Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study
ConclusionThis study will provide valuable insights into biomarkers for NS and serve as a biorepository for future studies. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

NT-pro BNP level at dialysis initiation is a useful biomarker for predicting hospitalization for ischemic heart disease
ConclusionNT-proBNP measurement at the initiation of dialysis therapy is useful to predict later hospitalization for IHD.Trial registration: UMIN000010806. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Urine albumin-to-creatinine ratio diurnal variation rate predicts outcomes in idiopathic membranous nephropathy
ConclusionUACR diurnal variation using spot urinary protein is a simpler way to predict nephrotic outcomes and is a highly sensitive screening tool for identifying patients who should undergo further comprehensive risk assessment. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Cytosolic mtDNA –cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome
ConclusionThis study demonstrated that the cGAS –STING axis was triggered by cytosolic mtDNA and participated in the development of S-AKI by activating NLRP3 inflammasome. Reducing cytosolic mtDNA accumulation or inhibiting the cGAS–STING axis may be potential therapeutic targets for S-AKI. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Prevalence and prognosis of severe hyperkalemia in the emergency department
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

NT-pro BNP level at dialysis initiation is a useful biomarker for predicting hospitalization for ischemic heart disease
ConclusionNT-proBNP measurement at the initiation of dialysis therapy is useful to predict later hospitalization for IHD.Trial registration: UMIN000010806. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Urine albumin-to-creatinine ratio diurnal variation rate predicts outcomes in idiopathic membranous nephropathy
ConclusionUACR diurnal variation using spot urinary protein is a simpler way to predict nephrotic outcomes and is a highly sensitive screening tool for identifying patients who should undergo further comprehensive risk assessment. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Cytosolic mtDNA –cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome
ConclusionThis study demonstrated that the cGAS –STING axis was triggered by cytosolic mtDNA and participated in the development of S-AKI by activating NLRP3 inflammasome. Reducing cytosolic mtDNA accumulation or inhibiting the cGAS–STING axis may be potential therapeutic targets for S-AKI. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Prevalence and prognosis of severe hyperkalemia in the emergency department
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 19, 2024 Category: Urology & Nephrology Source Type: research

Frailty and dialysis initiation in the super-elderly
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 11, 2024 Category: Urology & Nephrology Source Type: research

A case series of Fabry diseases with CKD in Japan
ConclusionsThis case series revealed the actual clinical practice of FD patients with CKD. In particular, we found cases in which patients had proteinuria, but were not treated with RAS inhibitors. The database was shown to be useful in assessing the clinical patterns of patients with rare diseases. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 9, 2024 Category: Urology & Nephrology Source Type: research

Correction to: Efficacy and safety of entecavir for hepatitis B virus-associated glomerulonephritis with renal insufficiency
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - January 4, 2024 Category: Urology & Nephrology Source Type: research