Improving the transgender patient experience in the breast imaging center
Clin Imaging. 2024 Mar 11;109:110119. doi: 10.1016/j.clinimag.2024.110119. Online ahead of print.ABSTRACTPURPOSE: This review discusses how breast centers can optimize patient experience scores among transgender patients.FINDINGS: High patient experience scores impact patient care and compliance. Increased regulations have been enacted to ensure that health systems are effectively meeting the health concerns of sexual minorities. This will be reflected in the patient experience surveys. A leading patient survey will be assessed to help breast imaging centers optimize the transgender patient experience and question types wi...
Source: Clinical Breast Cancer - March 15, 2024 Category: Cancer & Oncology Authors: Karen E Gerlach Jessica W T Leung Source Type: research
Integrating single-cell and spatial transcriptomes reveals COL4A1/2 facilitates the spatial organisation of stromal cells differentiation in breast phyllodes tumours
CONCLUSIONS: Our study demonstrates that COL4A1/2 shapes the spatial structure of stromal cell differentiation and has important clinical implications for accurate diagnosis of breast PTs.PMID:38481388 | PMC:PMC10938066 | DOI:10.1002/ctm2.1611 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Xia Li Xuewen Yu Jiaxin Bi Xu Jiang Lu Zhang Zhixin Li Mumin Shao Source Type: research
Synergistic effects of epoxyazadiradione (EAD) and paclitaxel against triple-negative breast cancer cells
CONCLUSION: To conclude, EAD could be the drug of choice for combined treatment with paclitaxel in a chemotherapy regimen.PMID:38482560 | DOI:10.1111/fcp.13000 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Kunnathully Sudhan Sijisha Rajitha Anusha Sulochana Priya Source Type: research
Approach to the care process by nurse case managers in a breast unit
CONCLUSIONS: The management of nurse case managers in breast units contributes to improving or speeding up times, in accordance with international guidelines, helping this approach in the continuity of the care process for women referred after screening for breast cancer detection.PMID:38484933 | DOI:10.1016/j.enfcle.2024.03.004 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Mar ía Isabel López-Pérez Alonso Molina-Rodr íguez Francisco David Harillo-Acevedo Ascensi ón Guillén-Martínez Mar ía Patricia Palacio-Gaviria Source Type: research
Stromal Type I Collagen in Breast Cancer: Correlation to Prognostic Biomarkers and Prediction of Chemotherapy Response
CONCLUSION: Low stromal type I collagen mRNA and protein expression are associated with unfavourable tumour characteristics in breast cancer. Stromal type I collagen might predict chemotherapy response.PMID:38485557 | DOI:10.1016/j.clbc.2024.02.015 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Malin Jansson Jessica Lindberg Gunilla Rask Johan Svensson Ola Billing Anoosheh Nazemroaya Anette Berglund Fredrik W ärnberg Malin Sund Source Type: research
Integrating single-cell and spatial transcriptomes reveals COL4A1/2 facilitates the spatial organisation of stromal cells differentiation in breast phyllodes tumours
CONCLUSIONS: Our study demonstrates that COL4A1/2 shapes the spatial structure of stromal cell differentiation and has important clinical implications for accurate diagnosis of breast PTs.PMID:38481388 | DOI:10.1002/ctm2.1611 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Xia Li Xuewen Yu Jiaxin Bi Xu Jiang Lu Zhang Zhixin Li Mumin Shao Source Type: research
Synergistic effects of epoxyazadiradione (EAD) and paclitaxel against triple-negative breast cancer cells
CONCLUSION: To conclude, EAD could be the drug of choice for combined treatment with paclitaxel in a chemotherapy regimen.PMID:38482560 | DOI:10.1111/fcp.13000 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Kunnathully Sudhan Sijisha Rajitha Anusha Sulochana Priya Source Type: research
The promise of AI in personalized breast cancer screening: are we there yet?
