Clinical Neurology and Neurosurgery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Serum uric acid level is linked to the disease progression rate in male patients with multiple system atrophy
Multiple system atrophy (MSA) is a progressive neurodegenerative disorder that encompasses three syndromes previously considered to be separate disorders: striatonigral degeneration, olivopontocerebellar atrophy, and Shy-Drager syndrome. According to a consensus statement on MSA diagnosis, predominately parkinsonian features are associated with the MSA-P subtype, whereas predominately cerebellar features are associated with the MSA-C subtype [1]. Although the cause of MSA is still unknown, genetic and immunohistological evidence suggests that oxidative stress contributes to MSA pathogenesis [2 –4]. (Source: Clinical Neur...
Source: Clinical Neurology and Neurosurgery - April 3, 2017 Category: Neurosurgery Authors: Jiro Fukae, Shinsuke Fujioka, Shosaburo Yanamoto, Akio Mori, Takahiro Nomi, Taku Hatano, Kousuke Fukuhara, Shinji Ouma, Nobutaka Hattori, Yoshio Tsuboi Tags: Original Articles Source Type: research

Correlation between cervical artery kinking and white matter lesions
White matter lesions (WMLs), commonly called cerebral white matter hyperintensity or leukoaraiosis, are manifestations of cerebral small vessel disease [1]. Furthermore, WMLs include periventricular white matter hyperintensity (PVWMH) and deep white matter hyperintensity (DWMH). The incidence of WMLs in the elderly population is approximately 20%, which is significantly higher than the incidence reported in young people [2]. Moreover, it is widely regarded to be associated with stroke, dementia, and a high risk of death [3]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - April 3, 2017 Category: Neurosurgery Authors: Liang Yin, Qianqian Li, Lina Zhang, Weidong Qian, Xiaolin Liu Source Type: research

Ponticulus posticus: Morphometric analysis and Its anatomical Implications for Occipito-Cervical fusion
PP is a relatively common anatomic variant on the atlas, which is characterized by a bony bridge between the posterior part of the superior articular process and the posterolateral part of the posterior arch of C1. The PP could be a congenital osseous architectural variant and there are several hypotheses for its origin, such as remnants of the pro-atlas, accessory transverse foramen of C1 or ossified primitive ligaments of the posterior atlanto-occipital ligament [1 –4]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - April 2, 2017 Category: Neurosurgery Authors: Ho Jin Lee, Myung Soo Song, Jong Tae Kim, Jung Hee Kim, Jae Taek Hong Source Type: research

Editorial Board
(Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - April 1, 2017 Category: Neurosurgery Source Type: research

Central hypothermia associated with Alexander disease. A case report
Hypothermia is defined by a core body temperature less than 35.0 °C (95.0°F) and can be a life-threatening emergency. Hypothermia can result from a variety of disease and conditions, including environmental exposure, drug intoxication, central nervous system diseases, and metabolic abnormalities such as hypopituitarism, hypoadrenalism, hypothyroidism and hypogl ycemia. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 30, 2017 Category: Neurosurgery Authors: Yuichi Hayashi, Mamoru Nagasawa, Takahiko Asano, Tomokatsu Yoshida, Akio Kimura, Takashi Inuzuka Tags: Case Report Source Type: research

Clinical characteristics and surgical treatment of spinal paraganglioma: a case series of 18 patients
As a kind of extra-adrenal neuroepithelial tumor and also termed as non-adrenal pheochromocytoma, paragangliomas originate from paraganglia cells of sympathetic or parasympathetic autonomic nervous systems, ultimately derived from the neural crest [1,2]. The majority of paragangliomas are benign and non-functional. However, with excessive secretion of catecholamine, they can become functional malignantl. Paragangliomas occur in the jugular glomus and the carotid bodies (80%-90% of cases), and other parts of the body, such as the middle ear, thyroid, gastrointestinal tract and pancreas [3]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Mengchen Yin, Quan Huan, Zhengwang Sun, Shaohui He, Ye Xia, Wen Mo, Junming Ma, Jianru Xiao Source Type: research

Leg Symptoms Associated with Sacroiliac Joint Disorder and Related Pain
Neurogenic or referred symptoms in the leg or legs usually originate from lumbar disorders, and the area and pattern of these symptoms are specific to the underlying pathology and involved neural tissues. For example, lumbar vertebra (L)5 root impairment secondary to lumbar disc herniation typically causes lateral thigh and leg pain on the involved side, particularly after lifting, twisting, or moving a heavy weight [1], while cauda equina syndrome secondary to lumbar spinal canal stenosis commonly results in bilateral posterior leg numbness during walking or standing. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Eiichi Murakami, Toshimi Aizawa, Daisuke Kurosawa, Kyoko Noguchi Source Type: research

Vascular closure devices in stroke patients receiving tissue plasminogen activator: A retrospective analysis from an academic tertiary medical center and a teaching community hospital stroke database
Stroke is the fourth leading cause of death in the United States [1]. Recanalization, or opening, of the blocked artery in ischemic stroke patients can limit the extent of infarction and significantly improve a patient's outcome [2]. In 1995, NINDS tPA (tissue plasminogen activator) trial suggested that tPA administered intravenously within three hours of stroke onset could improve functional outcomes in patients [3]. Since then, acute stroke therapy has been in constant evolution with the universal goals of improving outcomes and reduction in complications. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Mangaladevi S. Patil, Mahesh V. Jayaraman, Sun H. Ahn Source Type: research

