Cover
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Cell-Mediated Immunity in HIV-Infected Males With Human Papillomavirus-Related Anal Dysplastic Lesions
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Tincati, C., Rainone, V., Comi, L., Pandolfo, A., Barco, A., Bellistri, G. M., Rovati, M., Monforte, A. d., Trabattoni, D., Marchetti, G. Tags: CORRESPONDENCE Source Type: research

Treatment of Hospital or Ventilator-Associated Pneumonia Due to Carbapenem-Resistant Enterobacteriaceae: Leveraging Molecular Resistance Testing and Combination Therapy to Improve Outcomes
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Gomez, C. A., Deresinski, S. Tags: CORRESPONDENCE Source Type: research

Coexistence of MCR-1 and NDM-1 in Clinical Escherichia coli Isolates
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Zheng, B., Dong, H., Xu, H., Lv, J., Zhang, J., Jiang, X., Du, Y., Xiao, Y., Li, L. Tags: CORRESPONDENCE Source Type: research

Reply to Cheng et al
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Van Hise, N. W., Manian, F. A. Tags: CORRESPONDENCE Source Type: research

Health Systems Can Play a Pivotal Role in Supporting Antimicrobial Stewardship
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Fakih, M. G., Guharoy, R., Hendrich, A., Haydar, Z. Tags: CORRESPONDENCE Source Type: research

Efficacy of Oral Vancomycin in Preventing Recurrent Clostridium difficile Infection in Patients Treated With Systemic Antimicrobial Agents
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Cheng, M. P., Parkes, L. O., Lee, T. C. Tags: CORRESPONDENCE Source Type: research

A Painful Leg Lump
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Bukhari, A., Chen, J. Z., Joffe, A. M., Chiu, I. Tags: ANSWER TO THE PHOTO QUIZ Source Type: research

Should Providers Discuss Breastfeeding With Women Living With HIV in High-Income Countries? An Ethical Analysis
As men and women with human immunodeficiency virus (HIV) are living longer, healthier lives and having children, many questions regarding reproduction in the context of HIV arise. One question is whether breastfeeding is an option for mothers living with HIV. The established recommendation is that women living with HIV in high-income countries avoid breastfeeding. However, some women may still choose to breastfeed for a variety of personal, social, or cultural reasons. Nonmaleficence ("do no harm") must be weighed against maternal autonomy. We propose that providers caring for women in this situation are ethically justifie...
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Johnson, G., Levison, J., Malek, J. Tags: HIV/AIDS Source Type: research

Multiplexed Molecular Diagnostics for Respiratory, Gastrointestinal, and Central Nervous System Infections
The development and implementation of highly multiplexed molecular diagnostic tests have allowed clinical microbiology laboratories to more rapidly and sensitively detect a variety of pathogens directly in clinical specimens. Current US Food and Drug Administration–approved multiplex panels target multiple different organisms simultaneously and can identify the most common pathogens implicated in respiratory viral, gastrointestinal, or central nervous system infections. This review summarizes the test characteristics of available assays, highlights the advantages and limitations of multiplex technology for infectious...
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Hanson, K. E., Couturier, M. R. Tags: MEDICAL MICROBIOLOGY Source Type: research

A Painful Leg Lump
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Tags: PHOTO QUIZ Source Type: research

Macracanthorhynchus ingens Infection in an 18-Month-Old Child in Florida: A Case Report and Review of Acanthocephaliasis in Humans
A case of acanthocephaliasis in an 18-month-old child caused by Macracanthorhynchus ingens is reported from Florida. This represents only the third documented case of this species in a human host. An overview of human cases of acanthocephaliasis in the literature is presented, along with a review of the biology, clinical manifestations and pathology in the human host, morphology, and diagnosis. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Mathison, B. A., Bishop, H. S., Sanborn, C. R., dos Santos Souza, S., Bradbury, R. Tags: BRIEF REPORTS Source Type: research

Galactomannan, {beta}-D-Glucan, and Polymerase Chain Reaction-Based Assays for the Diagnosis of Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis
We systematically reviewed and analyzed the available data for galactomannan (GM), β-D-glucan (BG), and polymerase chain reaction (PCR)–based assays to detect invasive fungal disease (IFD) in patients with pediatric cancer or undergoing hematopoietic stem cell transplantation when used as screening tools during immunosuppression or as diagnostic tests in patients presenting with symptoms such as fever during neutropenia (FN). Of 1532 studies screened, 25 studies reported on GM (n = 19), BG (n = 3), and PCR (n = 11). All fungal biomarkers demonstrated highly variable sensitivity, specificity, and positive predict...
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Lehrnbecher, T., Robinson, P. D., Fisher, B. T., Castagnola, E., Groll, A. H., Steinbach, W. J., Zaoutis, T. E., Negeri, Z. F., Beyene, J., Phillips, B., Sung, L. Tags: REVIEWARTICLES Source Type: research

Individualized Approaches Are Needed for Optimized Blood Cultures
Many strategies and technologies are available to improve blood culture (BC)–based diagnostics. The ideal approach to BCs varies between healthcare institutions. Institutions need to examine clinical needs and practices in order to optimize BC-based diagnostics for their site. Before laboratories consider offering rapid matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS) or expensive rapid panel-based molecular BC diagnostics, they should optimize preanalytical, analytical, and postanalytical processes and procedures surrounding BC systems. Several factors need to be considered...
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Banerjee, R., Özenci, V., Patel, R. Tags: VIEWPOINTS Source Type: research

Rectal Infection With Neisseria gonorrhoeae and Chlamydia trachomatis in Men in the United States
Conclusions. This analysis of a large number of male rectal specimens tested for GC and CT suggest that routine testing and timely repeat rectal GC and CT testing should be prioritized among men who report receptive rectal sex. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - October 27, 2016 Category: Infectious Diseases Authors: Tao, G., Hoover, K. W., Nye, M. B., Peters, P., Gift, T. L., Peruvemba, R., Body, B. A. Tags: ARTICLES AND COMMENTARIES Source Type: research