The regulatory role and mechanism of USP14 in endothelial cell pyroptosis induced by coronary heart disease
CONCLUSION: USP14 stabilizes NLRP3 protein expression through deubiquitination, thereby facilitating endothelial cell pyroptosis in CHD. miR-15b-5p restrains endothelial cell pyroptosis by targeting USP14 expression.PMID:38073382 | DOI:10.3233/CH-232003 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Jie Gao Zhao Gao Source Type: research

Modulation of the capillary leakage by exogenous albumin in a rat model of endothelial glycocalyx damage
CONCLUSION: Exogenous albumin decreased the capillary leakage of albumin which was interpreted as a sign of maintained EG integrity.PMID:38073383 | DOI:10.3233/CH-232027 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: David Astapenko Marek Zrzavecky Diana Gorskaja Radomir Hyspler Alena Ticha Vera Radochova Christian Lehmann Manu L N G Malbrain Vladimir Cerny Robert G Hahn Source Type: research

Blood rheology and vascular function in sickle cell trait and sickle cell disease: From pathophysiological mechanisms to clinical usefulness
Clin Hemorheol Microcirc. 2023 Dec 7. doi: 10.3233/CH-238122. Online ahead of print.ABSTRACTSickle cell disease (SCD) is an autosomal recessive disorder. Although the molecular mechanisms at the origin of SCD have been well characterized, its clinical expression is highly variable. SCD is characterized by blood rheological abnormalities, increased inflammation and oxidative stress, and vascular dysfunction. Individuals with only one copy of the mutated β-globin gene have sickle cell trait (SCT) and are usually asymptomatic. The first part of this review focuses on the biological responses of SCT carriers during exercise a...
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Philippe Connes Source Type: research

Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients
CONCLUSION: Percentage of neutrophils, platelets, and thrombus density ratio are independent predictors of PE. The thrombosis density of DVT patients may be an index to predict the risk of PE and PTS in DVT patients.PMID:38073380 | DOI:10.3233/CH-231778 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Miao-Miao Yao Ting-Ting Lin Xu Shi Mei-Gui Chen Jia-Xiang Wu Yan-Ping Zhao Bao-Shan Lin Source Type: research

An observational study of microcirculation among healthy individuals by age and sex
CONCLUSIONS: This study revealed the range of microcirculatory parameters between different ages and sexes in healthy individuals. We found that blood pressure levels were correlated with microcirculatory parameters, especially in elders and female.PMID:38073381 | DOI:10.3233/CH-231807 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Yun-Ping Yang Ching-Tang Chiu Anne Chao Yu-Chang Yeh Wei-Zen Sun Chih-Min Liu Wing-Sum Chan Source Type: research

The regulatory role and mechanism of USP14 in endothelial cell pyroptosis induced by coronary heart disease
CONCLUSION: USP14 stabilizes NLRP3 protein expression through deubiquitination, thereby facilitating endothelial cell pyroptosis in CHD. miR-15b-5p restrains endothelial cell pyroptosis by targeting USP14 expression.PMID:38073382 | DOI:10.3233/CH-232003 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Jie Gao Zhao Gao Source Type: research

Modulation of the capillary leakage by exogenous albumin in a rat model of endothelial glycocalyx damage
CONCLUSION: Exogenous albumin decreased the capillary leakage of albumin which was interpreted as a sign of maintained EG integrity.PMID:38073383 | DOI:10.3233/CH-232027 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: David Astapenko Marek Zrzavecky Diana Gorskaja Radomir Hyspler Alena Ticha Vera Radochova Christian Lehmann Manu L N G Malbrain Vladimir Cerny Robert G Hahn Source Type: research

