Clinical Neurology and Neurosurgery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Post-operative unilateral internuclear ophthalmoplegia following basilar pneumocephalus after resection of C1 intradural extramedullary tumor
Internuclear ophthalmoplegia (INO), a gaze abnormality causing weak adduction of the affected eye and abduction nystagmus of the contralateral eye, results from damage of the medial longitudinal fasciculus (MLF) in the dorsomedial brainstem tegmentum of either the pons or the midbrain. When pneumocephalus, which is air or gas within the cranial cavity, becomes symptomatic then it is called tension pneumocephalus. Tension pneumocephalus affecting the brainstem has been known to various ocular symptoms such as 3rd nerve palsy [1] and pupillary changes [2]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 16, 2017 Category: Neurosurgery Authors: Deb Kumar Mojumder, Jason Choi, Ben Zion Roitberg Tags: Case Report Source Type: research

Effective and Safe Mannitol Administration in Patients Undergoing Supratentorial Tumor Surgery: A Prospective, Randomized and Double Blind Study
The management of increased intracranial pressure (ICP) and brain relaxation are the main factors determining the clinical and surgical outcomes in neurosurgery [1]. Although the safe and effective dose of mannitol, the duration of administration and its use in combination with loop diuretics, such as furosemide, are still matters of debate, mannitol remains a common treatment approach for brain relaxation [2]. Distal loop diuretics promote further fluid excretion and sustain the osmotic effect initiated by mannitol. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 15, 2017 Category: Neurosurgery Authors: Eren Akcil, Ozlem Korkmaz Dilmen, Esra Sultan Karabulut, Serdar Selcuk Koksal, Fatis Altindas, Yusuf Tunali Source Type: research

Atypical presentation and outcome of cervicogenic headache in patients with cervical degenerative disease: A single-center experience
Headache is a major health concern and the most prevalent (66%) pain disorder in the worldwide population [1]. It interferes with quality of life, reduces work productivity and increases health care costs [2]. The International Headache Society has classified and sub-classified headaches based on their characteristics and sources. Thirty-eight percent of all headaches are tension headaches, the most common type. Ten percent of headaches are migraines; three percent are chronic daily headaches; and 2.5 –4.1% are CGH [3]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 13, 2017 Category: Neurosurgery Authors: Shyamal C. Bir, Anil Nanda, Devi Prasad Patra, Tanmoy Kumar Maiti, Cesar Liendo, Minagar Alireza, Oleg Y. Chernyshev Source Type: research

The association of arachnoid cysts and focal epilepsy: Hospital based case control study
Intracranial cysts are heterogeneous lesions and common findings in brain Magnetic Resonance Imaging (MRI), with a broad hystopathological spectrum [1]. Two studies discovered that individuals in the general population present with a variety of abnormalities on neuroimaging: Katzman et al. (1999) reported that 18% of healthy asymptomatic subjects demonstrated incidental abnormal findings, including very rare cysts ie. nasopharygeal cysts (0.1%), choroid and pineal cysts (0.2%), and arachnoid cysts (0.3%) [2], and Vernooij et al. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 12, 2017 Category: Neurosurgery Authors: Ivan Nikoli ć, Aleksandar Ristić, Nikola Vojvodić, Vladimir Baščarević, Andrej Ilanković, Ivana Berisavac, Tijana Đukić, Dragoslav Sokić Source Type: research

The interventional effect of new drugs combined with the Stupp protocol on glioblastoma: A network meta-analysis
Glioblastoma (GBM), an invasive solid tumor, is the most common primary tumor of the brain [1,2]. The standard treatment is radiotherapy (RT) plus concomitant and adjuvant therapy, with six cycles of temozolomide (TMZ) following surgical removal of the maximum safe scope, which is currently the internationally accepted treatment protocol (also was the Stupp protocol). However, despite the availability of advanced treatment, patients with GBM have a poor prognosis, with average survival of only 14.6 –16 months and a 5-year survival rate of less than 10%, thus representing a significant treatment challenge [3–5]. (Source...
Source: Clinical Neurology and Neurosurgery - May 11, 2017 Category: Neurosurgery Authors: Mei Li, Xiangqi Song, Jun Zhu, Aijun Fu, Jianmin Li, Tong Chen Source Type: research

One-stage posterior grade 4 osteotomy and bone graft fusion at pseudarthrosis for the treatment of kyphotic deformity with Andersson lesions in ankylosing spondylitis
Ankylosing spondylitis (AS) is a chronic inflammatory disease, characterized by ossification of the ligaments of the spinal column, annulus fibrosis, endplates, and apophyseal joints, resulting in the formation of a “bamboo spine” [1–3]. Ankylosis of the spine also causes vertebral osteoporosis and biomechanical alterations [4,5]. Spinal pseudarthrosis is a well-known complication in AS patients [3,6]. This pseudarthrosis often progresses to destructive lesions of the intervertebral disc and vertebral bod y at the site of pseudarthrosis [6,7], known as Andersson lesions (ALs) [3]; ALs lead to persistent back pain, pr...
Source: Clinical Neurology and Neurosurgery - May 11, 2017 Category: Neurosurgery Authors: Tingxian Ling, Bangjian Zhou, Ce Zhu, Xi Yang, Yueming Song, Zhe Qiang, Limin Liu Source Type: research

