Clinical and Experimental Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Immune cells regulate VEGF signalling via release of VEGF and antagonistic soluble VEGF receptor ‐1
In this study we aimed to characterize the effect of Zol and IL‐2 on VEGF signalling of blood‐derived immune cells in vitro. Upon stimulation with IL‐2, T cells and natural killer (NK) cells increase production of VEGF consecutively to the release of proinflammatory interferon (IFN)‐γ, and Zol accelerates this response specifically in γδ T cells. VEGF can, in turn, be antagonized by soluble VEGF receptor (sVEGFR)‐1, which is released depending on stimulatory conditions and the presence of monocytes. Additionally, malignant cells represented by leukaemia and lymphoma cell lines produce VEGF and some release sVE...
Source: Clinical and Experimental Immunology - January 4, 2018 Category: Allergy & Immunology Authors: T. Hoeres, M. Wilhelm, M. Smetak, E. Holzmann, G. Schulze ‐Tanzil, J. Birkmann Tags: Original Article Source Type: research

Driving chronicity in rheumatoid arthritis ‐ perpetuating role of myeloid cells
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - January 1, 2018 Category: Allergy & Immunology Authors: Stefano Alivernini, Barbara Tolusso, Gianfranco Ferraccioli, Elisa Gremese, Mariola Kurowska ‐Stolarska, Iain B. McInnes Tags: Review Source Type: research

Glucose ‐6‐phosphate dehydrogenase inhibition attenuates acute lung injury through reduction in NADPH oxidase derived reactive oxygen species
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 26, 2017 Category: Allergy & Immunology Authors: Ahmed Nadeem, Naif O. Al ‐Harbi, Sheikh F. Ahmad, Khalid E. Ibrahim, Nahid Siddiqui, Mohammed M. Al‐Harbi Tags: Original Article Source Type: research

Immunomodulatory activity of glycodelin: Implications in allograft rejection
This study explores the immunosuppressive property of glycodelin for its possible use in preventing graft rejection. Because glycodelin is found only in certain primates, the hypothesis was investigated in an allograft nude mouse model. It is demonstrated that treatment of alloactivated mononuclear cells with glycodelin thwarts graft rejection. Glycodelin decreases the number of activated CD4+ and CD8+ cells and downregulates the expression of key proteins known to be involved in graft demise such as granzyme‐B, EOMES, IL‐2 and pro‐inflammatory cytokines (TNF‐α and IL‐6), resulting in a weakened cell‐mediated ...
Source: Clinical and Experimental Immunology - December 22, 2017 Category: Allergy & Immunology Authors: Akanksha Dixit, Babita Balakrishnan, Anjali A. Karande Tags: Original Article Source Type: research

No augmentation of indoleamine 2,3 ‐dioxygenase (ido) activity through belatacept treatment in liver transplant recipients
Conclusion: These data provide evidence that belatacept is not associated with detectable IDO induction in the clinical transplant setting compared to tacrolimus‐treated patients. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 22, 2017 Category: Allergy & Immunology Authors: Sinda Bigenzahn, Birgit Juergens, Benedikt Mahr, Johann Pratschke, Alfred Koenigsrainer, Thomas Becker, Dietmar Fuchs, Gerald Brandacher, Alexander Kainz, Ferdinand Muehlbacher, Thomas Wekerle Tags: Original Article Source Type: research

Differential Serum Cytokine Profile in Patients with Systemic Lupus Erythematosus and Posterior Reversible Encephalopathy Syndrome
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 22, 2017 Category: Allergy & Immunology Authors: Javier Merayo ‐Chalico, Ana Barrera‐Vargas, Guillermo Juárez‐Vega, Jorge Alcocer‐Varela, Antonio Arauz, Diana Gómez‐Martín Tags: Original Article Source Type: research

Th17, synchronically increased with Treg and Breg, promoted by tumor cells via cell ‐contact in primary hepatic carcinoma
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 22, 2017 Category: Allergy & Immunology Authors: Weiwei Wang, Zhenmeng Wang, Yanghua Qin, Gusheng Tang, Gang Cai, Yaoyang Liu, Jun Zhang, Peng Zhang, Qian Shen, Lisong Shen, Weifeng Yu Tags: Original Article Source Type: research

Therapeutic potential of phages in autoimmune liver diseases
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 20, 2017 Category: Allergy & Immunology Authors: Andrzej G órski, Ewa Jończyk‐Matysiak, Marzanna Łusiak‐Szelachowska, Beata Weber‐Dąbrowska, Ryszard Międzybrodzki, Jan Borysowski Tags: Review Source Type: research

Therapeutic potential of phages in autoimmune liver diseases
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 1-6, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 20, 2017 Category: Allergy & Immunology Source Type: research

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Clinical&Experimental Immunology,Volume 192, Issue 1, Page 1-6, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 20, 2017 Category: Allergy & Immunology Source Type: research

New evidence of connections between increased O ‐GlcNAcylation and inflammasome in the oral mucosa of patients with oral lichen planus
In conclusion, the present study provides supportive evidence that increased O‐GlcNAcylation is associated with increased expression of NLRP3 inflammasome via the NF‐κB signaling pathway. These findings provide a new perspective on immunopathogenesis of OLP in relation to autoinflammation. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 16, 2017 Category: Allergy & Immunology Authors: Thao Thi Do, Chatchai Phoomak, Voraratt Champattanachai, Atit Silsirivanit, Ponlatham Chaiyarit Tags: Original Article Source Type: research

New evidence of connections between increased O ‐GlcNAcylation and inflammasome in the oral mucosa of patients with oral lichen planus
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 129-137, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 16, 2017 Category: Allergy & Immunology Source Type: research

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Clinical&Experimental Immunology,Volume 192, Issue 1, Page 129-137, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 16, 2017 Category: Allergy & Immunology Source Type: research

Immune cells regulate VEGF signaling via release of VEGF and antagonistic soluble VEGF receptor ‐1
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 13, 2017 Category: Allergy & Immunology Authors: Timm Hoeres, Martin Wilhelm, Manfred Smetak, Elisabeth Holzmann, Gundula Schulze ‐Tanzil, Josef Birkmann Tags: Original Article Source Type: research

Immune cells regulate VEGF signalling via release of VEGF and antagonistic soluble VEGF receptor ‐1
Clinical&Experimental Immunology,Volume 192, Issue 1, Page 54-67, April 2018. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - December 13, 2017 Category: Allergy & Immunology Source Type: research