Coprolalia Successfully Treated With Aripiprazole in a Child With Tourette Syndrome
No abstract available (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Letters to the Editor Source Type: research
Levetiracetam-Induced Seizure Aggravation in Patients With Focal Cortical Dysplasia
No abstract available (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Letters to the Editor Source Type: research
Beneficial Effect of Betahistine, a Structural Analog of Histamine, in Clozapine-Related Sedation
No abstract available (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Letters to the Editor Source Type: research
Visual Hallucinations Induced by Clarithromycin in a Child: A Case Report and Literature Review
Conclusion
This report highlights neuropsychological adverse effects due to therapeutic doses of clarithromycin therapy as a possible adverse effect in children. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Repetitive Behaviors Treated With N-Acetylcysteine: Case Series
Conclusions
Outcome of our cases demonstrates the efficacy of NAC, which is effective and well tolerated on the treatment of obsessive-compulsive disorder–related disorders. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Catatonia in Adolescence: First Onset Psychosis or Anti-NMDAr Encephalitis?
Catatonia is a rare condition that can occur in developmental disorders, but it is more frequently seen in schizophrenia. Recently, a high prevalence of cerebrospinal fluid abnormalities including the detection of antineuronal autoantibodies has been observed in psychotic patients. Among these autoimmune encephalopathies associated with a psychiatric condition, a great deal of attention has been paid to anti–N-methyl-D-aspartate receptor (NMDAr) encephalitis, which may present, among other things, symptoms such as catatonia, which therefore imposes a differential diagnosis with respect to the early psychosis. The aim of ...
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Memantine Rescues Neurosyphilis-Related Schizophrenic-like Features and Cognitive Deficit
Conclusions
Memantine has an adjunctive effect on neurosyphilis-related neuropsychiatric disorder via modulation of the glutamatergic neurotransmission and microglia-induced neuroinflammation. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Treatment of Sleep Bruxism With a Single Daily Dose of Buspirone in a 7-Year-Old Boy
We present a 7-year-old boy whose sleep bruxism symptoms disappeared with a single daily dose of buspirone treatment in this report. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Long-Term Selegiline Monotherapy for the Treatment of Early Parkinson Disease
Objectives
The aim of this open-label study was to investigate the long-term safety and efficacy of selegiline as monotherapy in Japanese patients with early Parkinson disease (PD).
Methods
We conducted a 56-week prospective study in patients with early PD (N = 134) who had previously completed the randomized, double-blind, placebo-controlled phase III trial of selegiline monotherapy for 12 weeks. In the present study, dosing was titrated from 2.5 to 10 mg/d in increments of 2.5 mg/d for 2 weeks. From the seventh week, the dosage was maintained at 10 mg/d until week 56. The primary outcome was any change in the total ...
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
Curcumin as Add-On to Antipsychotic Treatment in Patients With Chronic Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Study
Conclusions
The promising results of curcumin as an add-on to antipsychotics in the treatment of negative symptoms may open a new and safe therapeutic option for the management of schizophrenia. However, these results should be replicated in further studies.
ClinicalTrials.gov Identifier: NCT 02298985 (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
Subcutaneous Administration of Carbidopa Enhances Oral Levodopa Pharmacokinetics: A Series of Studies Conducted in Pigs, Mice, and Healthy Volunteers
Objectives
Although commercially available levodopa (LD) formulations include carbidopa (CD) or benserazide for gastrointestinal L-aromatic amino acid decarboxylase inhibition, little is known how manipulating CD delivery affects the pharmacokinetics of LD. Our research systematically evaluated the peripheral and central pharmacokinetics of LD during continuous subcutaneous CD delivery.
Methods
We conducted pharmacokinetic experiments in pigs, mice, and humans to characterize effects of continuous subcutaneous CD delivery co-administered with LD as compared with oral LD/CD administration on LD pharmacokinetics. The po...
Source: Clinical Neuropharmacology - July 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
Nortriptyline Abuse: A Case Report and Review of the Literature
This article reviews the prior literature in regard to tricyclic antidepressants and anticholinergics as substances of abuse, the proposed mechanisms of this, and susceptible populations, as well as a case review of a patient who admitted to using nortriptyline for its “buzz.” (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - May 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Cessation of Skin Picking Symptoms With Methylphenidate Treatment in a Child With Comorbid Skin Picking and Attention-Deficit/Hyperactivity Disorder
Skin picking disorder includes behaviors such as picking, scratching, and squeezing of the normal skin in an impulsive, repetitive manner despite the fact that no dermatological condition is detected. Skin picking disorder may also be comorbid in children with attention-deficit/hyperactivity disorder (ADHD) and vice versa. There is a great deal of data regarding the efficacy and safety of methylphenidate (MPH) treatment of ADHD. In this article, we report the cessation of skin picking behaviors in a 10-year-old girl diagnosed as having skin picking disorder and ADHD after modified-release MPH treatment. To our knowledge, t...
Source: Clinical Neuropharmacology - May 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Serotonin Syndrome After an Alcohol Intake in a Patient Treated With Escitalopram and Clomipramine
Conclusions
The present case report suggests that there may be an interaction between alcohol and antidepressants resulting in the serotonin syndrome, and clinicians should be aware of this possibility. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - May 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
Two Cases of De Novo Pathological Gambling Associated With Aripiprazole
Conclusions
In addition to previously recognized risk factors, pathological gambling might occur in young patients whose history did not reveal an addictive tendency while they were sensitive to the pharmacological effect, as well as adverse effects, of psychotropic agents. (Source: Clinical Neuropharmacology)
Source: Clinical Neuropharmacology - May 1, 2019 Category: Neurology Tags: Case Reports Source Type: research
