Effect of indexed glomerular filtration rate according to age
ConclusionFor children older than 12  years both normalisation methods can be used, but for children younger than 12 years there are differences. We believe that in children under 12 years of age, GFR should be normalised by ECFV. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - May 4, 2023 Category: Urology & Nephrology Source Type: research

Renal protective effects of astragalus root in rat models of chronic kidney disease
ConclusionThis study suggests that astragalus root slowed CKD progression, possibly through the suppression of oxidative stress and the renin –angiotensin system. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - May 4, 2023 Category: Urology & Nephrology Source Type: research

Sex differences in the association between urate metabolism and kidney outcomes in patients with chronic kidney disease
ConclusionIn CKD, lower CUA was independently associated with poor kidney outcomes only in men, and in both sexes, there was no association of SUA with kidney outcomes. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 28, 2023 Category: Urology & Nephrology Source Type: research

Efficacy and safety of entecavir for hepatitis B virus-associated glomerulonephritis with renal insufficiency
ConclusionsEntecavir slows the progression of renal function impairment in HBV-GN and exerts a significant renal protective effect. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 28, 2023 Category: Urology & Nephrology Source Type: research

Sex differences in the association between urate metabolism and kidney outcomes in patients with chronic kidney disease
ConclusionIn CKD, lower CUA was independently associated with poor kidney outcomes only in men, and in both sexes, there was no association of SUA with kidney outcomes. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 28, 2023 Category: Urology & Nephrology Source Type: research

Efficacy and safety of entecavir for hepatitis B virus-associated glomerulonephritis with renal insufficiency
ConclusionsEntecavir slows the progression of renal function impairment in HBV-GN and exerts a significant renal protective effect. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 28, 2023 Category: Urology & Nephrology Source Type: research

Analysis of the ratio of urinary beta-2-microglobulin to total protein concentration in children with isolated tubulointerstitial disease
ConclusionIn children with tubulointerstitial diseases, the urinary β2-MG concentration may be approximately 8.5% of the TP concentration. The possibility of presenting with glomerular disease should be considered in patients with a ratio of urinary β2-MG to TP concentration of <  22.3 (µg/mg). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

CD4  + and CD8 + T-lymphocyte number as predictive marker of relapse after rituximab treatment in childhood-onset refractory nephrotic syndrome
ConclusionsLower CD4  + and CD8 + cell counts in the early phase after rituximab administration may predict a lower risk of relapse. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Prognostic impact of renal sinus fat accumulation in patients with chronic kidney disease
ConclusionsAmong those with CKD who required renal biopsy, the amount of renal sinus fat was associated with poor renal outcomes accompanied by systemic hypertension. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Prognostic value of proteinuria monitoring in anti-neutrophil cytoplasmic antibody-associated vasculitis
ConclusionThe presence of proteinuria at 6  months after induction therapy and low renal function was significantly associated with a higher risk of stage 4/5 CKD in patients with AAV. Monitoring for proteinuria after induction therapy may help predict poor renal outcomes in patients with AAV. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Analysis of the ratio of urinary beta-2-microgobulin to total protein concentration in children with isolated tubulointerstitial disease
ConclusionIn children with tubulointerstitial diseases, the urinary β2-MG concentration may be approximately 8.5% of the TP concentration. The possibility of presenting with glomerular disease should be considered in patients with a ratio of urinary β2-MG to TP concentration of <  22.3 (µg/mg). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Sore thumb syndrome
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials
ConclusionThese patient-reported satisfaction outcomes support the use of molidustat as a patient-centered treatment option for CKD-related anemia.Registration of clinical trialsClinicalTrials.gov Identifier: NCT03350321 (November 22, 2017).ClinicalTrials.gov Identifier: NCT03350347 (November 22, 2017). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research

Anti-SARS-CoV-2 IgG antibody titer after BNT162b2 mRNA COVID-19 vaccination in Japanese patients who underwent renal replacement therapy, hemodialysis, peritoneal dialysis, and kidney transplantation
ConclusionsRRT patients, particularly KT recipients, exhibited poor vaccine responses. Booster vaccination would be beneficial for HD and PD patients; however, its effect in KT recipients was mild. Further COVID-19 vaccinations using the latest vaccine or alternative procedures should be considered in RRT patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 24, 2023 Category: Urology & Nephrology Source Type: research