Clinical and Experimental Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Systems Medicine Approach Reveals Disordered Immune System and Lipid Metabolism in Multiple Sclerosis Patients
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 30, 2017 Category: Allergy & Immunology Authors: Mehrdad Pazhouhandeh, Mohammad ‐Ali Sahraian, Seyed Davar Siadat, Abolfazl Fateh, Farzam Vaziri, Fatemeh Tabrizi, Faezeh Ajorloo, Arash Keshavarzi Arshadi, Elnaz Fatemi, Somaye Piri Gavgani, Fereidoun Mahboudi, Fatemeh Rahimi Jamnani Tags: Original Article Source Type: research

Alpha ‐defensins (α‐Defs) in Crohn's disease: Decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility
Conclusions: Plasma α‐Defs 1‐3 concentrations correlate with the degree of inflammation and appear to be specific biomarkers of ileal‐CD at diagnosis. Ileal α‐Def 5 expression is permanently downregulated by methylation. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 28, 2017 Category: Allergy & Immunology Authors: Elena Cerrillo, In és Moret, Marisa Iborra, David Ramos, Enrique Busó, Luis Tortosa, Esteban Sáez‐González, Pilar Nos, Belén Beltrán Tags: Original Article Source Type: research

Alpha ‐defensins (α‐Defs) in Crohn's disease: decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 120-128, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 28, 2017 Category: Allergy & Immunology Source Type: research

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Clinical&Experimental Immunology,Volume 192, Issue 1, Page 120-128, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 28, 2017 Category: Allergy & Immunology Source Type: research

Activation of plasmacytoid dendritic cells by apoptotic particles  – mechanism for the loss of immunological tolerance in Sjögren's syndrome
Summary Sjögren's syndrome (SS) is a common autoimmune disease targeting salivary and lacrimal glands. It is strongly female‐dominant, characterized by low oestrogen levels combined with a local intracrine dihydrotestosterone defect. We hypothesized that these hormonal deficits lead to increased apoptosis of the epithelial cells and plasmacytoid dendritic cell (pDC)‐mediated proinflammatory host responses. Expression of Toll‐like receptors (TLRs)‐7 and ‐9 and cytokine profiles was studied in pDCs treated with apoptotic particles collected in consecutive centrifugation steps of media from apoptotic cells. Express...
Source: Clinical and Experimental Immunology - November 28, 2017 Category: Allergy & Immunology Authors: M. Ainola, P. Porola, Y. Takakubo, B. Przybyla, V. P. Kouri, T. A. Tolvanen, A. H änninen, D. C. Nordström Tags: Original Article Source Type: research

Lymphocyte ‐independent pathways underlie the pathogenesis of murine cytomegalovirus‐associated secondary hemophagocytic lymphohistiocytosis
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 27, 2017 Category: Allergy & Immunology Authors: Brisse Ellen, Imbrechts Maya, Mitera Tania, Vandenhaute Jessica, Berghmans Nele, Boon Louis, Wouters H. Carine, Snoeck Robert, Andrei Graciela, Matthys Patrick Tags: Original Article Source Type: research

Lymphocyte ‐independent pathways underlie the pathogenesis of murine cytomegalovirus‐associated secondary haemophagocytic lymphohistiocytosis
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 104-119, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 27, 2017 Category: Allergy & Immunology Source Type: research

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Clinical&Experimental Immunology,Volume 192, Issue 1, Page 104-119, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 27, 2017 Category: Allergy & Immunology Source Type: research

RNA ‐sequencing study of peripheral blood mononuclear cells in sporadic Meniere's disease patients: possible contribution of immunologic dysfunction to the development of this disorder
In conclusion, our study first offers a new perspective in MD development on the basis of RNA expression patterns, suggesting that immune factors might be involved in the MD pathogenesis. Remarkably, GSTM1 might be a possible candidate gene for the diagnostic biomarker of MD and provides the basis for further biological and functional investigations. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Authors: Ying Sun, Daogong Zhang, Gaoying Sun, Yafeng Lv, Yawei Li, Xiaofei Li, Yongdong Song, Jianfeng Li, Zhaomin Fan, Haibo Wang Tags: Original Article Source Type: research

RNA ‐sequencing study of peripheral blood mononuclear cells in sporadic Ménière's disease patients: possible contribution of immunologic dysfunction to the development of this disorder
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 33-45, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Source Type: research

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Clinical&Experimental Immunology,Volume 192, Issue 1, Page 33-45, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Source Type: research

Corrigendum
(Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Tags: Corrigendum Source Type: research

Erratum
(Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Tags: Corrigendum Source Type: research

Analysis of the regulatory function of natural killer cells from patients with systemic lupus erythematosus
Summary Natural killer (NK) cells participate in the regulation of the immune response. However, the immunomodulatory function of NK cells in systemic lupus erythematosus (SLE) is not well understood. The aim of this study was to evaluate the regulatory function of NK cells in SLE patients and to identify the NK cells involved in the pathogenesis of this complex disease. We analysed the expression of NK receptors and co‐stimulatory molecules in peripheral NK cells (CD3–CD56+) from SLE patients, as well as the numbers of human leucocyte antigen D‐related (HLA‐DR)/CD11c+ NK cells. In addition, NK cell regulatory func...
Source: Clinical and Experimental Immunology - November 22, 2017 Category: Allergy & Immunology Authors: D. de J. Cruz ‐González, D. Gómez‐Martin, E. Layseca‐Espinosa, L. Baranda, C. Abud‐Mendoza, J. Alcocer‐Varela, R. González‐Amaro, A. E. Monsiváis‐Urenda Tags: Original Article Source Type: research

Soluble TAM receptor tyrosine kinases in rheumatoid arthritis: Correlation with disease activity and bone destruction
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - November 17, 2017 Category: Allergy & Immunology Authors: Liling Xu, Fanlei Hu, Huaqun Zhu, Xu Liu, Lianjie Shi, Yun Li, Hua Zhong, Su Yin Tags: Original Article Source Type: research