Closing the Gap between Diagnostic Test Accuracy Reviews and Reporting Guidelines: The PRISMA-Diagnostic Test Accuracy Statement [Editorials]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 28, 2019 Category: Chemistry Authors: Chaimani, A., Ravaud, P. Tags: Editorials Source Type: research
Proteins and Clinical Mass Spectrometry: A Fairy Tale? [Editorials]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 28, 2019 Category: Chemistry Authors: van den Broek, I. Tags: Proteomics and Protein Markers Editorials Source Type: research
Extreme PCR Meets High-Speed Melting: A Step Closer to Molecular Diagnostics "While You Wait" [Editorials]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 28, 2019 Category: Chemistry Authors: Makrigiorgos, G. M. Tags: Molecular Diagnostics and Genetics Editorials Source Type: research
Say "NO" to Erectile Dysfunction [Unveiling the Right Side]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Anand, U. Tags: Unveiling the Right Side Source Type: research
Evolution of Sperm Testing--A Bright Future? [Unveiling the Right Side]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Kricka, L. J., Wilding, P. Tags: Unveiling the Right Side Source Type: research
Highest Testosterone Concentration Ever: Pathology or Laboratory Error? [What Is Your Guess?]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Tesfazghi, M. T., Farnsworth, C. W. Tags: Endocrinology and Metabolism What Is Your Guess? Source Type: research
The ERSPC Study: Quality Takes Time and Perseverance [Citation Classic]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Roobol, M. J., Carlsson, S. V. Tags: Other Areas of Clinical Chemistry, Citation Classics Source Type: research
The Vaginal Microbiome of Transgender Men [Molecular Diagnostics and Genetics]
CONCLUSIONS:
The vaginal microbiome of transgender men who were assigned a female sex at birth and use testosterone may differ from that of cisgender women. Intravaginal estrogen administration may reduce these differences by promoting colonization with Lactobacillus species and decreasing α diversity. (Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Winston McPherson, G., Long, T., Salipante, S. J., Rongitsch, J. A., Hoffman, N. G., Stephens, K., Penewit, K., Greene, D. N. Tags: Molecular Diagnostics and Genetics Source Type: research
Adding the Team into T1 Translational Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis [Cancer Diagnostics]
CONCLUSIONS:
In this case study, we documented the inferential benefits of multidisciplinary team science when the team's collaboration and coordination led to the identification of threats to validity and the implementation of appropriate solutions. (Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Marrone, M. T., Joshu, C. E., Peskoe, S. B., De Marzo, A. M., Heaphy, C. M., Lupold, S. E., Meeker, A. K., Platz, E. A. Tags: Other Areas of Clinical Chemistry Cancer Diagnostics Source Type: research
Increased Ferritin Concentration and Risk of Atrial Fibrillation and Heart Failure in Men and Women: Three Studies of the Danish General Population Including 35799 Individuals [Hematology]
CONCLUSIONS:
Increased ferritin concentration is associated with increased risk of atrial fibrillation in the general population. (Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Mikkelsen, L. F., Nordestgaard, B. G., Schnohr, P., Ellervik, C. Tags: Hematology Source Type: research
Impact of Hormone Therapy on Laboratory Values in Transgender Patients [Endocrinology and Metabolism]
CONCLUSIONS:
Changes occur in several common laboratory parameters for patients on HT. Some laboratory values changed to match the gender identity, whereas others remained unchanged or were intermediate from the baseline values. These findings will help guide interpretation of laboratory test results in transgender patients taking HT. (Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: SoRelle, J. A., Jiao, R., Gao, E., Veazey, J., Frame, I., Quinn, A. M., Day, P., Pagels, P., Gimpel, N., Patel, K. Tags: Current Issues in Laboratory Medicine Endocrinology and Metabolism Source Type: research
Reduced Testicular Steroidogenesis and Increased Semen Oxidative Stress in Male Partners as Novel Markers of Recurrent Miscarriage [Endocrinology and Metabolism]
CONCLUSIONS:
Our data suggest that male partners of women with RPL have impaired reproductive endocrine function, increased levels of semen ROS, and sperm DNA fragmentation. Routine reproductive assessment of the male partners may be beneficial in RPL. (Source: Clinical Chemistry)
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Jayasena, C. N., Radia, U. K., Figueiredo, M., Revill, L. F., Dimakopoulou, A., Osagie, M., Vessey, W., Regan, L., Rai, R., Dhillo, W. S. Tags: Endocrinology and Metabolism Source Type: research
Male Contraceptive Development: Update on Novel Hormonal and Nonhormonal Methods [Reviews]
BACKGROUND:
Development of new methods of male contraception would address an unmet need for men to control their fertility and could increase contraceptive options for women. Pharmaceutical research and development for male contraception was active in the 1990s but has been virtually abandoned. The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has supported a contraceptive development program since 1969 and supports the majority of hormonal male contraceptive development. Nonhormonal methods are also in development but are at earlier stages.
CONTENT:
Several hormonal male contrac...
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Long, J. E., Lee, M. S., Blithe, D. L. Tags: Other Areas of Clinical Chemistry Reviews Source Type: research
Impact of Paternal Age at Conception on Human Health [Reviews]
BACKGROUND:
The effect of maternal age at conception on various aspects of offspring health is well documented and often discussed. We seldom hear about the paternal age effect on offspring health, although the link is now almost as solid as with maternal age. The causes behind this, however, are drastically different between males and females.
CONTENT:
In this review article, we will first examine documented physiological changes linked to paternal age effect. We will start with all morphological aspects of the testis that have been shown to be altered with aging. We will then move on to all the parameters of spermatogen...
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Simard, M., Laprise, C., Girard, S. L. Tags: Other Areas of Clinical Chemistry Reviews Source Type: research
Differences between Men and Women in Mortality and the Health Dimensions of the Morbidity Process [Reviews]
BACKGROUND:
Do men have worse health than women? This question is addressed by examining sex differences in mortality and the health dimensions of the morbidity process that characterize health change with age. We also discuss health differences across historical time and between countries.
CONTENT:
Results from national-level surveys and data systems are used to identify male/female differences in mortality rates, prevalence of diseases, physical functioning, and indicators of physiological status. Male/female differences in health outcomes depend on epidemiological and social circumstances and behaviors, and many are no...
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Crimmins, E. M., Shim, H., Zhang, Y. S., Kim, J. K. Tags: Other Areas of Clinical Chemistry Reviews Source Type: research