No Significant Difference Between Chiari Malformation Type 1.5 and Type I
Chiari malformation (CM), also known as Arnold-Chiari malformation, was first described by the Austrian pathologist Hans Chiari in 1891. It is a congenital malformation and characterized by the downward herniation of the cerebellar tonsils into the spinal canal [1 –4]. According to different morphological changes, Chiari classified these malformations into four types, thus CM type I (CM I), CM type II (CM II), CM type III (CM III), and CM type IV (CM IV) [5–9]. However, for some patients, the morphological changes of the above four entities do not strictl y apply. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Wei Liu, Hongxing Wu, Yalikun Aikebaier, Maoliti Wulabieke, Rexiti Paerhati, Xiaopeng Yang Source Type: research

Elevated hemoglobin is associated with cerebral infarction in Tibetan patients with primary hemorrhagic neurovascular diseases
Primary hemorrhagic neurovascular diseases (PHNVDs) refer to any hemorrhagic events that occur in the central nervous system, mainly including aneurysmal subarachnoid hemorrhage (aSAH), spontaneous intracerebral hemorrhage (sICH) and hemorrhagic arteriovenous malformation (AVM). These events are challenging for neurosurgeons due to their high rates of morbidity and poor prognoses [2,15,19,29,33]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Ruiqi Chen, Anqi Xiao, Lu Ma, Hao Li, Sen Lin, Chao You Source Type: research

Top-100 Cited Articles on Headache Disorders: a Bibliometric analysis
Headache is one of the most common disorders of the nervous system, and it has several subtypes: primary headache such as tension-type headache (TTH), migraine, and cluster headache; secondary headache; and other headaches [1]. Headache has a high prevalence, with worldwide epidemiology studies having found the global prevalence rates of current headache, migraine, and TTH to be 47%, 10%, and 38%, respectively, with corresponding lifetime prevalence rates of 66%, 14%, and 46% [2]. Headache disorders are highly burdensome at both the individual and societal levels, with a substantial penalty in lost production [3], and henc...
Source: Clinical Neurology and Neurosurgery - March 23, 2017 Category: Neurosurgery Authors: Kang Min Park, Bong Soo Park, Sihyung Park, Dae Young Yoon, Jong Seok Bae Source Type: research

CSF lactate alone is not a reliable indicator of bacterial ventriculitis in patients with ventriculostomies
A febrile patient with a ventriculostomy presents a diagnostic challenge. Hyperthermia and meningeal signs are common in patients who have undergone neurosurgery or are recovering from intracerebral or subarachnoid hemorrhages, and are not necessarily indicative of cerebrospinal fluid (CSF) infection. Furthermore, presence of blood and inflammation make CSF analysis difficult, and use of periprocedural antibiotics or antibiotics for prevention of ventriculostomy-related infection can affect the reliability of initial gram stain. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 22, 2017 Category: Neurosurgery Authors: Emily Hill, Thomas P. Bleck, Kamaljit Singh, Bichun Ouyang, Katharina M. Busl Source Type: research

Anxiety in the preoperative phase of awake brain tumor surgery
Intraoperative stimulation brain mapping helps maximize the extent of resection and reduce the surgical risk present and is performed increasingly in patients with brain tumors located in an eloquent area [1,2]. An important part of the pre-operative phase of awake craniotomies is the neuropsychological work-up, which evaluates the baseline performance of the patient especially at tests that will be performed during the surgery and patients ’ suitability for the procedure. Anxiety is an important factor herein for several reasons. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 22, 2017 Category: Neurosurgery Authors: Carla Ruis, Irene Huenges Wajer, Pierre Robe, Martine van Zandvoort Source Type: research

CSF lactate is not a reliable indicator of bacterial ventriculitis in patients with ventriculostomies
A febrile patient with a ventriculostomy presents a diagnostic challenge. Hyperthermia and meningeal signs are common in patients who have undergone neurosurgery or are recovering from intracerebral or subarachnoid hemorrhages, and are not necessarily indicative of cerebrospinal fluid (CSF) infection. Furthermore, presence of blood and inflammation make CSF analysis difficult, and use of periprocedural antibiotics or antibiotics for prevention of ventriculostomy-related infection can affect the reliability of initial gram stain. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 22, 2017 Category: Neurosurgery Authors: Emily Hill, Thomas P. Bleck, Kamaljit Singh, Bichun Ouyang, Katharina M. Busl Source Type: research

Variation in selection criteria and approaches to surgery for Lumbar Spinal Stenosis among patients treated in Boston and Norway
There are no uniform guidelines regarding when to operate or the ideal surgical intervention in Lumbar Spinal Stenosis (LSS). Understanding the presence of practice-based variation between different localities is critical. We sought to compare patient-reported pre-operative pain, disability, and health-related quality of life as indications for surgery between Boston and Norway, and the use of decompression alone vs. decompression and arthrodesis. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - March 20, 2017 Category: Neurosurgery Authors: Greger L ønne, Andrew J. Schoenfeld, Thomas D. Cha, Øystein P. Nygaard, John Anker H. Zwart, Tore Solberg Source Type: research