Blood rheology and vascular function in sickle cell trait and sickle cell disease: From pathophysiological mechanisms to clinical usefulness
Clin Hemorheol Microcirc. 2023 Dec 7. doi: 10.3233/CH-238122. Online ahead of print.ABSTRACTSickle cell disease (SCD) is an autosomal recessive disorder. Although the molecular mechanisms at the origin of SCD have been well characterized, its clinical expression is highly variable. SCD is characterized by blood rheological abnormalities, increased inflammation and oxidative stress, and vascular dysfunction. Individuals with only one copy of the mutated β-globin gene have sickle cell trait (SCT) and are usually asymptomatic. The first part of this review focuses on the biological responses of SCT carriers during exercise a...
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Philippe Connes Source Type: research

Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients
CONCLUSION: Percentage of neutrophils, platelets, and thrombus density ratio are independent predictors of PE. The thrombosis density of DVT patients may be an index to predict the risk of PE and PTS in DVT patients.PMID:38073380 | DOI:10.3233/CH-231778 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Miao-Miao Yao Ting-Ting Lin Xu Shi Mei-Gui Chen Jia-Xiang Wu Yan-Ping Zhao Bao-Shan Lin Source Type: research

An observational study of microcirculation among healthy individuals by age and sex
CONCLUSIONS: This study revealed the range of microcirculatory parameters between different ages and sexes in healthy individuals. We found that blood pressure levels were correlated with microcirculatory parameters, especially in elders and female.PMID:38073381 | DOI:10.3233/CH-231807 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Yun-Ping Yang Ching-Tang Chiu Anne Chao Yu-Chang Yeh Wei-Zen Sun Chih-Min Liu Wing-Sum Chan Source Type: research

The regulatory role and mechanism of USP14 in endothelial cell pyroptosis induced by coronary heart disease
CONCLUSION: USP14 stabilizes NLRP3 protein expression through deubiquitination, thereby facilitating endothelial cell pyroptosis in CHD. miR-15b-5p restrains endothelial cell pyroptosis by targeting USP14 expression.PMID:38073382 | DOI:10.3233/CH-232003 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Jie Gao Zhao Gao Source Type: research

Modulation of the capillary leakage by exogenous albumin in a rat model of endothelial glycocalyx damage
CONCLUSION: Exogenous albumin decreased the capillary leakage of albumin which was interpreted as a sign of maintained EG integrity.PMID:38073383 | DOI:10.3233/CH-232027 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: David Astapenko Marek Zrzavecky Diana Gorskaja Radomir Hyspler Alena Ticha Vera Radochova Christian Lehmann Manu L N G Malbrain Vladimir Cerny Robert G Hahn Source Type: research

Blood rheology and vascular function in sickle cell trait and sickle cell disease: From pathophysiological mechanisms to clinical usefulness
Clin Hemorheol Microcirc. 2023 Dec 7. doi: 10.3233/CH-238122. Online ahead of print.ABSTRACTSickle cell disease (SCD) is an autosomal recessive disorder. Although the molecular mechanisms at the origin of SCD have been well characterized, its clinical expression is highly variable. SCD is characterized by blood rheological abnormalities, increased inflammation and oxidative stress, and vascular dysfunction. Individuals with only one copy of the mutated β-globin gene have sickle cell trait (SCT) and are usually asymptomatic. The first part of this review focuses on the biological responses of SCT carriers during exercise a...
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Philippe Connes Source Type: research

Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients
CONCLUSION: Percentage of neutrophils, platelets, and thrombus density ratio are independent predictors of PE. The thrombosis density of DVT patients may be an index to predict the risk of PE and PTS in DVT patients.PMID:38073380 | DOI:10.3233/CH-231778 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Miao-Miao Yao Ting-Ting Lin Xu Shi Mei-Gui Chen Jia-Xiang Wu Yan-Ping Zhao Bao-Shan Lin Source Type: research

An observational study of microcirculation among healthy individuals by age and sex
CONCLUSIONS: This study revealed the range of microcirculatory parameters between different ages and sexes in healthy individuals. We found that blood pressure levels were correlated with microcirculatory parameters, especially in elders and female.PMID:38073381 | DOI:10.3233/CH-231807 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Yun-Ping Yang Ching-Tang Chiu Anne Chao Yu-Chang Yeh Wei-Zen Sun Chih-Min Liu Wing-Sum Chan Source Type: research