Clinical and Experimental Immunology 
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Clinical&Experimental Immunology, Ahead of Print. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 20, 2018 Category: Allergy & Immunology Source Type: research
Activated leucocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy
In this study, serum levels of ALCAM were elevated in food allergy‐induced WT mice and children with food allergy. Moreover, immune responses and T cell activation were attenuated in OVA‐challenged ALCAM–/– mice. These results indicate that ALCAM regulates food allergy by affecting T cell activation.
The number of CD3+CD4+ T cells was enhanced throughout the immune tissues, especially in the small intestine, of OVA‐challenged WT mice when compared to the numbers of T cells in control WT mice. However, the number of CD3+CD4+ T cells was lower in OVA‐challenged ALCAM‐/‐ mice than in OVA‐challenged WT mice....
Source: Clinical and Experimental Immunology - February 20, 2018 Category: Allergy & Immunology Authors: Y. S. Kim, M. N. Kim, K. E. Lee, J. Y. Hong, M. S. Oh, S. Y. Kim, K. W. Kim, M. H. Sohn Tags: Original Article Source Type: research
Defective RNA sensing by RIG ‐I in severe influenza virus infection
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 17, 2018 Category: Allergy & Immunology Authors: Sofie Eg J ørgensen, Mette Christiansen, Laura Barrett Ryø, Hans Henrik Gad, Jakob Gjedsted, Peter Staeheli, Jacob Giehm Mikkelsen, Merete Storgaard, Rune Hartmann, Trine Hyrup Mogensen Tags: Original Article Source Type: research
Diminished CXCR5 expression in peripheral blood of patients with Sj ögren's syndrome may relate to both genotype and salivary gland homing
In conclusion, we link a genetic susceptibility allele for SS to a functional phenotype in terms of decreased CXCR5 expression. The decrease of CXCR5+ cells in circulation was also related to homing of B and T cells to the autoimmune target organ. Therapeutic drugs targeting the CXCR5/CXCL13 axis may be useful in SS. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 17, 2018 Category: Allergy & Immunology Authors: Lara A. Aqrawi, Margarita Ivanchenko, Albin Bj örk, Jorge I. Ramírez Sepúlveda, Juliana Imgenberg‐Kreuz, Marika Kvarnström, Philipp Haselmayer, Janicke Liaaen Jensen, Gunnel Nordmark, Karine Chemin, Kathrine Skarstein, Marie Wahren‐Herlenius Tags: Original Article Source Type: research
The role of the immune system in kidney disease
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 17, 2018 Category: Allergy & Immunology Authors: Josefine Tecklenborg, David Clayton, Stefan Siebert, Shana M. Coley Tags: Review Source Type: research
IL ‐27 – a double agent in the IL‐6 family
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 14, 2018 Category: Allergy & Immunology Authors: Gareth W Jones, David G Hill, Anna Cardus Figueras, Simon A Jones Tags: Review Source Type: research
Bronchiolitis obliterans syndrome is associated with increased p ‐glycoprotein expression and loss of glucocorticoid receptor from steroid‐resistant proinflammatory CD8+ T cells
Clinical&Experimental Immunology, EarlyView. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research
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Clinical&Experimental Immunology, Ahead of Print. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research
Correction of T cell deficiency in ZAP ‐70 knockout mice by simple intraperitoneal adoptive transfer of thymocytes
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 13, 2018 Category: Allergy & Immunology Authors: R éka Kugyelka, Zoltán Kohl, Katalin Olasz, Lilla Prenek, Tímea Berki, Péter Balogh, Ferenc Boldizsár Tags: Original Article Source Type: research
Separation of plasma ‐derived exosomes into CD3(+) and CD3(‐) fractions allows for association of immune cell and tumor cell markers with disease activity in HNSCC patients
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 12, 2018 Category: Allergy & Immunology Authors: Marie ‐Nicole Theodoraki, Thomas K. Hoffmann, Theresa L. Whiteside Tags: Original Article Source Type: research
A quarter of patients with type 1 diabetes have co ‐existing non‐islet autoimmunity; the findings of a UK population‐based family study
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 12, 2018 Category: Allergy & Immunology Authors: Aizhan Kozhakhmetova, Rebecca C Wyatt, Claire Caygill, Claire Williams, Anna E Long, Kyla Chandler, Rachel J Aitken, Janet M Wenzlau, Howard W Davidson, Kathleen M Gillespie, Alistair J K Williams Tags: Original Article Source Type: research
Immunoassay methods used in clinical studies for the detection of anti ‐drug antibodies to adalimumab and infliximab
Conclusion: Consistent with previous recommendations to improve interpretation of immunogenicity data for biologics, greater consistency in reporting of assay methods and clinical consequences of ADA formation may prove useful. Additional standardization in immunogenicity testing and reporting, application of modern, robust assays that satisfy current regulatory expectations, and implementation of international standards for marketed products may help improve our understanding of the impact of immunogenicity to biologics. This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 12, 2018 Category: Allergy & Immunology Authors: B. Gorovits, D. J. Baltrukonis, I. Bhattacharya, M. A. Birchler, D. Finco, D. Sikkema, M. S. Vincent, S. Lula, L. Marshall, T. P. Hickling Tags: Original Article Source Type: research
Corrigendum
(Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 7, 2018 Category: Allergy & Immunology Tags: Corrigendum Source Type: research
Issue Information
(Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - February 7, 2018 Category: Allergy & Immunology Tags: Issue Information Source Type: research