Nat Rev Clin Oncol. 2024 Mar 12. doi: 10.1038/s41571-024-00877-z. Online ahead of print.NO ABSTRACTPMID:38472364 | DOI:10.1038/s41571-024-00877-z (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Despina Kontos Source Type: research
An approach for improvement of the accuracy of cancer gene panel testing
CONCLUSION: We identified various factors associated with efficient and accurate CGP testing using relevant information obtained from real-world data, suggesting that thorough selection and preparation of tissue sections could optimize CGP and maximize useful information.PMID:38472663 | DOI:10.1007/s10147-024-02483-6 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Kiyomi Imoto Hiroyuki Yamamoto Chie Ohkawa Naoki Shimada Ryo Ikuzawa Hiroyuki Takeda Tatsuru Ohhara Yasuyuki Kojima Naoki Furuya Ai Motoyoshi Ohsuke Migita Asami Kuga Takayuki Keira Hirotake Wakamatsu Tomoo Sato Nobuyuki Oike Junki Koike Yoshihisa Yamano Source Type: research
Pharmacogenetics of tamoxifen in breast cancer patients of African descent: Lack of data
Clin Transl Sci. 2024 Mar;17(3):e13761. doi: 10.1111/cts.13761.ABSTRACTTamoxifen, a selective estrogen receptor modulator, is used to treat hormone receptor-positive breast cancer. Tamoxifen acts as a prodrug, with its primary therapeutic effect mediated by its principal metabolite, endoxifen. However, tamoxifen has complex pharmacokinetics involving several drug-metabolizing enzymes and transporters influencing its disposition. Genes encoding enzymes involved in tamoxifen disposition exhibit genetic polymorphisms which vary widely across world populations. This review highlights the lack of data on tamoxifen pharmacogenet...
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Bianca Kruger Delva Shamley Nyarai Desiree Soko Collet Dandara Source Type: research
Exploring the molecular mechanisms network of breast cancer by multi-omics analysis
CONCLUSION: These findings pinpoint four crucial genes in BC progression, offering targets for further research and therapy. Their connections to immune infiltration and chemotherapy sensitivity underscore complex interactions in the tumor microenvironment.PMID:38477438 | DOI:10.1111/ajco.14052 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Wei Jiang Yanjun Zhang Qiuqiong Wang Source Type: research
Assessment of TUFT1 and Rac1-GTP levels in triple-negative breast cancer patients: clinical and pathological correlations
CONCLUSION: A significant correlation was identified between the levels of TUFT1 and Rac1-GTP expressions in the cancerous tissues of patients with TNBC, suggesting a close association with the progression of TNBC. The two molecules play significant roles in facilitating an early diagnosis and treatment of TNBC.PMID:38478261 | DOI:10.1007/s12094-024-03426-3 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Su-Fang Shi Rui-Xi Cai Yan-Fei Ren Yong Li Shuo Li Tian-Lu Yin Dong-Xiao Jia Yong-Jun Li Source Type: research
Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline
J Clin Oncol. 2024 Mar 13:JCO2302596. doi: 10.1200/JCO.23.02596. Online ahead of print.ABSTRACTPURPOSE: To guide clinicians, adults with cancer, caregivers, researchers, and oncology institutions on the medical use of cannabis and cannabinoids, including synthetic cannabinoids and herbal cannabis derivatives; single, purified cannabinoids; combinations of cannabis ingredients; and full-spectrum cannabis.METHODS: A systematic literature review identified systematic reviews, randomized controlled trials (RCTs), and cohort studies on the efficacy and safety of cannabis and cannabinoids when used by adults with cancer. Outcome...
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Ilana M Braun Kari Bohlke Donald I Abrams Holly Anderson Lynda G Balneaves Gil Bar-Sela Daniel W Bowles Peter R Chai Anuja Damani Arjun Gupta Sigrun Hallmeyer Ishwaria M Subbiah Chris Twelves Mark S Wallace Eric J Roeland Source Type: research
Doxorubicin and Breast Cancer Risk: The Importance of Long-Term Follow-Up in Curable Cancers
J Clin Oncol. 2024 Mar 13:JCO2302763. doi: 10.1200/JCO.23.02763. Online ahead of print.NO ABSTRACTPMID:38478798 | DOI:10.1200/JCO.23.02763 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: John Radford Source Type: research
Endocrine and Targeted Therapy for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer-Capivasertib-Fulvestrant: ASCO Rapid Recommendation Update
J Clin Oncol. 2024 Mar 13:JCO2400248. doi: 10.1200/JCO.24.00248. Online ahead of print.ABSTRACTASCO Rapid Recommendation Updates highlight revisions to select ASCO guideline recommendations as a response to the emergence of new and practice-changing data. The rapid updates are supported by an evidence review and follow the guideline development processes outlined in the ASCO Guideline Methodology Manual. The goal of these articles is to disseminate updated recommendations, in a timely manner, to better inform health practitioners and the public on the best available cancer care options. Guidelines and updates are not inten...
Source: Clinical Breast Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Harold J Burstein Angela DeMichele Lesley Fallowfield Mark R Somerfield N Lynn Henry Biomarker Testing and Endocrine and Targeted Therapy in Metastatic Breast Cancer Expert Panels Biomarker Testing and Endocrine and Targeted Therapy in Metastatic Breast C Source Type: research
