15 December News
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: NEWS Source Type: research

Table of Contents
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Subscriptions Page
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Masthead
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Editorial Board
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Editorial Advisory Board
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Cover
(Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - December 7, 2016 Category: Infectious Diseases Tags: Cover/Standing Material Source Type: research

Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction
The effectiveness of maternal immunization in preventing infant pertussis was first demonstrated in England, 1 year after the program using diphtheria–tetanus–5-component acellular pertussis–inactivated polio vaccine (dT5aP-IPV) was introduced in 2012. Vaccine effectiveness against laboratory-confirmed pertussis has been sustained >90% in the 3 years following its introduction, despite changing to another acellular vaccine with different antigen composition. Consistent with this, disease incidence in infants <3 months of age has remained low despite high activity persisting in those aged 1 year and ...
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Amirthalingam, G., Campbell, H., Ribeiro, S., Fry, N. K., Ramsay, M., Miller, E., Andrews, N. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

What Pertussis Mortality Rates Make Maternal Acellular Pertussis Immunization Cost-Effective in Low- and Middle-Income Countries? A Decision Analysis
Conclusions. For commonly used cost-effectiveness benchmarks, maternal aP immunization would be cost-effective in many LMICs only if the vaccine were offered at less than $1–$2/dose. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Russell, L. B., Pentakota, S. R., Toscano, C. M., Cosgriff, B., Sinha, A. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

An Assessment of the Cocooning Strategy for Preventing Infant Pertussis--United States, 2011
Conclusions. Low Tdap coverage among adult CCs reinforces the difficulty of implementing the cocooning strategy and the importance of vaccination during pregnancy to prevent infant pertussis. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Blain, A. E., Lewis, M., Banerjee, E., Kudish, K., Liko, J., McGuire, S., Selvage, D., Watt, J., Martin, S. W., Skoff, T. H. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

Influence of Population Demography and Immunization History on the Impact of an Antenatal Pertussis Program
Conclusions. While antenatal vaccination could potentially reduce infant mortality in LMICs, broader gains at the population level are likely to be achieved by focusing efforts on increasing DTP3 coverage. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Campbell, P. T., McVernon, J., McIntyre, P., Geard, N. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

Forecasting Epidemiological Consequences of Maternal Immunization
Conclusions. Maternal immunization has clear positive effects on infant burden of disease, lowering mean infant incidence. However, if maternally derived antibodies adversely affect the immunogenicity of the routine schedule, we predict eventual population-level repercussions that may lead to an overall increase in incidence in older age groups. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Bento, A. I., Rohani, P. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

The Effect of Maternal Pertussis Immunization on Infant Vaccine Responses to a Booster Pertussis-Containing Vaccine in Vietnam
Conclusions. The present results indicate that the blunting of infant pertussis responses induced by maternal immunization, measured after a primary series of aP vaccines, was resolved with the booster aP vaccine dose. These results add to the evidence for national and international decision makers on maternal immunization as a vaccination strategy for protection of young infants against infectious diseases. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Maertens, K., Hoang, T. T. H., Nguyen, T. D., Cabore, R. N., Duong, T. H., Huygen, K., Hens, N., Van Damme, P., Dang, D. A., Leuridan, E. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

Comparing the Yield of Nasopharyngeal Swabs, Nasal Aspirates, and Induced Sputum for Detection of Bordetella pertussis in Hospitalized Infants
Conclusions. Flocked nasopharyngeal swabs, nasopharyngeal aspirates, and induced sputum performed similarly for the detection of B. pertussis infection in young infants by PCR. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Nunes, M. C., Soofie, N., Downs, S., Tebeila, N., Mudau, A., de Gouveia, L., Madhi, S. A. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research

Bordetella pertussis Infection in South African HIV-Infected and HIV-Uninfected Mother-Infant Dyads: A Longitudinal Cohort Study
Conclusions. Bordetella pertussis identification was common among young infants with respiratory illness, most of whom were too young to be fully protected through direct vaccination. Vaccination of pregnant women might be a valuable strategy in a setting such us ours to prevent B. pertussis–associated illness in women and their young infants. (Source: Clinical Infectious Diseases)
Source: Clinical Infectious Diseases - November 11, 2016 Category: Infectious Diseases Authors: Nunes, M. C., Downs, S., Jones, S., van Niekerk, N., Cutland, C. L., Madhi, S. A. Tags: INFANT PERTUSSIS DISEASE BURDEN IN THE CONTEXT OF MATERNAL IMMUNIZATION STRATEGIES Source Type: research