Association between phosphate binder pill burden and mortality risk in patients on maintenance hemodialysis: a single-center cohort study with 7-year follow-up of 513 patients
ConclusionsDialysis patients prescribed a higher rate of PB pills to all medications exhibited a lower mortality risk, possibly due to their better nutritional status. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - August 14, 2023 Category: Urology & Nephrology Source Type: research

Kidney function monitoring and trajectories in patients with atrial fibrillation
ConclusionThe frequency of kidney function monitoring in patients with AF increased with worsening KDIGO risk category and adhered to KDIGO guidelines in approximately three quarters of patients. A minority of patients had moderate to severe eGFR impairment, of whom most remained stable over 1  year. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - August 14, 2023 Category: Urology & Nephrology Source Type: research

A systematic review for prevention of cisplatin-induced nephrotoxicity using different hydration protocols and meta-analysis for magnesium hydrate supplementation
ConclusionThere has been uncertainty regarding the best method to prevent CIN. Our results highlight the potentially protective effect of magnesium supplementation during hydration. This study is registered in PROSPERO, CRD42020212682. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - August 2, 2023 Category: Urology & Nephrology Source Type: research

Demographics and treatment of patients with primary membranoproliferative glomerulonephritis in Japan using a national registry of clinical personal records
ConclusionThe national registry of clinical personal records of primary MPGN could provide an informative insight into the characteristics, clinical features, and treatment approaches for patients with primary MPGN in Japan. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 29, 2023 Category: Urology & Nephrology Source Type: research

d-Serine as a sensor and effector of the kidney
Abstractd-Serine, a rare enantiomer of serine, is a biomarker of kidney disease and function. The level ofd-serine in the human body is precisely regulated through the urinary clearance of the kidney, and its clearance serves as a new measure of glomerular filtration rate with a lower bias than creatinine clearance.d-Serine also has a direct effect on the kidneys and mediates the cellular proliferation of tubular cells via mTOR signaling and induces kidney remodeling as a compensatory reaction to the loss of kidney mass. In living kidney donors, the removal of the kidney results in an increase in bloodd-serine level, which...
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Development and validation of a nomogram to predict the risk of renal replacement therapy among acute kidney injury patients in intensive care unit
ConclusionThe nomogram developed in this study was highly accurate for RRT prediction with potential application value. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Angiotensin II receptor blockers and bone fracture in chronic kidney disease patients: the Fukuoka kidney disease Registry Study
ConclusionsThe present study showed that administering ARB was significantly associated with a lower frequency of bone fracture history. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Clinical impact of catheter insertion for peritoneal dialysis on patient survival and catheter-related complications
ConclusionsPlanned sequential renal replacement therapy including hybrid hemodialysis, complete hemodialysis, and kidney transplantation after PD is important for improving patient outcomes. PD catheter insertion by SMAP may not be mandatory in our clinical practice. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

d-Serine as a sensor and effector of the kidney
Abstractd-Serine, a rare enantiomer of serine, is a biomarker of kidney disease and function. The level ofd-serine in the human body is precisely regulated through the urinary clearance of the kidney, and its clearance serves as a new measure of glomerular filtration rate with a lower bias than creatinine clearance.d-Serine also has a direct effect on the kidneys and mediates the cellular proliferation of tubular cells via mTOR signaling and induces kidney remodeling as a compensatory reaction to the loss of kidney mass. In living kidney donors, the removal of the kidney results in an increase in bloodd-serine level, which...
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Development and validation of a nomogram to predict the risk of renal replacement therapy among acute kidney injury patients in intensive care unit
ConclusionThe nomogram developed in this study was highly accurate for RRT prediction with potential application value. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Angiotensin II receptor blockers and bone fracture in chronic kidney disease patients: the Fukuoka kidney disease Registry Study
ConclusionsThe present study showed that administering ARB was significantly associated with a lower frequency of bone fracture history. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Clinical impact of catheter insertion for peritoneal dialysis on patient survival and catheter-related complications
ConclusionsPlanned sequential renal replacement therapy including hybrid hemodialysis, complete hemodialysis, and kidney transplantation after PD is important for improving patient outcomes. PD catheter insertion by SMAP may not be mandatory in our clinical practice. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 27, 2023 Category: Urology & Nephrology Source Type: research

Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials
ConclusionThese patient-reported satisfaction outcomes support the use of molidustat as a patient-centered treatment option for CKD-related anemia.Registration of clinical trialsClinicalTrials.gov Identifier: NCT03350321 (November 22, 2017).ClinicalTrials.gov Identifier: NCT03350347 (November 22, 2017). (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - July 26, 2023 Category: Urology & Nephrology Source Type: research