Surgical management of arrested hydrocephalus: case report, literature review, and 18-month follow-up
Adult hydrocephalus is a heterogeneous clinical entity that likely encompasses multiple syndromes with varied etiologies. This is reflected in the literature, where various groups have referred to the condition as “arrested hydrocephalus,” “asymptomatic hydrocephalus,” “occult hydrocephalus,” “compensated hydrocephalus,” and more recently, “long-standing overt ventriculomegaly of adulthood (LOVA),” or “late-onset idiopathic aqueductal stenosis (LIAS)” [1–5]. These diagnoses share a r adiographic finding of stable, enlarged ventricles and a clinical history of normal development and neurologic func...
Source: Clinical Neurology and Neurosurgery - October 26, 2016 Category: Neurosurgery Authors: Jennifer Hong, Benjamin G. Barrena, S. Scott Lollis, David F. Bauer Source Type: research

Evaluation of histopathological changes in the microstructure at the center and periphery of glioma tumors using diffusional kurtosis imaging
Gliomas are the most common intrinsic brain tumor of the central nervous system. Glioma tissues are inhomogeneous in nature. In the process of malignant transformation, the histopathological characteristics of the tumor will change drastically, mirroring the changes in tumor microstructure [1]. Conventional MR imaging techniques have documented the macrostructural changes in gliomas [2]. However, detection of these changes at the microstructural level is limited using these techniques; for example, during the course of tumor progression gliomas exhibit increased levels of cellularity, micronecrosis and vascular hyperplasia...
Source: Clinical Neurology and Neurosurgery - October 26, 2016 Category: Neurosurgery Authors: Fuyan Li, Wenqi Shi, Dawei Wang, Yanjie Xu, Hongxia Li, Jingzhen He, Qingshi Zeng Tags: Full length article Source Type: research

Multiple whistling seizures in temporal lobe epilepsy: a case report and review of the literature
We report a case of multiple focal dyscognitive seizures with prominent whistling recorded on video-telemetry in a patient with temporal lobe epilepsy and cognitive impairment. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 24, 2016 Category: Neurosurgery Authors: Andrew Lawley, Haseeb A. Khan, Vishwajit Hegde Tags: Case Report Source Type: research

C2 dumbbell-shaped peripheral nerve sheath tumors: surgical management and relationship with venous structures
Upper cervical nerve peripheral nerve sheath tumors (PNSTs) include schwannomas and neurofibromas and arise mainly from the second cervical (C2) root [1,2]. C2 PNSTs can grow to a large size while remaining asymptomatic and extend via the intervertebral foramina to achieve a dumbbell shape [1,2]. C2 PNSTs have specific characteristics, such as multiplicity, a dumbbell shape, a relationship with the vertebral artery (VA), and particular associated surgical problems [1 –3]. The VA can be displaced and compressed by the extradural portion of a C2 PNST, and some authors have suggested that the VA is the main problem for tota...
Source: Clinical Neurology and Neurosurgery - October 23, 2016 Category: Neurosurgery Authors: Zuowei Wang, Xingwen Wang, Hao Wu, Zan Chen, Qingguo Yuan, Fengzeng Jian Source Type: research

Impact of Timing of Radiotherapy in Patients with Newly Diagnosed Glioblastoma
Glioblastoma (GBM) is an aggressive and rapidly progressive brain tumor. Several prior series have demonstrated a survival advantage associated with greater extent of surgical resection [1,2]. Due to the benefit of the reduction of tumor burden and the concern for rapid recurrence of these aggressive tumors, a bias amongst practitioners has existed for minimizing the time delay between surgery and the commencement of radiotherapy (RT). It has been assumed that starting RT prior to tumor repopulation may lead to an advantage for patients with greater extent of resection. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 21, 2016 Category: Neurosurgery Authors: David M. Randolph, Emory R. McTyre, Anna K. Paulsson, Jordan A. Holmes, William H. Hinson, Glenn J. Lesser, Roy Strowd, Hui-Wen Lo, Adrian W. Laxton, Stephen B. Tatter, Waldemar Debinski, Michael D. Chan Source Type: research

Profile of autonomic dysfunctions in patients with primary brain tumor and possible autoimmunity
Cerebral lesion due to different neurological conditions, e.g. stroke, head injury, inflammation, etc., with high intracranial pressure, could be complicated by autonomic dysfunction. Autonomic dysregulation was reported in the literature as a sympathetic hyperactivity, in some cases, mostly after brain injury, as a severe “paroxysmal sympathetic storm”. Dysfunction of autonomic centers in diencephalon, insular cortex, or even anterior cingulated, loss of the cortical or subcortical control, activation or dysinhibition of sympathoexcitatory regions are possible in the pathogenesis of dysautonomia [1–5]. (Source: Clin...
Source: Clinical Neurology and Neurosurgery - October 21, 2016 Category: Neurosurgery Authors: Magdalena Koszewicz, Slawomir Michalak, Malgorzata Bilinska, Slawomir Budrewicz, Mikolaj Zaborowski, Krzysztof Slotwinski, Ryszard Podemski, Maria Ejma Source Type: research

