Clinical and Experimental Hypertension This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

RGS10 inhibits proliferation and migration of pulmonary arterial smooth muscle cell in pulmonary hypertension via AKT/mTORC1 signaling
Conclusion: Our findings reveal the modulatory role of RGS10 in PASMC and PH via AKT/mTORC1 axis. Therefore, targeting RGS10 may serve as a novel potent method for the prevention against PH."PMID:37879890 | DOI:10.1080/10641963.2023.2271186 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - October 25, 2023 Category: Cardiology Authors: Sheng Hu Yijie Zhang Chenming Qiu Ying Li Source Type: research

Visceral fat and its dynamic change are associated with renal damage: Evidence from two cohorts
CONCLUSION: A higher level of immediate CVAI and longitudinal increasing and persistent-high patterns of CVAI were independently associated with increased risk of renal damage. Monitoring immediate level and long-term trend of CVAI may contribute to the prevention of renal damage.PMID:37871163 | DOI:10.1080/10641963.2023.2271187 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - October 23, 2023 Category: Cardiology Authors: Mengyue Lin Shiwan Wu Xiulian Deng Yequn Chen Xuerui Tan Source Type: research

MG53 alleviates hypoxia/reoxygenation-induced cardiomyocyte injury by succinylation and ubiquitination modification
CONCLUSION: SIRT7 inhibited/KAT3B promoted succinylation of MG53 at K130 sites, which suppressed ubiquitination of MG53 and upregulated its protein levels, thereby alleviating H/R-induced cardiomyocyte injury. The findings suggested that MG53 may be a potential therapy for myocardial infarction.PMID:37848382 | DOI:10.1080/10641963.2023.2271196 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - October 17, 2023 Category: Cardiology Authors: Yan Wang Hongying Zhou Jin Wu Shanshan Ye Source Type: research

Associations between central pulse pressure, microvascular endothelial function, and fluid overload in peritoneal dialysis patients
CONCLUSION: In peritoneal dialysis patients, we observed a significant association between central PP and microvascular endothelial function, indicating a connection between macrocirculation and microcirculation. However, conclusive evidence regarding fluid overload as a mediator between these circulatory systems is lacking. Further research is needed to investigate this relationship.PMID:37842909 | DOI:10.1080/10641963.2023.2267192 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - October 16, 2023 Category: Cardiology Authors: Seoyon Koh Seung-Jung Kim Shina Lee Source Type: research

TIP60 mediates stress-induced hypertension via promoting glutamate dmPFC- to- vCA1 release
This study, therefore, proposes that stressful condition induces increased expression of TIP60 which lead to the transcription of genes that result in conditions that favors glutamate release and receptor expressions hence triggering hypertension.PMID:37817460 | DOI:10.1080/10641963.2023.2259130 (Source: Clinical and Experimental Hypertension)
Source: Clinical and Experimental Hypertension - October 11, 2023 Category: Cardiology Authors: Ying Wang Min Xia Jincheng Lu Tianyu Wang Xuan Zhang Michael Ntim Bin Wang Source Type: research