Editorial Board
(Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Source Type: research

Predictors of poor visual outcome in patients with Idiopathic Intracranial Hypertension (IIH): an ambispective cohort study
Idiopathic Intracranial Hypertension (IIH) is characterized by features of raised intracranial pressure (ICP), causing headache, papilledema and potential visual loss in the absence of a space-occupying lesion or other identifiable cause. Initially described as serous meningitis by Quincke in 1893 [1], IIH still remains a disorder of uncertain pathogenesis. The clinical course is very variable with headache causing long term disability and visual loss being a potential threat. Prompt diagnosis and treatment are important because permanent visual field loss is common and blindness occurs in 10% of affected individuals [2,3]...
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Authors: Amit Agarwal, Deepti Vibha, Kameshwar Prasad, Rohit Bhatia, Mamta Bhushan Singh, Ajay Garg, Rohit Saxena Source Type: research

Analysis of extracellular brain chemistry during percutaneous dilational tracheostomy: a retrospective study of 19 patients
The use of tracheostomy in critical care patients, requiring long term mechanical ventilation is well established [9,21]. In the treatment of patients with severe acute brain injury (ABI) long-term ventilation is used widely, due to a poor conscious state or for specific neuroprotective effects [16,23]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Authors: Jan K üchler, Jann Wojak, Abdulkareem Abusamha, Claudia Ditz, Volker Martin Tronnier, Jan Gliemroth Source Type: research

CT and MRI-based Door-Needle-Times for acute stroke patients A quasi-randomized clinical trial
The aim of this study was to compare DNT for CT versus MRI-based acute stroke-evaluation. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Authors: Christine Krarup Hansen, Anders Christensen, Helen Rodgers, Inger Havsteen, Christina Kruuse, Janus Nybing, Mari-Anne Kaasb øl, Hanne Christensen Source Type: research

Comparison of the efficacy of fixed-dose enoxaparin and adjusted-dose unfractionated heparin in patients with cerebral venous thrombosis
Cerebral venous thrombosis (CVT) is a potentially fatal disease [1]. The incidence of CVT in Europe and America was estimated to be 3 to 4 patients per million population while the incidence in the Asian population was not well documented [2]. Although there are various precipitating factors that contribute to CVT, different genetic backgrounds lead to a lower incidence of thrombophilia-related CVT in the Asian population than in the Western population [3]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Authors: Pat Korathanakhun, Chusana Petpichetchian, Wongchan Petpichetchian, Pornchai Sathirapanya Tags: Full Length Article Source Type: research

Relevance of non-specific MRI features in multiple system atrophy
Multiple system atrophy (MSA) is a sporadic progressive neurodegenerative disorder characterized by autonomic failure, Parkinsonism (poorly responsive to levodopa), cerebellar ataxia and corticospinal dysfunction [1 –5]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 9, 2017 Category: Neurosurgery Authors: Sunil Pradhan, Ruchika Tandon Source Type: research

Clinical characteristics and PRRT2 gene mutation analysis of sporadic patients with paroxysmal kinesigenic dyskinesia in China
Paroxysmal kinesigenic dyskinesia (PKD) is a rare kind of paroxysmal movement disorders, which is characterized by recurrent brief episodes of dystonia,athetosis,chorea or a combination. And PKD is triggered by initiation of voluntary movements. It mainly affects children. Each occurrence last a few seconds, with recurring at variable frequency, and without any disturbance of consciousness. Severity of attacks diminished with age. PKD response well to anti-epileptic drugs (AEDs) [1,2]. Most of the reported cases of PKD are familial and inherited in an autosomal dominant trait. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 8, 2017 Category: Neurosurgery Authors: Yu Zhang, Lin Li, Wei Chen, Jing Gan, Zhen guo Liu Source Type: research

Comparison of electromagnetic neuronavigation system and free-hand method for ventricular catheter placement in internal shunt
Ventriculoperitoneal (VP) shunt is a frequent surgery mainly characterized by a high risk of re-intervention reaching more than 50% [1] in some series. The most frequent cause for re-intervention is obstruction of the proximal catheter, followed by infection and disconnection [2]. It is commonly admitted that the position of the proximal catheter determines the rate of success of the procedure [1]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 8, 2017 Category: Neurosurgery Authors: Vianney Gilard, Nicolas Magne, Emmanuel Gerardin, Sophie Curey, Val érie Pelletier, Pierre Hannequin, Stéphane Derrey Source Type: research

Eagle Syndrome: A Comprehensive Review
Eagle Syndrome is a rare and poorly understood clinical condition that presents with a myriad of symptoms that typically include pain in the anterolateral neck. These symptoms are associated with an abnormal styloid process. Fig. 1 shows a schematic of normal anatomy along with an elongated styloid process. Eagle initially described a pain syndrome associated with an elongated styloid process in 1937 as “stylalgia” [1]. Eagle subsequently expanded on his initial descriptions [2–6]. Historically stylohyoid pain syndromes have been delineated based upon their etiology, i.e. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - May 6, 2017 Category: Neurosurgery Authors: Arvind Badhey, Ameya Jategaonkar, Alexander Joseph Anglin Kovacs, Sameep Kadakia, Peter Paul De Deyn, Yadranko Ducic, Stimson Schantz, Edward Shin Tags: Review Article Source Type: research