Significance of the prognostic nutritional index in patients with glioblastoma: a retrospective study
Glioblastoma multiforme (GBM) is the most common malignant glioma. Moreover, the tumors are highly invasive and likely to recur [1]. The clinical outcomes are various even if patients receive combined radiotherapy and temozolomide(TMZ) treatment following tumor resection [2], which indicates that potential prognostic factors may influence the overall survival(OS). Thus, identifying the variables associated with prognosis of patients with GBM can guide individual treatment. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 21, 2016 Category: Neurosurgery Authors: Xing-wang Zhou, Hui Dong, Yuan Yang, Jiewen Luo, Xiang Wang, Yan-hui Liu, Qing Mao Tags: Full Length Article Source Type: research

Diabetes Mellitus in Classical Trigeminal Neuralgia: a predisposing factor for its development
Trigeminal Neuralgia (TN) is defined as a sudden, usually unilateral, severe, brief, stabbing, recurrent episodes of pain in the distribution of one or more branches of the trigeminal nerve. Most of the cases are Classic Trigeminal Neuralgia (CTN) without an established etiology [1]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 21, 2016 Category: Neurosurgery Authors: Zhenq Xu, Ping Zhang, Li Long, Huiy He, Jianch Zhang, Shup Sun Source Type: research

Pisa syndrome and scoliosis in Parkinson ’s disease
I read with interest the letter of Cervantes-Arriaga and colleagues [1] describing the frequency of abnormal postures and striatal deformities in a sample of subjects with Parkinson ’s disease (PD). (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 19, 2016 Category: Neurosurgery Authors: Paolo Solla Source Type: research

Prevention of infection by antibiotic-impregnated shunts after pediatric hydrocephalus treatment: A single center, retrospective study in China
Note: The contents of the manuscript have not been previously presented or published. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 16, 2016 Category: Neurosurgery Authors: Bo Yang, Yunhai Song, Pingping Gao, Nan Bao Source Type: research

Management of postoperative pain after Lumbar surgery —pregabalin for one day and 14 days—a randomized, triple-blinded, placebo-controlled study
Low back pain (LBP) is considered as vast economic burden for health care systems. The estimated incidence for the general population is about 60 –80% [1,2]. Despite the progress in understanding acute pain physiology during recent decades, eighty percent of patients still suffer from post-operative discomfort [3]. The pain depends on how many Vertebrae has been operated and the invasiveness of our approach [4]. Unsuccessful control of this pain can cause muscle wasting, depression, sensitization of the nervous system, depression, hyper reactivity of autonomic system and stiffening of the joints [5,6]. (Source: Clinical ...
Source: Clinical Neurology and Neurosurgery - October 15, 2016 Category: Neurosurgery Authors: Mohammad Zarei, Arvin Najafi, Pejman Mansouri, Sadaf Sadeghi-Yazdankhah, Houshang Saberi, Mehran Moradi, Mahmoud Farzan Source Type: research

Management of postoperative pain after Lumbar surgery; pregabalin for one day and 14 days; a randomized, triple-blinded, placebo-controlled study
Low back pain (LBP) is considered as vast economic burden for health care systems. The estimated incidence for the general population is about 60 to 80% [1,2]. Despite the progress in understanding acute pain physiology during recent decades, eighty percent of patients still suffer from post-operative discomfort [3]. The pain depends on how many Vertebrae has been operated and the invasiveness of our approach [4]. Unsuccessful control of this pain can cause muscle wasting, depression, sensitization of the nervous system, depression, hyper reactivity of autonomic system and stiffening of the joints [5,6]. (Source: Clinical ...
Source: Clinical Neurology and Neurosurgery - October 15, 2016 Category: Neurosurgery Authors: Mohammad Zarei, Arvin Najafi, Pejman Mansouri, Sadaf Sadeghi-Yazdankhah, Houshang Saberi, Mehran Moradi, Mahmoud Farzan Source Type: research

Geomagnetic disturbance: a new field in multiple sclerosis research
Dear Editor, (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 14, 2016 Category: Neurosurgery Authors: Seyed Aidin Sajedi, Fahimeh Abdollahi Tags: Letter to the Editor Source Type: research

Bilateral posterior cortical diffusion restriction due to electrocution
Chauhan et al. reported an extremely interesting patient presenting with reversible cortical blindness following electrocution in the subacute period [1]. The patient had admitted with sudden onset headache and bilateral visual blurring which had suddenly developed one week later electrocution. Concurrently performed cranial MRI had showed bilateral cortical diffusion restriction in parieto-occipital regions. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 14, 2016 Category: Neurosurgery Authors: Halil Onder Tags: Correspondence Source Type: research

The incidence of and risk factors for ischemic complications after microsurgical clipping of unruptured middle cerebral artery aneurysms and the efficacy of intraoperative monitoring of somatosensory evoked potentials: A retrospective study
An increasing number of unruptured intracranial aneurysms (UIAs) are now being detected owing to advancements in diagnostic imaging techniques. However, the management of UIAs remains controversial. According to the results of large multicenter studies, such as the International Study of Unruptured Intracranial Aneurysms and International Subarachnoid Aneurysm Trial [1,2], more neurosurgeons are considering endovascular treatment as the first choice of treatment modality for intracranial aneurysms. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 13, 2016 Category: Neurosurgery Authors: Hyoung Soo Byoun, Jae Seung Bang, Chang Wan Oh, O-Ki Kwon, Gyojun Hwang, Jung Ho Han, Tackeun Kim, Si Un Lee, Seong-Rae Jo, Dong-Gun Kim, Kyung Seok Park Source Type: research