study
Rollout of pre-exposure prophylaxis for HIV has resulted in a rapid decrease of new infections among men who have sex with men, according to data collected in New South Wales, Australia. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 24, 2018 Category: Drugs & Pharmacology Source Type: research

Pharmacists have good understanding of biosimilars but concerns over switching, study results show
UK pharmacists have a high level of understanding of biosimilars but have concerns about the safety and efficacy of switching patients to the drugs, research has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 17, 2018 Category: Drugs & Pharmacology Source Type: research

Semaglutide reduces cardiovascular risk across risk subgroups
GLP-1 agonist semaglutide significantly decreases risk of cardiovascular events and death across different risk groups of patients with type 2 diabetes, secondary analysis of clinical trial data has found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 15, 2018 Category: Drugs & Pharmacology Source Type: research

Lifestyle interventions reduce need for antihypertensive medication in overweight people
Researchers found that assigning overweight patients to the DASH diet and a behavioural weight management programme cut the number of patients eligible for antihypertensive medication (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Reducing suboptimal prescribing of glucagon-like peptide mimetics in type 2 diabetes
In 2016, spend on diabetes prescribing  — and glucagon-like peptide 1 (GLP-1) mimetics, in particular — at NHS Hastings and Rother Clinical Commissioning Group (CCG) and NHS Eastbourne, Hailsham and Seaford CCG was significantly higher than expected, based on national prescribing patterns. There was also significant variation betwee n GP practices. A project was undertaken by the medicines management (MM) team to support primary care diabetes teams to work with patients to optimise prescribing ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Management of acute upper gastrointestinal bleeding
An overview of the assessment process for acute upper gastrointestinal bleeding in the hospital setting and the treatment options available. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 11, 2018 Category: Drugs & Pharmacology Source Type: research

Study results do not support widespread use of statins in old and very old populations
Statins do not prevent the development of atherosclerotic cardiovascular disease (CVD) in people without diabetes aged 75 years and over, according to a study published in the  BMJ. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 10, 2018 Category: Drugs & Pharmacology Source Type: research

Call for submissions on polypharmacy and medicines optimisation
Clinical Pharmacist  today invites article submissions to showcase current and best practice in the area of polypharmacy and medicines optimisation. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 9, 2018 Category: Drugs & Pharmacology Source Type: research

Novel psychoactive substances: understanding the new illegal drug market
Pharmacists should be aware of the expanding illicit drug market and how they can play a role in reducing harm from popular novel psychoactive substances. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 8, 2018 Category: Drugs & Pharmacology Source Type: research

Benzodiazepines linked to risk of Alzheimer ’s disease
Although data showed benzodiazepine and Z drug use was linked to only a 6% increase in the odds of developing Alzheimer ’s disease, researchers say their prescribing should be avoided if possible. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 8, 2018 Category: Drugs & Pharmacology Source Type: research

Palliative management in end-stage liver disease
Early palliative interventions, including reviewing regular medicines and managing  common symptoms, enables patients to remain comfortable during end-of-life care. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 5, 2018 Category: Drugs & Pharmacology Source Type: research

Palliative management in end-stage liver disease
For patients with end-stage liver disease, those receiving early palliative pharmacological interventions report higher quality of life and longer survival. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 5, 2018 Category: Drugs & Pharmacology Source Type: research

Researchers find that e-cigarette fluid becomes more toxic during vaping
Vaping fluid becomes more toxic to cells after it has gone through the vaping process, study results show. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 5, 2018 Category: Drugs & Pharmacology Source Type: research

Antibiotics 'do not cut hospitalisation risk' in children with respiratory infections
Analysis of children presenting in primary care has found that delaying or withholding antibiotics is the most appropriate way of treating suspected respiratory tract infections. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 3, 2018 Category: Drugs & Pharmacology Source Type: research

People with dementia less likely to receive oral anticoagulants despite stroke risk
People with atrial fibrillation who have dementia are less likely to receive oral anticoagulants (OACs) than those without cognitive impairment, research has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - October 1, 2018 Category: Drugs & Pharmacology Source Type: research