Clinical and Experimental Nephrology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Detecting and exploring kidney-derived extracellular vesicles in plasma
ConclusionOur findings demonstrate the potential usefulness of kidney-derived sEVs in plasma in future research for kidney diseases. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 4, 2024 Category: Urology & Nephrology Source Type: research

Association between glycated albumin and sudden death in patients undergoing hemodialysis
ConclusionSerum GA levels were significantly associated with sudden death in patients undergoing hemodialysis. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - March 4, 2024 Category: Urology & Nephrology Source Type: research

Comparison between the 0- and 30-s balloon dilation time in percutaneous transluminal angioplasty for restenosed arteriovenous fistula among hemodialysis patients: a multicenter, prospective, randomized trial (CARP study)
ConclusionThe presenting data suggest that 30-s dilation potentially results in a better 3-month patency rate than 0-s dilation in HD patients with restenosis after PTA. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 28, 2024 Category: Urology & Nephrology Source Type: research

Cell division cycle 42 attenuates high glucose-treated renal tubular epithelial cell apoptosis, fibrosis, and inflammation, but activates the PAK1/AKT pathway
ConclusionCDC42 may retard DN progression via its regulation of renal tubular epithelial cell functions, which may be due to its stimulation of the PAK1/AKT pathway. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 28, 2024 Category: Urology & Nephrology Source Type: research

Clinical significance of amphiregulin in patients with chronic kidney disease
ConclusionSerum soluble AREG levels were significantly correlated with renal function, and changes in renal function after 2 and 3 years, indicating that serum soluble AREG levels might serve as a biomarker of renal function and renal prognosis in CKD. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

Effects of sodium-glucose co-transporter 2 inhibitors on ultrafiltration in patients with peritoneal dialysis: a protocol for a randomized, double-blind, placebo-controlled, crossover trial (EMPOWERED)
ConclusionsThis trial aims to assess the benefit of SGLT2 inhibitors in fluid management with a novel mechanism of action in patients on PD. It will also provide insights into the effects of SGLT2 inhibitors on solute transport across the peritoneal membrane and residual renal function. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

Preference for anti-phospholipase A2 receptor antibody assay in patients with suspected membranous nephropathy: a survey study on medical practice after publication of Japanese Guidelines for Nephrotic Syndrome 2020
ConclusionThe results of this study suggest that a significant proportion of nephrologists in Japan have no experience in performing anti-PLA2R antibody assays, and that the assays may be hampered by the limited capabilities of the current workplace and the financial burden on facilities and patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

A multi-center randomized controlled trial to investigate potential effects of exercise therapy on renal function stratified by renal disorders and renal pathology: beneficial or harmful effect in immunoglobulin a nephropathy
ConclusionET did not improve renal function overall in CKD patients but might help maintain renal function in patients with IgA nephropathy. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

A survey of environmental sustainability in Japanese dialysis facilities
ConclusionsFollowing the UK, Australia and New Zealand, and Portugal, this is the fourth Green Survey to be conducted, and the first on environmental sustainability among kidney health-care providers in Japan. The results indicated that daily activities for environmental protection are still lacking at many facilities, even though the management of dialysis treatment during a natural disaster is well conducted. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

Effect of ferric citrate hydrate on fibroblast growth factor 23 and platelets in non-dialysis-dependent chronic kidney disease and non-chronic kidney disease patients with iron deficiency anemia
ConclusionRegardless of CKD status, iron replacement with FC decreased elevated cFGF23 levels and normalized elevated PLT in patients with IDA.Clinical trial registration numberjRCT2080223943. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

Urinary podocyte markers of disease activity, therapeutic efficacy, and long-term outcomes in acute and chronic kidney diseases
AbstractA critical degree of podocyte depletion causes glomerulosclerosis, and persistent podocyte loss in glomerular diseases drives the progression to end-stage kidney disease. The extent of podocyte injury at a point in time can be histologically assessed by measuring podocyte number, size, and density ( “Biopsy podometrics”). However, repeated invasive renal biopsies are associated with increased risk and cost. A noninvasive method for assessing podocyte injury and depletion is required. Albuminuria and proteinuria do not always correlate with disease activity. Podocytes are located on the urin ary space side of th...
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research

Perspectives on the optimal timing of advance care planning among Japanese patients undergoing dialysis and clinicians: a cross-sectional study
ConclusionsWhile fewer than 11% of patients undergoing dialysis and their clinicians enrolled in our study had participated in advance care planning, most indicated that they would be comfortable initiating the discussion around the time of dialysis initiation. These findings suggest untapped opportunities to engage patients in advance care planning early in the course of their dialysis. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - February 25, 2024 Category: Urology & Nephrology Source Type: research