Reply to Cohen et al
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Oldenburg, C. E., Bärnighausen, T., Tanser, F., Iwuji, C. C., De Gruttola, V., Seage, G. R., Mimiaga, M. J., Mayer, K. H., Pillay, D., Harling, G. Tags: CORRESPONDENCE Source Type: research

Role of K13 Mutations in Artemisinin-Based Combination Therapy
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Rasmussen, C., Ariey, F., Fairhurst, R. M., Ringwald, P., Menard, D. Tags: CORRESPONDENCE Source Type: research

Antiretroviral Therapy to Prevent HIV Acquisition: Limits of Estimation From a Population Cohort
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Cohen, M., Eshleman, S., McCauley, M., Chen, Y. Tags: CORRESPONDENCE Source Type: research

HIV Medicine Residency Training: Experience From Mississippi
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Brock, J. B., Mena, L. A. Tags: CORRESPONDENCE Source Type: research

Reply to Sullivan
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Bonura, E. M., Ramsey, K., Armstrong, W. S. Tags: CORRESPONDENCE Source Type: research

Declining Interest in Infectious Diseases: An Economic Problem That Requires Economic Solutions
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Sullivan, T. Tags: CORRESPONDENCE Source Type: research

Immediate Antiretroviral Therapy Reduces Risk of Infection-Related Cancer During Early HIV Infection
Conclusions. Immediate cART initiation significantly reduces risk of cancer. Although limited by small sample size, this benefit does not appear to be solely attributable to HIV RNA suppression and may be also mediated by other mechanisms. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Borges, A. H., Neuhaus, J., Babiker, A. G., Henry, K., Jain, M. K., Palfreeman, A., Mugyenyi, P., Domingo, P., Hoffmann, C., Read, T. R. H., Pujari, S., Meulbroek, M., Johnson, M., Wilkin, T., Mitsuyasu, R., for the INSIGHT START Study Group Tags: HIV/AIDS Source Type: research

Suboptimal Adherence to Combination Antiretroviral Therapy Is Associated With Higher Levels of Inflammation Despite HIV Suppression
Conclusions. Higher concentrations of inflammatory biomarkers were observed among HIV RNA–suppressed men who reported <100% cART adherence than among more adherent men. Residual HIV replication (ie, below the limit of detection), more likely among men with suboptimal adherence, is a plausible mechanism. Whether improving cART adherence could affect residual inflammation and associated morbidity and mortality rates should be investigated. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Castillo-Mancilla, J. R., Brown, T. T., Erlandson, K. M., Palella, F. J., Gardner, E. M., Macatangay, B. J. C., Breen, E. C., Jacobson, L. P., Anderson, P. L., Wada, N. I. Tags: HIV/AIDS Source Type: research

Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults
Conclusions. In this cross-sectional analysis, LTI was associated with NCI, especially in those with higher CD4+ T-cell counts. Longitudinal studies to investigate the role of neuroinflammation and neuronal injury in LTI patients with NCI and trials of anti-Toxoplasma therapy should be pursued. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Bharti, A. R., McCutchan, A., Deutsch, R., Smith, D. M., Ellis, R. J., Cherner, M., Woods, S. P., Heaton, R. K., Grant, I., Letendre, S. L. Tags: HIV/AIDS Source Type: research

Suboptimal Viral Suppression Rates Among HIV-Infected Children in Low- and Middle-Income Countries: A Meta-analysis
Conclusions. Viral suppression rates among children on ART in LMICs were low and considerably poorer than those previously found in adults in LMICs and children in high-income countries. Little progress has been made in improving viral suppression rates over the past years. Without increased efforts to improve pediatric HIV treatment, the 90-90-90 goal for children in LMIC will not be reached. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Boerma, R. S., Boender, T. S., Bussink, A. P., Calis, J. C. J., Bertagnolio, S., Rinke de Wit, T. F., Boele van Hensbroek, M., Sigaloff, K. C. E. Tags: HIV/AIDS Source Type: research

Measuring Appropriate Antimicrobial Use: Attempts at Opening the Black Box
Indiscriminate antimicrobial use has plagued medicine since antibiotics were first introduced into clinical practice >70 years ago. Infectious diseases physicians and public health officials have advocated for preservation of these life-saving drugs for many years. With rising burden of antimicrobial-resistant organisms and Clostridium difficile infections, halting unnecessary antimicrobial use has become one of the largest public health concerns of our time. Inappropriate antimicrobial use has been quantified in various settings using numerous definitions; however, no established reference standard exists. With mountin...
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Spivak, E. S., Cosgrove, S. E., Srinivasan, A. Tags: QUALITY IMPROVEMENT Source Type: research

Trends of Media Coverage on Human Papillomavirus Vaccination in Japanese Newspapers
A sensational newspaper article concerning a possible adverse reaction to the human papillomavirus (HPV) vaccine was published in March 2013 in Japan. In June 2013, the Japanese government suspended their proactive recommendation for vaccination, despite the lack of proof for a causal relationship. We searched Nikkei Telecom 21, the largest newspaper database in Japan, for articles published from January 2011 to December 2015 to evaluate the characteristics of newspaper publications about human papillomavirus vaccination. We identified 1138 HPV vaccine–related articles. Compared with those published before March 2013...
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Tsuda, K., Yamamoto, K., Leppold, C., Tanimoto, T., Kusumi, E., Komatsu, T., Kami, M. Tags: VACCINES Source Type: research

Identification of 12 Cases of Acute Measles Encephalitis Without Rash
Twelve cases of acute measles encephalitis without rash were identified from October 2011 to July 2013 in Changsha city, China; 5 were found to be genotype H1 and 2 were B3. Our data suggest that screening for measles virus is necessary in children with viral encephalitis, to eliminate the disease. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Zeng, S.-Z., Zhang, B., Zhang, Y., Xie, L.-Y., Xiong, J., Yu, T., Xie, Z.-p., Gao, H.-c., Duan, Z.-J. Tags: BRIEF REPORTS Source Type: research

Diagnosis and Clinical Management of Schistosoma haematobium-Schistosoma bovis Hybrid Infection in a Cluster of Travelers Returning From Mali
Ten Belgian travelers returned from Mali with a Schistosoma haematobium–Schistosoma bovis hybrid infection, confirmed by DNA sequencing from eggs. Clinical symptoms and laboratory findings resembled those of classic acute schistosomiasis, but the detected eggs were morphologically unusual. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Soentjens, P., Cnops, L., Huyse, T., Yansouni, C., De Vos, D., Bottieau, E., Clerinx, J., Van Esbroeck, M. Tags: BRIEF REPORTS Source Type: research

Fetal Infection by Zika Virus in the Third Trimester: Report of 2 Cases
We describe 2 cases of ZIKV infection in women in their 36th week of pregnancy whose fetuses had preserved head circumference at birth and findings of subependymal cysts and lenticulostriate vasculopathy in postnatal imaging. These represent the first signs of congenital brain injury acquired due to ZIKV in the third trimester. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Authors: Soares de Souza, A., Moraes Dias, C., Braga, F. D. C. B., Terzian, A. C. B., Estofolete, C. F., Oliani, A. H., Oliveira, G. H., Brandao de Mattos, C. C., de Mattos, L. C., Nogueira, M. L., Vaz-Oliani, D. C. M. Tags: BRIEF REPORTS Source Type: research