Prognostic value of proteinuria monitoring in anti-neutrophil cytoplasmic antibody-associated vasculitis
ConclusionThe presence of proteinuria at 6  months after induction therapy and low renal function was significantly associated with a higher risk of stage 4/5 CKD in patients with AAV. Monitoring for proteinuria after induction therapy may help predict poor renal outcomes in patients with AAV. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Analysis of the ratio of urinary beta-2-microgobulin to total protein concentration in children with isolated tubulointerstitial disease
ConclusionIn children with tubulointerstitial diseases, the urinary β2-MG concentration may be approximately 8.5% of the TP concentration. The possibility of presenting with glomerular disease should be considered in patients with a ratio of urinary β2-MG to TP concentration of <  22.3 (µg/mg). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Sore thumb syndrome
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials
ConclusionThese patient-reported satisfaction outcomes support the use of molidustat as a patient-centered treatment option for CKD-related anemia.Registration of clinical trialsClinicalTrials.gov Identifier: NCT03350321 (November 22, 2017).ClinicalTrials.gov Identifier: NCT03350347 (November 22, 2017). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Anti-SARS-CoV-2 IgG antibody titer after BNT162b2 mRNA COVID-19 vaccination in Japanese patients who underwent renal replacement therapy, hemodialysis, peritoneal dialysis, and kidney transplantation
ConclusionsRRT patients, particularly KT recipients, exhibited poor vaccine responses. Booster vaccination would be beneficial for HD and PD patients; however, its effect in KT recipients was mild. Further COVID-19 vaccinations using the latest vaccine or alternative procedures should be considered in RRT patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research